Imidazopyrimidines
Adenine Hydrochloride, Cell Culture Reagent Grade, MP Biomedicals™
CAS: 6055-72-7 Molecular Formula: C5H8ClN5O Molecular Weight (g/mol): 189.60 MDL Number: MFCD11046306 InChI Key: MYRDTAUFFBYTHA-UHFFFAOYSA-N Synonym: 7h-purin-6-amine hydrochloride hydrate,adenine hydrochloride hydrate,adenine hydrochloride hemihydrate,1h-purin-6-amine monohydrochloride hydrate 2:1,ade hydrate hydrochloride,purine-6-ylamine, chloride, hydrate,c5h5n5.hcl.h2o,adenine hydrochloride,adeninehydrochloridehemihydrate,vitamin b4 hydrate hydrochloride PubChem CID: 24211900 IUPAC Name: 7H-purin-6-amine hydrate hydrochloride SMILES: O.Cl.NC1=C2NC=NC2=NC=N1
Thermo Scientific Chemicals Adenine sulfate, 98%, synthetic
CAS: 321-30-2 Molecular Formula: C10H12N10O4S Molecular Weight (g/mol): 368.33 MDL Number: MFCD00213655 InChI Key: LQXHSCOPYJCOMD-UHFFFAOYSA-N Synonym: adenine sulfate,adenine hemisulfate,7h-purin-6-amine sulfate 2:1,adeninsulfat,adeninium sulfate,adenine sulfate 2:1,adeninsulfat german,1h-purin-6-amine, sulfate 2:1,diadenine sulphate,unii-741gjf3k9m PubChem CID: 9449 IUPAC Name: 7H-purin-6-amine;sulfuric acid SMILES: OS(O)(=O)=O.NC1=C2NC=NC2=NC=N1.NC1=C2NC=NC2=NC=N1
Sigma Aldrich Fine Chemicals Biosciences Adenine hydrochloride hydrate powder, BioReagent, suitable for cell culture | 2922-28-3 | MFCD00150864 | 5g
Adenine hydrochloride hydrate powder, BioReagent, suitable for cell culture | Purity: 99% | MW: 171.59 | 2922-28-3 | MFCD00150864 | 5g
Sigma Aldrich Fine Chemicals Biosciences Adenine hydrochloride hydrate powder, BioReagent, suitable for cell culture | 2922-28-3 (anhydrous) | MFCD00150864 | 1G
Adenine hydrochloride hydrate powder, BioReagent, suitable for cell culture | Purity: >=99% | 2922-28-3 (anhydrous) | MFCD00150864 | 1G
Sigma Aldrich Fine Chemicals Biosciences Adenine hydrochloride hydrate powder, BioReagent, suitable for cell culture | 2922-28-3 (anhydrous) | MFCD00150864 | 25G
Adenine hydrochloride hydrate powder, BioReagent, suitable for cell culture | Purity: >=99% | 2922-28-3 (anhydrous) | MFCD00150864 | 25G
Medchemexpress LLC 2-Fluoroadenine | 700-49-2 | MFCD01632749 | 153.12 | 100 MG
2-Fluoroadenine is a toxic purine base that exhibits toxicity in both nonproliferating and proliferating tumor cells. It is utilized in anticancer research.
- Exhibits toxicity in nonproliferating and proliferating tumor cells.
- Inhibits CEM cell growth by targeting enzymes involved in RNA or protein synthesis.
- Shows cytotoxicity in nonproliferating MRC-5 cells.
- Inhibits protein, RNA, and DNA syntheses in Balb-3T3 cells.
Medchemexpress LLC 6H-Purine-6-thione, 1,2,3,9-tetrahydro-, hydrate (1:1) | 6112-76-1 | 99.9% | 170.19 | 500 MG
6-Mercaptopurine hydrate is a purine analogue that acts as an antagonist of endogenous purines. It has been widely used as an antileukemic agent and immunosuppressive agent.
- Induces NR4A3 transcriptional activity.
- Increases NR4A3 protein levels.
- Increases cell surface GLUT4 in basal and insulin-stimulated cells.
- Increases phospho-AS160.
- Significantly inhibits EcSTH-induced phosphorylation of AMPK and ACC1.
- Promotes an increase in S phase cell population in fetal telencephalons.
- Promotes an increase in G2/M phase cell population in fetal telencephalons.
- Increases sub-G1 phase cell population (apoptotic cells).
- Inhibited expression of CAV1 protein in MM1S cells.
- Further promoted bortezomib-mediated survival of MM-bearing mice.
