Furofurans
Medchemexpress LLC Timosaponin C | 185432-00-2 | 10 MG
Timosaponin C is isolated from Rhizoma Anemarrhenae and shows weaker NO inhibition in N9 microglial cells. It is supplied as a high-purity chemical for research applications.
- High-purity chemical for research applications
- Isolated from Rhizoma Anemarrhenae
- Shows weaker NO inhibition in N9 microglial cells
- Sealed storage at 4°C, away from moisture and light is recommended
- In solvent, store at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Ginkgolide K | 153355-70-5 | 1 MG
Ginkgolide K, isolated from Ginkgo biloba, induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. It also possesses neuroprotective activity.
- Purity of 98.59%
- Molecular weight of 406.38
- Chemical formula C20H22O9
- Appears as a solid
- White to off-white color
- Classified as terpenoids diterpenoids
- Isolated from Ginkgo biloba
- Soluble in DMSO at 50 mg/mL
Medchemexpress LLC (S)-Terazosin | 109351-33-9 | 99.7% | 100 MG
(S)-Terazosin is the active S-enantiomer of Terazosin. It functions as a potent and high-affinity α-adrenoceptor antagonist, demonstrating specific Ki values for α1a, α1b, and α1d-adrenoceptors, as well as high affinity for α2a, α2B, and α2c-adrenoceptors. Its mechanism involves antagonism of α1-adrenoceptor subtypes in isolated tissues and antagonism at rat atrial α2B and rat vas deferens α1A and α2A receptors.
- Active S-enantiomer of Terazosin
- Potent α-adrenoceptor antagonist
- High-affinity for α1a, α1b, and α1d-adrenoceptors
- High-affinity for α2a, α2B, and α2c-adrenoceptors
- Antagonism at rat atrial α2B receptor
- Antagonism at rat vas deferens α1A and α2A receptors
Medchemexpress LLC Vociprotafib | 2172652-48-9 | 99.7% | C20H27ClN6O2S | 50 MG
Vociprotafib is an orally active, selective, and potent phosphatase SHP2 inhibitor. It blocks the activation of the RAS-RAF-MEK-ERK signaling pathway, demonstrating antitumor activity. It has been shown to accelerate tumor regressions in Osimertinib-sensitive EGFR-mutant tumors in mice and delays or reduces tumor regrowth upon cessation of treatment.
- Selective and potent SHP2 inhibitor
- Blocks RAS-RAF-MEK-ERK signaling pathway activation
- Accelerates tumor regressions in Osimertinib-sensitive EGFR-mutant tumors
- Delays and/or reduces tumor regrowth
- Effective in PDX models with resistance to Osimertinib via c-MET amplification
Medchemexpress LLC HY-U00101 1mg Medchemexpress, Octazamide CAS:56391-55-0 Purity:>98%
Medchemexpress, HY-U00101 1mg Octazamide CAS:56391-55-0 Octazamide (ICI-US 457) is an analgesic drug. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC AT-9010 tetrasodium | 1621884-18-1 | 99.7% | 627.13 | 1 MG
AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). It can inhibit SARS-CoV-2 replication.
- Potent inhibitor of NiRAN
- Inhibits SARS-CoV-2 replication
eMolecules 2-(3-Hydroxycarbonyl-2-nitrophenyl)malondialdehyde | 387360-95-4 | MFCD00278424 | 1g
Oakwood Chemical | 2-(3-Hydroxycarbonyl-2-nitrophenyl)malondialdehyde | 1g | 537680967 | 023396 | | 387360-95-4 | MFCD00278424 | 237.167 | C10H7NO6
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Medchemexpress LLC Ginkgolide J | 107438-79-9 | 424.40 | 5 MG
Ginkgolide J is a primary component of the non-flavone fraction found in Ginkgo biloba. It exhibits neuroprotective and anti-neuronal apoptotic properties, making it suitable for studies on neurological protection and cellular apoptosis.
