Cycloheptathiophenes
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
AdipoGen Hoechst 34580
Chemical. CAS 911004-45-023555-00-2 free base. Formula C27H29N7 . 3HCl. MW 561. Synthetic. The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy. The blue fluorescent Hoechst dye is a cell permeable nucleic acid stain that has multiple applications, including sensitive detection of DNA in the presence of RNA in agarose gels, automated DNA determination, sensitive determination of cell number and chromosome sorting. Useful vital stain for the flow cytometric recognition of DNA damage and other viability measurements by monitoring the emission spectral shifts of the dyes. Because this fluorescent stain labels DNA, it can also be used to visualize nuclei and mitochondria. Hoechst 34580 can be excited by violet laser at 405 nm, and emit blue/cyan fluorescence light around an emission maximum at ~440 nm. It is cell-permeable and an excellent tool for flow cytometry studies.
Medchemexpress LLC Fumarate hydratase-IN-2 (sodium salt) | 2070009-45-7 | 98.7% | 440.47 | C25H25N2NaO4 | 100 MG
Fumarate hydratase-IN-2 (sodium salt) is a cell-permeable, competitive inhibitor of fumarate hydratase with a reported Ki of 4.5 μM and nutrient-dependent cytotoxicity. Supplied as a sodium salt, it is intended for biochemical and cell-based studies probing fumarate hydratase activity and related metabolic pathways.
- Cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Reported nutrient-dependent cytotoxicity in cell assays.
- High purity suitable for research use (LCMS 98.7%).
- Molecular weight 440.47; formula C25H25N2NaO4.
- Available in small-scale solid quantities for assay preparation (for example, 100 mg).
Apexbio Technology LLC Ro 60-0175 fumarate 169675-09-6 10mg
Ro 60-0175 fumarate (CAS 169675-09-6) is a selective agonist of the 5-HT2C serotonin receptor known to specifically activate serotonergic signaling pathways By targeting 5-HT2C receptors it modulates neurotransmitter release and neuronal circuitry influencing processes such as appetite regulation mood stabilization and cognitive function Ro 60-0175 fumarate is widely utilized in neuropharmacological research to investigate central nervous system mechanisms and to assess the pharmacological properties and therapeutic potential of 5-HT2C receptor agonists in models of depression anxiety obesity and related neuropsychiatric conditions
Apexbio Technology LLC Ro 60-0175 fumarate 169675-09-6 50mg
Ro 60-0175 fumarate (CAS 169675-09-6) is a selective agonist of the 5-HT2C serotonin receptor known to specifically activate serotonergic signaling pathways By targeting 5-HT2C receptors it modulates neurotransmitter release and neuronal circuitry influencing processes such as appetite regulation mood stabilization and cognitive function Ro 60-0175 fumarate is widely utilized in neuropharmacological research to investigate central nervous system mechanisms and to assess the pharmacological properties and therapeutic potential of 5-HT2C receptor agonists in models of depression anxiety obesity and related neuropsychiatric conditions
Apexbio Technology LLC Ibutilide Fumarate 122647-32-9 100mg
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Medchemexpress LLC Cevipabulin fumarate | 849550-67-0 | 99.9% | 580.89 | 50 MG
Cevipabulin fumarate (TTI-237 fumarate) is an oral, microtubule-active, antitumor compound. It inhibits the binding of [3H]NSC 49842 to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell lines.
- Microtubule-active, antitumor compound
- Shows good activity (18-40 nM IC50 values) on ovarian, breast, prostate, and cervical tumor cell lines
- Produces sub-G1 nuclei at low concentrations (20-40 nM)
- Causes a strong G2-M block at concentrations above 50 nM
- Active via intravenous (i.v.) and oral (p.o.) administration against human tumor xenografts in mice, with good antitumor activity at 20 and 15 mg/kg
Apexbio Technology LLC Ketotifen Fumarate 34580-14-8 200mg
Ketotifen fumarate is a noncompetitive antagonist of histamine H1 receptors and functions additionally as a mast cell stabilizer It inhibits histamine-mediated allergic responses through preventing histamine receptor activation and limiting mast cell degranulation Its pharmacological activity involves suppression of calcium influx into mast cells thus inhibiting histamine release Ketotifen fumarate is extensively utilized in biomedical research focusing on allergy and asthma pathophysiology to assess mast-cell-mediated mechanisms and histamine signaling pathways In vitro studies report its IC50 values ranging approximately from 0 8 to 2 5 M depending on assay parameters and cell types This compound commonly serves as a pharmacological tool when investigating allergic inflammation asthma and histamine-dependent cellular events