Cycloheptathiophenes
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Medchemexpress LLC 2-butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 50 G
Monoethyl fumarate is the monoethyl ester of fumaric acid supplied as a research reagent and reported Nrf2 activator. It is used in biochemical research and as a preservative and polymerization agent for macromolecular materials. The compound is available as a solid and as a 10 mM solution in DMSO for experimental convenience.
- Activates Nrf2 signaling in research assays.
- High reported purity (99.62%).
- Molecular weight 144.13 g/mol and chemical formula C6H8O4.
- Available in multiple pack sizes and solution form.
- Useful as a preservative and polymerization agent for macromolecular materials.
- For research use only; not for clinical use.
Medchemexpress LLC Zamifenacin fumarate | 127308-98-9 | 99.0% | 531.60 g/mol | C31H33NO7 | 1 ML
Zamifenacin fumarate is a gut-selective muscarinic M3 receptor antagonist provided for research use. It reduces colonic motility and is commonly used in pharmacology studies of muscarinic receptor function. The compound is available as a solid or as pre-made DMSO solution (typical 10 mM, 1 mL), with reported purity around 99.0% and molecular weight 531.60 g/mol.
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.6% | 650.7 g/mol | C37H38N4O7 | 10MM 1ML
Ocifisertib (CFI-400945) fumarate is a potent, selective inhibitor of polo-like kinase 4 (PLK4) used in preclinical and in vitro research. It exhibits subnanomolar binding affinity (Ki ≈ 0.26 nM) and low-nanomolar cellular potency (PLK4 IC50 ≈ 2.8 nM), and has demonstrated antiproliferative activity in multiple cancer cell models.
- Potent PLK4 inhibition with Ki ≈ 0.26 nM and PLK4 IC50 ≈ 2.8 nM.
- Suitable for biochemical kinase assays and cell-based proliferation studies.
- Provided as a 10 mM solution in 1 mL aliquots for convenient screening use.
- Fumarate salt form to support handling and solubility.
- Molecular formula C37H38N4O7; molecular weight 650.7 g/mol.
- High reported purity from third-party suppliers; verify lot certificate before use.
Apexbio Technology LLC Dimethyl Fumarate 624-49-7 5g
Dimethyl fumarate (CAS 624-49-7) is a small-molecule activator targeting the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway It is designed to promote Nrf2 nuclear translocation and induce transcription of antioxidant response genes thereby modulating oxidative stress response pathways Dimethyl fumarate exerts its biological activity primarily through activation of Nrf2-mediated antioxidant gene expression In cell-based assays dimethyl fumarate demonstrates Nrf2 activation activity with an IC50 value of approximately 5 M Based on these pharmacological properties dimethyl fumarate holds research potential in the study of oxidative stress inflammation and related pathophysiological processes
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.3% | 650.72 g/mol | C37H38N4O7 | 100MG
Ocifisertib (fumarate) is the fumarate salt form of a potent and selective ATP-competitive inhibitor of polo-like kinase 4 (PLK4) supplied for laboratory research. It is provided as a solid research reagent with molecular formula C37H38N4O7 and molecular weight 650.72 g/mol.
Medchemexpress LLC Monomethyl fumarate | 2756-87-8 | MFCD00063174 | 100.0% | 130.10 g/mol | C5H6O4 | 1 ML
Monomethyl fumarate is the methyl ester of fumaric acid and the active metabolite of dimethyl fumarate; it acts as a GPR109A agonist and is used in biochemical and pharmacological research. The product is offered with high purity and is available as a ready-to-use solution or as solid material for analytical and preparative applications.
- High purity suitable for research applications.
- Provided as a ready-to-use 10 mM solution in DMSO (1 mL).
- Also available in solid form for bulk use or formulation.
- Well-characterized molecular data: chemical formula C5H6O4 and molecular weight 130.10 g/mol.
- Appropriate for use as a reference compound and in studies of GPR109A-mediated pathways.