- Reduces apoptotic damage in cultured chick embryonic neurons
- Intended for research use only
Medchemexpress LLC Ginkgolide J | 107438-79-9 | MFCD03093737 | 100.0% | 424.40 g·mol⁻¹ | C20H24O10 | 10 MG
Ginkgolide J is a naturally occurring diterpenoid from Ginkgo biloba used in research for its reported neuroprotective and anti-apoptotic activity (IC50 12-54 μM). It is supplied as a high-purity powder intended for laboratory use, with solubility information and handling documentation provided for in vitro and in vivo formulation.
- Natural diterpenoid with neuroprotective activity.
- Reported IC50 range of 12-54 μM in published assays.
- High purity suitable for research applications.
- Soluble in DMSO; in vivo formulation protocols available.
- Provided in mg-scale packs for small-scale experiments.
- Documentation includes data sheet, COA, and SDS for handling and quality confirmation.
Medchemexpress LLC Isosorbide dinitrate | 87-33-2 | MFCD00868238 | 99.9% | 236.14 | C6H8N2O8 | 10 MG
Isosorbide dinitrate is a nitric oxide (NO) donor used as a research reagent and analytical standard for studies of vasodilation, myocardial infarction, and cardiac remodeling. It is supplied as a high-purity solid suitable for in vitro and analytical applications.
- High purity (99.9%).
- Chemical formula C6H8N2O8; molecular weight 236.14.
- CAS number 87-33-2.
- Soluble in DMSO (100 mg/mL); ultrasonic agitation recommended.
- Store protected from light at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Available as solid packs (5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg) and as 10 mM solutions in DMSO.
Medchemexpress LLC (S)-Terazosin | 109351-33-9 | 99.7% | 50 MG
(S)-Terazosin is the active S-enantiomer of Terazosin and a potent, high-affinity α-adrenoceptor antagonist. It exhibits strong binding to α1a, α1b, and α1d-adrenoceptors, as well as significant affinity for α2a, α2B, and α2c-adrenoceptors, making it a powerful antagonist in isolated tissues.
- Active S-enantiomer of Terazosin.
- Potent and high-affinity α-adrenoceptor antagonist.
- Antagonizes α1a, α1b, and α1d-adrenoceptors.
- Exhibits affinity for α2a, α2B, and α2c-adrenoceptors.
- Demonstrates antagonism at rat atrial α2B receptor.
- Antagonizes rat vas deferens α1A and α2A receptors.
eMolecules 211427-08-6 | Medchem Express | Diquafosol (tetrasodium) | 5mg | 446273061 | HY-B0606 | 878.233 | C18H22N4Na4O23P4
ChemScene | 3-Bromo-[11-biphenyl]-4-amine | 100mg | 711935502 | CS-0254243 | 41738-70-9 | MFCD00034057 | 248.123 | C12H10BrN
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eMolecules 91183-98-1 | Medchem Express | UDP-GlcNAc (disodium) | 5mg | 446260215 | HY-112174 | MFCD00799985 | 651.318 | C17H25N3Na2O17P2
Medchem Express | UDP-GlcNAc (disodium) | 5mg | 446260215 | HY-112174 | 91183-98-1 | MFCD00799985 | 651.318 | C17H25N3Na2O17P2
Medchemexpress LLC 3-Methyluridine | 2140-69-4 | 99.1% | 258.23 | 50 MG
3-Methyluridine is a methylated nucleotide found in ribosomal RNA. It introduces a methyl group at the N3 position of uracil, influencing the secondary structure stability and base pairing ability of RNA, and regulating ribosome function.
- Primarily targets specific base sites of RNA molecules such as 23S rRNA.
- Regulates ribosome function, including ribosomal subunit binding and tRNA interaction.
- Utilized as a key raw material for synthesizing modified nucleotides.
- Used for constructing RNA oligonucleotides with methylation modifications.
- Helps study the effects of RNA methylation on gene expression and drug resistance.