Cycloheptathiophenes
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Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
| PubChem CID | 27400 |
|---|---|
| CAS | 15574-96-6 |
| Molecular Weight (g/mol) | 295.444 |
| ChEBI | CHEBI:50212 |
| MDL Number | MFCD00864192 |
| SMILES | CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1 |
| Synonym | 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran |
| IUPAC Name | 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine |
| InChI Key | FIADGNVRKBPQEU-UHFFFAOYSA-N |
| Molecular Formula | C19H21NS |
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
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CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
| CAS | 34580-14-8 |
|---|---|
| Molecular Weight (g/mol) | 425.50 |
| SMILES | OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12 |
| IUPAC Name | (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one |
| InChI Key | YNQQEYBLVYAWNX-WLHGVMLRSA-N |
| Molecular Formula | C23H23NO5S |
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
| PubChem CID | 292644 |
|---|---|
| CAS | 40106-13-6 |
| Molecular Weight (g/mol) | 239.333 |
| MDL Number | MFCD00216932 |
| SMILES | CCOC(=O)C1=C(SC2=C1CCCCC2)N |
| Synonym | ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene |
| IUPAC Name | ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate |
| InChI Key | XTUHIGALMIGZST-UHFFFAOYSA-N |
| Molecular Formula | C12H17NO2S |
Apexbio Technology LLC Ro 60-0175 fumarate 169675-09-6 50mg
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Ro 60-0175 fumarate (CAS 169675-09-6) is a selective agonist of the 5-HT2C serotonin receptor known to specifically activate serotonergic signaling pathways By targeting 5-HT2C receptors it modulates neurotransmitter release and neuronal circuitry influencing processes such as appetite regulation mood stabilization and cognitive function Ro 60-0175 fumarate is widely utilized in neuropharmacological research to investigate central nervous system mechanisms and to assess the pharmacological properties and therapeutic potential of 5-HT2C receptor agonists in models of depression anxiety obesity and related neuropsychiatric conditions
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Apexbio Technology LLC Ro 60-0175 fumarate 169675-09-6 10mg
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Ro 60-0175 fumarate (CAS 169675-09-6) is a selective agonist of the 5-HT2C serotonin receptor known to specifically activate serotonergic signaling pathways By targeting 5-HT2C receptors it modulates neurotransmitter release and neuronal circuitry influencing processes such as appetite regulation mood stabilization and cognitive function Ro 60-0175 fumarate is widely utilized in neuropharmacological research to investigate central nervous system mechanisms and to assess the pharmacological properties and therapeutic potential of 5-HT2C receptor agonists in models of depression anxiety obesity and related neuropsychiatric conditions
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Medchemexpress LLC Tepilamide fumarate | 1208229-58-6 | 99.8% | 243.26 | 25 MG
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Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can also enhance the effectiveness of oncolytic viruses.
- Acts as a proagent of Monomethyl fumarate.
- Used in research for moderate to severe chronic plaque psoriasis.
- Can enhance the effectiveness of oncolytic viruses.
- Selectively promotes oncolytic virus infection in cancer cells without affecting healthy tissues.
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Medchemexpress LLC Diethyl fumarate | 623-91-6 | 99.0% | 172.18 | 10 G
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Diethyl fumarate is a decomposition product of Malathion 9 and a reactant in the Diels-Alder reaction. It is a reputed skin irritant and can cause non-immunologic contact urticaria on the skin. Diethyl fumarate and Curcumin hybridize to exert neuroprotective effects.
- Decomposition product of Malathion 9.
- Reactant in Diels-Alder reaction.
- Causes dose-dependent swelling of ears in guinea pigs.
- Curcumin hybrids show neuroprotective effects in C. elegans model of PD.
- For research use only.
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Medchemexpress LLC Tepilamide fumarate | 1208229-58-6 | 99.8% | 243.26 | 100 MG
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Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses.
- Oral fumaric acid ester
- Proagent of Monomethyl fumarate
- Enhances effectiveness of oncolytic viruses
- Selectively promotes oncolytic virus infection in cancer cells without affecting healthy tissues
- Used in research for moderate to severe chronic plaque psoriasis
- Potential to enhance virus-based therapy
- Solid, white to off-white appearance
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Dofequidar Fumarate | 153653-30-6 | 98.0% | 597.66 | 1 ML
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Dofequidar fumarate (MS-209) is an orally active quinoline compound that blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). It has a highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp and ABCC1/MRP-1, blocking the efflux of chemotherapeutic agents, increasing drug concentration in cancer cells, and enhancing the chemotherapeutic effect. It is for research use only and not sold to patients.
