Cycloheptathiophenes
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Medchemexpress LLC Tepilamide fumarate | 1208229-58-6 | 99.8% | 243.26 | 50 MG
Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses.
- Acts as a proagent of Monomethyl fumarate
- Used in research for moderate to severe chronic plaque psoriasis
- Enhances the effectiveness of oncolytic viruses
- Increases susceptibility of cancer cells to VSV∆51 infection
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 25 G
Monoethyl fumarate (2-Butenedioic acid (2E)-, 1-ethyl ester) is the monoethyl ester of fumaric acid supplied as a research reagent. It functions as an NRF2 activator and is used in biochemical and pharmacological studies to probe Keap1-Nrf2 signaling and inflammatory responses. Analytical documentation and high-purity material are provided for reproducible experiments.
- High purity suitable for research applications.
- Documented analytical data (COA, SDS, datasheet) available.
- Useful as an NRF2 activator probe in Keap1-Nrf2 pathway studies.
- Applicable to biochemical, pharmacological, and inflammation/immunology research.
- Available in multiple sizes for flexible experimental scaling.
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.6% | 650.7 g/mol | C37H38N4O7 | 10MM 1ML
Ocifisertib (CFI-400945) fumarate is a potent, selective inhibitor of polo-like kinase 4 (PLK4) used in preclinical and in vitro research. It exhibits subnanomolar binding affinity (Ki ≈ 0.26 nM) and low-nanomolar cellular potency (PLK4 IC50 ≈ 2.8 nM), and has demonstrated antiproliferative activity in multiple cancer cell models.
- Potent PLK4 inhibition with Ki ≈ 0.26 nM and PLK4 IC50 ≈ 2.8 nM.
- Suitable for biochemical kinase assays and cell-based proliferation studies.
- Provided as a 10 mM solution in 1 mL aliquots for convenient screening use.
- Fumarate salt form to support handling and solubility.
- Molecular formula C37H38N4O7; molecular weight 650.7 g/mol.
- High reported purity from third-party suppliers; verify lot certificate before use.
Medchemexpress LLC Fumarate hydratase-I 1g
Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2 2 M1]
Medchemexpress LLC Cevipabulin fumarate | 849550-67-0 | 99.9% | 580.89 | 50 MG
Cevipabulin fumarate (TTI-237 fumarate) is an oral, microtubule-active, antitumor compound. It inhibits the binding of [3H]NSC 49842 to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell lines.
- Microtubule-active, antitumor compound
- Shows good activity (18-40 nM IC50 values) on ovarian, breast, prostate, and cervical tumor cell lines
- Produces sub-G1 nuclei at low concentrations (20-40 nM)
- Causes a strong G2-M block at concentrations above 50 nM
- Active via intravenous (i.v.) and oral (p.o.) administration against human tumor xenografts in mice, with good antitumor activity at 20 and 15 mg/kg
Apexbio Technology LLC Ibutilide Fumarate 122647-32-9 10mM (in 1mL DMSO)
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Selleck Chemical LLC Zilurgisertib fumarate-5MG
Zilurgisertib fumarate(INCB-000928 fumarate NBU-928 fumarate) is a selective ALK 2 inhibitor It is under development for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva
Selleck Chemical LLC Zilurgisertib fumarate-25MG
Zilurgisertib fumarate(INCB-000928 fumarate NBU-928 fumarate) is a selective ALK 2 inhibitor It is under development for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva