Furans
Medchemexpress LLC Oxypeucedanin | 737-52-0 | 286.28 | 5 MG
Oxypeucedanin is a furanocoumarin derivative found in Angelica dahurica. It acts as an orally active inhibitor of PI3K/AKT/NF-κB, MAPK, and ROS, inducing cell cycle arrest and apoptosis. The compound also inhibits hKv1.5 channel currents and exhibits anticancer, anti-inflammatory, antioxidant, and antiarrhythmic activities.
- Acts as an orally active inhibitor of PI3K/AKT/NF-κB, MAPK, and ROS.
- Induces cell cycle arrest and apoptosis.
- Inhibits hKv1.5 channel currents with an IC50 of 76 nM.
- Demonstrates anticancer, anti-inflammatory, antioxidant, and antiarrhythmic activities.
- Inhibits viability of human prostate cancer DU145 cells.
- Inhibits expression of inflammatory factors and ROS production in RAW264.7 cells.
- Inhibits lung inflammatory damage in an LPS-induced acute lung injury mouse model.
- Alleviates severity of collagen-induced arthritis in rats.
Research Products International Corp Nitrofurantoin, 1 Gram
Nitrofurantoin works by inhibiting bacterial enzymes involved in the metabolism of certain compounds, leading to the disruption of bacterial DNA, RNA, and protein synthesis.
Researchers may use nitrofurantoin as a selective agent by incorporating it into culture media to promote the growth of cells or organisms that have been genetically engineered to express resistance to this antibiotic. It may have applications in microbiology and cell culture experiments, particularly in the context of antibiotic selection.
WARNING! This product can expose you to Nitrofurantoin, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
Apexbio Technology LLC Nitrofurazone 59-87-0 5g
Nitrofurazone (59-87-0) is a small-molecule antibacterial agent of the nitrofuran class It targets both Gram-positive and Gram-negative bacteria by generating DNA damage thereby impairing bacterial cellular replication and viability Nitrofurazone exerts its biological activity primarily through enzymatic reduction catalyzed by bacterial nitroreductases producing reactive intermediates that induce DNA strand breaks and oxidative lesions In microbiology research Nitrofurazone demonstrates inhibitory activity with reported IC50 values typically ranging from 5 30 M depending on bacterial strain and experimental conditions Based on these pharmacological properties Nitrofurazone holds research potential in bacterial susceptibility assays investigation of antibacterial mechanisms of action and studies on microbial DNA damage responses
Medchemexpress LLC BV02 | 292870-53-2 | MFCD00356631 | 99.8% | 377.36 g/mol | C20H15N3O5 | 5 MG
BV02 is a small-molecule 14-3-3 protein-protein interaction inhibitor provided as a white to off-white solid for research use. It has been reported to induce apoptosis and autophagy and to display antibacterial activity in preclinical studies. The product is supplied with stability guidelines for powder and solution storage.
eMolecules 33094-66-5 | Ambeed | 2-Nitrobenzofuran | 250mg | 588342174 | A249010 | MFCD00459786 | 163.132 | C8H5NO3
12-Azido-dodecanoic acid | Acrotein ChemBio Inc. | 80667-36-3 | MFCD00911365 | 241.335 | C12H23N3O2 | 97.000 | OC(=O)CCCCCCCCCCCN=[N+]=[N-] | 1g | 487536118
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Selleck Chemical LLC Dantrolene sodium
Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2 ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors
Chem-Impex International, Inc. 2,5-Furandicarboxylic acid | MFCD00016582 | 1G
2,5-Furandicarboxylic acid, MFCD00016582, 1G
Chem-Impex International, Inc. 2,5-Furandicarboxylic acid | MFCD00016582 | 5G
2,5-Furandicarboxylic acid, MFCD00016582, 5G
AdipoGen 2 7-Dichlorofluorescin DA
Chemical. CAS 4091-99-0. Formula C24H16Cl2O7. MW 487.29. Dichlorofluorescin diacetate H2DCFDA is a chemically reduced analog of fluorescein, used as an indicator for reactive oxygen species ROS in cells. The cell permeable non-fluorescent H2DCFDA is cleaved by cellular esterases and oxidation, and converted to the highly fluorescent 2,7-dichlorofluorescein. H2DCFDA might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Peroxynitrite is an efficient mediator of this oxidation and neither NO, superoxide, nor hydrogen peroxide alone appear to oxidize DCFH. This probe is widely used to monitoring cellular redox processes. Used as a component/substrate of the 2,7-dichlorofluorescein diacetate DCFH-DA assay to quantitate reactive oxygen species ROS. Can detect reactive oxygen species in live cells. Spectral data lambdaEx=504nm/lambdaEm=529nm.
Alkali Scientific Nitrofurantoin, 1 G
Nitrofurantoin, 1g, is a laboratory-grade antibiotic used in the treatment and study of urinary tract infections (UTIs) caused by susceptible bacteria. As a broad-spectrum antimicrobial agent, it is effective against both Gram-positive and Gram-negative bacteria. Nitrofurantoin works by disrupting bacterial protein synthesis, DNA synthesis, and metabolism, which leads to bacterial death. This 1g quantity is ideal for use in laboratory tests, including susceptibility testing and other microbial assays. Nitrofurantoin is frequently used in clinical microbiology to assess bacterial resistance patterns and study antimicrobial resistance mechanisms.
Medchemexpress LLC HY-12542A 100mg Medchemexpress, Dantrolene (sodium hemiheptahydrate) CAS:24868-20-0 Purity:>98%
Medchemexpress, HY-12542A 100mg Dantrolene (sodium hemiheptahydrate) CAS:24868-20-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Eprazinone dihydrochloride | 10402-53-6 | 99.1% | 100 MG
Eprazinone dihydrochloride is an agent possessing mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties. It acts as a neurokinin 1 receptor (NK1R) ligand. This compound shows potential for treating chronic bronchitis by improving pulmonary function and arterial partial pressure of oxygen.
- Functions as a neurokinin 1 receptor (NK1R) ligand.
- Exhibits mucolytic properties.
- Possesses secretolytic characteristics.
- Acts as an antitussive agent.
- Displays bronchial antispasmodic effects.
- Potential to improve pulmonary function.
- Potential to improve arterial partial pressure of oxygen.
![7-Ethoxybenzo[b]furan-2-carboxylic acid, 97%, Thermo Scientific™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-206559-61-7.jpg-250.jpg)
7-Ethoxybenzo[b]furan-2-carboxylic acid, 97%, Thermo Scientific™
CAS: 206559-61-7 Molecular Formula: C11H10O4 Molecular Weight (g/mol): 206.197 MDL Number: MFCD00060710 InChI Key: DQJVZIUEXPTEKX-UHFFFAOYSA-N PubChem CID: 736202 IUPAC Name: 7-ethoxy-1-benzofuran-2-carboxylic acid SMILES: CCOC1=CC=CC2=C1OC(=C2)C(=O)O