Cycloheptathiophenes
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Medchemexpress LLC 2-butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 50 G
Monoethyl fumarate is the monoethyl ester of fumaric acid supplied as a research reagent and reported Nrf2 activator. It is used in biochemical research and as a preservative and polymerization agent for macromolecular materials. The compound is available as a solid and as a 10 mM solution in DMSO for experimental convenience.
- Activates Nrf2 signaling in research assays.
- High reported purity (99.62%).
- Molecular weight 144.13 g/mol and chemical formula C6H8O4.
- Available in multiple pack sizes and solution form.
- Useful as a preservative and polymerization agent for macromolecular materials.
- For research use only; not for clinical use.
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.6% | 650.7 g/mol | C37H38N4O7 | 10MM 1ML
Ocifisertib (CFI-400945) fumarate is a potent, selective inhibitor of polo-like kinase 4 (PLK4) used in preclinical and in vitro research. It exhibits subnanomolar binding affinity (Ki ≈ 0.26 nM) and low-nanomolar cellular potency (PLK4 IC50 ≈ 2.8 nM), and has demonstrated antiproliferative activity in multiple cancer cell models.
- Potent PLK4 inhibition with Ki ≈ 0.26 nM and PLK4 IC50 ≈ 2.8 nM.
- Suitable for biochemical kinase assays and cell-based proliferation studies.
- Provided as a 10 mM solution in 1 mL aliquots for convenient screening use.
- Fumarate salt form to support handling and solubility.
- Molecular formula C37H38N4O7; molecular weight 650.7 g/mol.
- High reported purity from third-party suppliers; verify lot certificate before use.
Apexbio Technology LLC Bedaquiline fumarate 845533-86-0 10mM (in 1mL DMSO)
Bedaquiline fumarate (CAS 845533-86-0) is a small-molecule inhibitor targeting ATP synthase of Mycobacterium tuberculosis It is designed to inhibit mycobacterial ATP synthase thereby disrupting ATP biosynthesis and bacterial energy metabolism Bedaquiline fumarate exerts its biological activity primarily through selective inhibition of ATP synthase In biochemical assays bedaquiline fumarate demonstrates potent inhibitory activity with an IC50 value of approximately 30 nM against M tuberculosis ATP synthase Based on these pharmacological properties bedaquiline fumarate holds research potential in studying tuberculosis pathogenesis mechanisms of antibiotic resistance and evaluating therapeutic strategies for mycobacterial infections
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 5mg
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
Medchemexpress LLC Ro60-0175 fumarate | 169675-09-6 | MFCD06798313 | 99.5% | 342.75 g/mol | C15H16ClFN2O4 | 1 ML
Ro60-0175 fumarate is a selective agonist of the serotonin 5-HT2C receptor used in neuroscience and pharmacology research. It is provided as a ready-to-use 10 mM solution in DMSO (1 mL) and in solid quantities; reported purity is 99.47%, with molecular formula C15H16ClFN2O4 and molecular weight 342.75 g/mol.
- Selective 5-HT2C receptor agonist for pharmacology studies.
- Available as 10 mM solution in DMSO (1 mL) and as solids (5, 10, 50 mg).
- High purity (~99.5%) suitable for research applications.
- Soluble in DMSO; in vitro solubility approximately 100 mg/mL.
- Storage guidance provided for powder and solutions to preserve stability.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 25 G
Monoethyl fumarate (2-Butenedioic acid (2E)-, 1-ethyl ester) is the monoethyl ester of fumaric acid supplied as a research reagent. It functions as an NRF2 activator and is used in biochemical and pharmacological studies to probe Keap1-Nrf2 signaling and inflammatory responses. Analytical documentation and high-purity material are provided for reproducible experiments.
- High purity suitable for research applications.
- Documented analytical data (COA, SDS, datasheet) available.
- Useful as an NRF2 activator probe in Keap1-Nrf2 pathway studies.
- Applicable to biochemical, pharmacological, and inflammation/immunology research.
- Available in multiple sizes for flexible experimental scaling.
Apexbio Technology LLC Formoterol fumarate 43229-80-7 50mg
Formoterol fumarate (CAS 43229-80-7) is a long-acting 2-adrenergic receptor agonist that selectively binds to 2-adrenergic receptors on bronchial smooth muscle inducing relaxation and bronchodilation Through this mechanism it modulates airway smooth muscle tone leading to sustained improvement in airflow This compound is widely utilized in research exploring pathways of bronchoconstriction receptor signaling and the pharmacological management of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD)