Furans
Selleck Chemical LLC Dantrolene sodium
Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2 ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors
Selleck Chemical LLC Dantrolene sodium
Dantrolene sodium(F 440) acts as a postsynaptic muscle relaxant by inhibiting Ca2 ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors
Apexbio Technology LLC Dantrolene (sodium hemiheptahydrate) 24868-20-0 200mg
Dantrolene sodium hemiheptahydrate (CAS 24868-20-0) is an orally active noncompetitive inhibitor of glutathione reductase demonstrating inhibitory activity with a Ki of approximately 111 6 M and an IC50 of around 52 3 M In addition dantrolene inhibits ryanodine receptor calcium channels RyR1 and RyR3 thereby reducing intracellular calcium release This compound is utilized in studies investigating the dysregulation of calcium homeostasis such as those related to stroke ischemia-reperfusion injury and neurodegenerative disorders It is also explored in the contexts of muscle spasticity malignant hyperthermia analgesia anti-inflammatory responses and detoxification
Medchemexpress LLC Dantrolene sodium | 14663-23-1 | 99.8% | 336.23 | 500 MG
Dantrolene sodium is an orally active, non-competitive glutathione reductase and calcium channel protein inhibitor. It inhibits Ca2+ release from RyR1 and RyR3, benefiting pathologies involving calcium homeostasis disruption, such as stroke and neurodegenerative diseases. It also relieves muscle spasms and malignant hyperthermia, with antitoxic, antipyretic, and anti-inflammatory properties.
- Orally active glutathione reductase and calcium channel protein inhibitor
- Inhibits Ca2+ release from RyR1 and RyR3
- Beneficial for calcium homeostasis disruptions
- Relieves muscle spasms and malignant hyperthermia
- Possesses antitoxic, antipyretic, and anti-inflammatory properties
Medchemexpress LLC Batabulin sodium | 195533-98-3 | MFCD22380600 | 99.8% | C13H6F6NNaO3S | 10MG
Batabulin sodium is the sodium salt of batabulin, a tubulin-targeting antitumor research compound that covalently binds a subset of β-tubulin isotypes and disrupts microtubule dynamics, inducing apoptosis in cell models. It is supplied as a high-purity reagent for biochemical and cellular studies of microtubules, tubulin covalent modification, and related pharmacology.
- Covalently binds a subset of β-tubulin isotypes and disrupts microtubule dynamics.
- Used to study apoptosis, cell division, and tubulin-targeting pharmacology.
- Supplied as a high-purity research reagent (99.8%).
- Provided in multiple pack sizes and concentration formats for lab use.
- Sodium salt form suitable for biochemical and cell-based assays.
Medchemexpress LLC Dantrolene (sodium salt) | 14663-23-1 | 99.5% | 336.2 | 100 MG
Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor and a calcium channel protein inhibitor. It inhibits the release of Ca²± from RyR1 and RyR3, which is beneficial in pathologies caused by disruptions in calcium homeostasis, such as stroke and neurodegenerative diseases. It also offers relief of muscle spasms, malignant hyperthermia, and has antitoxic, antipyretic, and anti-inflammatory properties.
- Orally active glutathione reductase and calcium channel inhibitor
- Inhibits Ca²± release from RyR1 and RyR3
- Beneficial in calcium homeostasis disruptions
- Relieves muscle spasms and malignant hyperthermia
- Antitoxic, antipyretic, and anti-inflammatory effects
- Targets calcium channel, ROS, and apoptosis
- Used in cardiovascular, neurological, and metabolic disease research
Medchemexpress LLC Batabulin sodium | 195533-98-3 | MFCD22380600 | 99.8% | 393.24 g/mol | C13H6F6NNaO3S | 5 MG
Batabulin sodium is a sodium salt antitumor research compound that covalently and selectively binds specific β-tubulin isotypes, disrupting microtubule polymerization, inducing G2/M cell-cycle arrest, and triggering apoptotic cell death. Supplied as an off-white to light-yellow solid for in vitro and in vivo research applications.
- Covalently binds to a subset of β-tubulin isotypes.
- Disrupts microtubule polymerization and induces G2/M arrest.
- Induces apoptosis in cell-based assays.
- High reported purity (~99.8%).
- Soluble in DMSO; use freshly opened solvent and ultrasonic assistance if needed.
- Store powder at 4°C; in solution store at -80°C for long-term stability.
Medchemexpress LLC Dantrolene sodium hemiheptahydrate | 24868-20-0 | MFCD07357270 | 99.8% | 399.31 g·mol⁻¹ | C14H9N4NaO5 · 3.5H2O | 500MG
Dantrolene sodium hemiheptahydrate is the sodium salt hydrate form of dantrolene, a direct-acting skeletal muscle relaxant and ryanodine receptor (RyR) inhibitor used as a research reagent in studies of muscle spasm, malignant hyperthermia, and calcium-related pathophysiology. Supplied in multiple pack sizes for laboratory use.
- High purity (99.8%).
- Inhibits RyR-mediated Ca2+ release for calcium signaling studies.
- Supplied as the hemiheptahydrate crystalline form.
- Molecular weight 399.31 g·mol⁻¹.
- Available in multiple pack sizes, including 500 mg.
- Intended for laboratory research use only.
Medchemexpress LLC HY-12542A 100mg Medchemexpress, Dantrolene (sodium hemiheptahydrate) CAS:24868-20-0 Purity:>98%
Medchemexpress, HY-12542A 100mg Dantrolene (sodium hemiheptahydrate) CAS:24868-20-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Dantrolene (sodium hemiheptahydrate) | 24868-20-0 | MFCD07357270 | 99.8% | 399.31 g/mol | C14H16N4NaO8.5 | 10MM 1ML
Dantrolene sodium hemiheptahydrate is the sodium salt hydrate form of dantrolene used as a research reagent. It acts as a direct-acting skeletal muscle relaxant and inhibitor of calcium release from the sarcoplasmic reticulum, commonly used in studies of calcium homeostasis, malignant hyperthermia models, and muscle spasm pharmacology.
- Purity 99.8% for reliable experimental consistency.
- Molecular weight 399.31 g/mol and formula C14H16N4NaO8.5.
- CAS number 24868-20-0 for substance traceability.
- Solid, yellow to orange physical appearance.
- Available in multiple pack sizes to suit laboratory needs.
- Suitable for in vitro and in vivo research into calcium-related mechanisms.
Medchemexpress LLC Bliretrigine | 1233229-75-8 | 99.4% | C20H24N4O2 | 50 MG
Bliretrigine is a sodium channel blocker that has the effect of relieving pain.
- Sodium channel blocker
- Relieves pain
- White to off-white solid appearance
- Stable under recommended storage conditions
![Medchemexpress LLC N2-{[1-ethyl-6-(4-methylphenoxy)-1H-benzimidazol-2-yl]methyl}-L-alanineamide | 1233229-75-8 | 99.4% | 352.43 g/mol | C20H24N4O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221119.png-250.jpg)
Medchemexpress LLC N2-{[1-ethyl-6-(4-methylphenoxy)-1H-benzimidazol-2-yl]methyl}-L-alanineamide | 1233229-75-8 | 99.4% | 352.43 g/mol | C20H24N4O2 | 5 MG
Bliretrigine is a research-stage sodium channel blocker supplied for laboratory studies of pain and neuronal function. It is provided in high-purity solid and solution formats for preclinical experiments and is intended for research use only, not for human therapeutic use.
- Sodium channel blocker with reported analgesic activity.
- High purity suitable for research applications (99.4%).
- Available as powder and as a DMSO solution.
- Stable when stored under recommended conditions for powder and solutions.
- Intended for research use only; not for human use.
Medchemexpress LLC Azimilide dihydrochloride | 149888-94-8 | 98.2% | 530.88 | 1 ML
Azimilide dihydrochloride is a class III antiarrhythmic agent that functions by blocking potassium channels in the heart. It is a dual blocker of IKs (IC50 = 2.6 μM) and IKr (IC50 = 1 μM), and also inhibits HERG channels, L-type calcium current (ICa), and sodium current (INa). This compound is used for the study of atrial fibrillation and ventricular fibrillation.
- Class III antiarrhythmic agent
- Blocks potassium channels in the heart
- Dual blocker of IKs and IKr
- Inhibits HERG channel
- Inhibits L-type calcium current (ICa) and sodium current (INa)
- Can be used for the study of atrial fibrillation and ventricular fibrillation
- Purity: 98.17%
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