Cycloheptathiophenes
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Apexbio Technology LLC Dimethyl Fumarate 624-49-7 10mM (in 1mL DMSO)
Dimethyl fumarate (CAS 624-49-7) is a small-molecule activator targeting the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway It is designed to promote Nrf2 nuclear translocation and induce transcription of antioxidant response genes thereby modulating oxidative stress response pathways Dimethyl fumarate exerts its biological activity primarily through activation of Nrf2-mediated antioxidant gene expression In cell-based assays dimethyl fumarate demonstrates Nrf2 activation activity with an IC50 value of approximately 5 M Based on these pharmacological properties dimethyl fumarate holds research potential in the study of oxidative stress inflammation and related pathophysiological processes
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.3% | 650.72 g/mol | C37H38N4O7 | 10MG
Ocifisertib fumarate is the fumarate salt of CFI-400945, an orally bioavailable small-molecule inhibitor of Polo-like kinase 4 (PLK4) for preclinical research. It is supplied as a powder for in vitro and in vivo studies and shows low-nanomolar potency against PLK4 and activity against several related kinases.
Medchemexpress LLC Monomethyl fumarate | 2756-87-8 | MFCD00063174 | 100.0% | 130.10 g/mol | C5H6O4 | 1 ML
Monomethyl fumarate is the methyl ester of fumaric acid and the active metabolite of dimethyl fumarate; it acts as a GPR109A agonist and is used in biochemical and pharmacological research. The product is offered with high purity and is available as a ready-to-use solution or as solid material for analytical and preparative applications.
- High purity suitable for research applications.
- Provided as a ready-to-use 10 mM solution in DMSO (1 mL).
- Also available in solid form for bulk use or formulation.
- Well-characterized molecular data: chemical formula C5H6O4 and molecular weight 130.10 g/mol.
- Appropriate for use as a reference compound and in studies of GPR109A-mediated pathways.
Selleck Chemical LLC Ibutilide Fumarate S2118-10mg
Ibutilide Fumarate (U-70226E Corvert Fumarate) is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current which prolongs action potential and refractory period of myocardial cells
Medchemexpress LLC 4-Piperidinemethanamine, 1-(3-chloro-4-fluorobenzoyl)-4-fluoro-N-[[5-methyl-6-(methylamino)-2-pyridinyl... | 208109-39-1 | 99.1% | 25 MG
F13714 fumarate is a selective 5-HT1A receptor biased agonist. It exhibits antidepressant-like properties after a single administration in the mouse model of chronic mild stress, primarily by targeting 5-HT1A autoreceptors. This product is intended for research use only and is not sold to patients.
- Normalizes depressive-like behavior in UCMS mice in the forced swim test (FST).
- Rescues cortical and hippocampal deficits in p-ERK1/2 levels.
- Decreases immobility in mice by 30.3% at 2 mg/kg and 19.5% at 4 mg/kg.
- Significantly and dose-dependently decreases rectal body temperature in mice.
- Exhibits antidepressant- and anxiolytic-like properties in naive rats.
Medchemexpress LLC Formoterol fumarate | 43229-80-7 | 99.95% | C19H24N2O4 . 1/2C4H4O4 | 25 MG
Formoterol fumarate is a selective β2-adrenoceptor agonist that potently and completely relaxes acetylcholine-pre-contracted human isolated segmental bronchi with a pEC50 of 8.76. It is at least as β2-adrenoceptor selective as Salbutamol and Terbutaline, making it suitable for research into chronic obstructive pulmonary disease and bronchial asthma.
- Selective β2-adrenoceptor agonist
- Abolishes contraction induced by acetylcholine in bronchioles
- Supports research into chronic obstructive pulmonary disease and bronchial asthma
- Demonstrates potent relaxation of acetylcholine-pre-contracted human isolated segmental bronchi
Medchemexpress LLC Ensitrelvir fumarate | 2757470-18-9 | 99.99% | C26H21ClF3N9O6 | 25 MG
Ensitrelvir fumarate is an orally active, non-covalent, and non-peptidic SARS-CoV-2 3CL protease inhibitor. It demonstrates significant inhibitory activity against various SARS-CoV-2 variants and has shown to inhibit intrapulmonary replication of SARS-CoV-2 in mice.
- First orally active non-covalent, non-peptidic SARS-CoV-2 3CL protease inhibitor
- Shows EC50 values of approximately 0.4 μM for wild-type and Alpha, Beta, Gamma, and Delta SARS-CoV-2 variants
- Inhibits intrapulmonary replication of SARS-CoV-2 in mice
- For research use only
Apexbio Technology LLC Ketotifen Fumarate 34580-14-8 200mg
Ketotifen fumarate is a noncompetitive antagonist of histamine H1 receptors and functions additionally as a mast cell stabilizer It inhibits histamine-mediated allergic responses through preventing histamine receptor activation and limiting mast cell degranulation Its pharmacological activity involves suppression of calcium influx into mast cells thus inhibiting histamine release Ketotifen fumarate is extensively utilized in biomedical research focusing on allergy and asthma pathophysiology to assess mast-cell-mediated mechanisms and histamine signaling pathways In vitro studies report its IC50 values ranging approximately from 0 8 to 2 5 M depending on assay parameters and cell types This compound commonly serves as a pharmacological tool when investigating allergic inflammation asthma and histamine-dependent cellular events
TARGETMOL CHEMICALS INC Dofequidar fumarate 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through the inhibition of ABCB1/P-glycoprotein (P-gp) and ABCC1/MDR-associated protein 1. Purity 99.43%