- Orally active quinoline compound
- Blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1)
- Highly potent reversing effect on multidrug-resistant tumor cells
- Competitively inhibits ABCB1/P-gp, ABCC1/MRP-1
- Blocks efflux of chemotherapeutic agents
- Increases drug concentration in cancer cells
- Enhances chemotherapeutic effect
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Tepilamide fumarate | 1208229-58-6 | 99.8% | 243.26 | 50 MG
Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses.
- Acts as a proagent of Monomethyl fumarate
- Used in research for moderate to severe chronic plaque psoriasis
- Enhances the effectiveness of oncolytic viruses
- Increases susceptibility of cancer cells to VSV∆51 infection
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Dofequidar (fumarate) | 153653-30-6 | 98.0% | 597.66 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Dofequidar fumarate (MS-209) is an orally active quinoline compound that blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). It has a highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp and ABCC1/MRP-1, blocking the efflux of chemotherapeutic agents, increasing drug concentration in cancer cells, and enhancing the chemotherapeutic effect.
- Orally active
- Blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1)
- Highly potent reversing effect on multidrug-resistant tumor cells
- Competitively inhibits ABCB1/P-gp and ABCC1/MRP-1
- Blocks the efflux of chemotherapeutic agents
- Increases drug concentration in cancer cells
- Enhances chemotherapeutic effect
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Dofequidar (fumarate) | 153653-30-6 | 98.0% | 597.66 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Dofequidar fumarate (MS-209) is an orally active quinoline compound that blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). It has a highly potent reversing effect on multidrug-resistant tumor cells. It competitively inhibits ABCB1/P-gp and ABCC1/MRP-1, blocking the efflux of chemotherapeutic agents, thereby increasing drug concentration in cancer cells and enhancing the chemotherapeutic effect. It is for research use only and not sold to patients.
- Orally active quinoline compound
- Blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1)
- Highly potent reversing effect on multidrug-resistant tumor cells
- Competitively inhibits ABCB1/P-gp and ABCC1/MRP-1
- Blocks efflux of chemotherapeutic agents
- Increases drug concentration in cancer cells
- Enhances chemotherapeutic effect
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Diethyl fumarate | 623-91-6 | 98.97% | 172.18 | 100 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Diethyl fumarate is a decomposition product of Malathion 9 (a pesticide) and a reactant in the Diels-Alder reaction. It is a reputed skin irritant and can cause non-immunologic contact urticaria on the skin. When hybridized with Curcumin, Diethyl fumarate can exert neuroprotective effects.
- Reactant in the Diels-Alder reaction.
- Exerts neuroprotective effects in combination with curcumin.
- Available in various quantities (mg, g) and solutions.
- High purity (98.97%).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Dofequidar fumarate | 153653-30-6 | 98.0% | 597.66 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Dofequidar fumarate (MS-209) is an orally active quinoline compound that blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). It has a highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp and ABCC1/MRP-1, blocking the efflux of chemotherapeutic agents, increasing drug concentration in cancer cells, and enhancing the chemotherapeutic effect. It is for research use only and not sold to patients.
- Orally active quinoline compound.
- Blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1).
- Highly potent reversing effect on multidrug-resistant tumor cells.
- Competitively inhibits ABCB1/P-gp and ABCC1/MRP-1.
- Blocks the efflux of chemotherapeutic agents.
- Increases drug concentration in cancer cells.
- Enhances the chemotherapeutic effect.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Diethyl fumarate | 623-91-6 | MFCD00064455 | 99.0% | 172.18 | 5 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Diethyl fumarate is a decomposition product of Malathion 9 (a pesticide) and acts as a reactant in the Diels-Alder reaction. It is known as a skin irritant, capable of causing non-immunologic contact urticaria. Additionally, Diethyl fumarate and Curcumin hybrids have demonstrated neuroprotective effects.
- Decomposition product of Malathion 9.
- Reactant in the Diels-Alder reaction.
- Known to cause non-immunologic contact urticaria on skin.
- When hybridized with Curcumin, it exerts neuroprotective effects.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More