Medchemexpress LLC 6-Mercaptopurine hydrate | 6112-76-1 | 99.9% | 170.19 | 100 MG
6-Mercaptopurine hydrate is a purine analogue that acts as an antagonist of endogenous purines. It has been widely used as an antileukemic and immunosuppressive agent.
- Purine analogue.
- Antagonist of endogenous purines.
- Induces NR4A3 transcriptional activity 1.6- to 11-fold in a dose-responsive manner.
- Leads to a dose-dependent increase in NR4A3 protein levels.
- Increases cell surface GLUT4 in both basal cells (1.8- to 3.6-fold) and insulin-stimulated cells (2.9- to 4.4-fold) over controls.
- Increases phospho-AS160 significantly in a dose-responsive manner under both basal and insulin-stimulated conditions.
- Induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain.
- Purity: 99.9%.
- Appearance: Solid.
- Color: Light yellow to yellow.
- Used as an antileukemic agent.
- Used as an immunosuppressive agent.
![Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4], USP, 500 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661418.jpg-250.jpg)
Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4], USP, 500 G
Adenine [6 Aminopurine] [Vitamin B4] is a USP grade reagent available in a 500g bottle. As a purine nucleobase, adenine plays an essential role in nucleic acid metabolism and is commonly used in cell culture media for research in molecular biology and biochemistry. Adenine is a precursor for the synthesis of DNA and RNA and is important for the growth and maintenance of various cell types in vitro. It is widely used in experiments involving cellular processes, including the study of cell growth, gene expression, and enzyme activity. This high-quality reagent is ideal for laboratory applications that require the precise formulation of culture media or for the synthesis of compounds that involve adenine.
Medchemexpress LLC 1-Methylxanthine | 6136-37-4 | 166.14 | 50 MG
A caffeine derivative, this compound is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine). It has been shown to enhance the radiosensitivity of tumor cells. This product is for research use only and not for sale to patients.
- Caffeine derivative
- Human urinary metabolite of caffeine and theophylline
- Enhances the radiosensitivity of tumor cells
- Exhibits similar activities to other naturally occurring methylxanthines
Medchemexpress LLC 1-Methylxanthine | 6136-37-4 | 166.14 | 1 ML
1-Methylxanthine is a caffeine derivative that serves as an essential human urinary metabolite of caffeine and theophylline. It enhances the radiosensitivity of tumor cells and is intended for research and analytical applications.
- Caffeine derivative and human urinary metabolite
- Enhances radiosensitivity of tumor cells
- Molecular formula: C6H6N4O2
- Molecular weight: 166.14
- Purity: 98.1% (HPLC)
- Stable for years as powder, months in solvent
Medchemexpress LLC BioE-1115 | 1268863-35-9 | 98.2% | 10 MG
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. It also acts as a potent casein kinase 2α inhibitor with an IC50 of ~10 μM.
- Highly selective PASK inhibitor (IC50 ~4 nM).
- Potent casein kinase 2α inhibitor (IC50 ~10 μM).
- Induces dose-dependent loss of PASK phosphorylation in HEK293 cells.
- Reduces SREBP activity in HepG2 cells without affecting cell morphology or growth.
- Suppresses SREBP-1c target gene expression and SREBP-1 maturation in liver in vivo.
- Decreases insulin resistance, hepatic/serum triglycerides, and serum glucose dose-dependently.
- Does not cause significant changes in liver or body weight.
![Alkali Scientific BPA [n Benzyl 9 (2 tetrahydropyranyl) adenine], 100 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661504.jpg-250.jpg)
Alkali Scientific BPA [n Benzyl 9 (2 tetrahydropyranyl) adenine], 100 Mg
Benzyl Adenine (BPA) is a plant growth regulator in powder form, used extensively in laboratories to promote cell division and enhance plant growth. This cytokinin is known to stimulate shoot formation and can delay senescence in plant tissues. BPA is typically used in tissue culture and plant regeneration studies to enhance shoot proliferation and improve cloning efficiency in various plant species. By promoting cell division and modulating growth, BPA helps researchers and horticulturists achieve higher success rates in propagation and genetic improvement programs. It is widely applied in agricultural research, particularly in crop improvement and plant biotechnology.
![Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4] USP, 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661494.jpg-250.jpg)
Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4] USP, 25 G
Adenine (Vitamin B4) USP, 25g is a critical reagent used in the study of nucleic acids, genetics, and cell metabolism. This purine nucleobase is integral to the synthesis of ATP, a molecule responsible for cellular energy transfer. Adenine is also a building block of DNA and RNA, essential for cellular growth, division, and function. This 25g quantity is suitable for use in smaller-scale experiments, genetic studies, and the production of synthetic nucleotides. Adenine is also used in research involving purine metabolism, cell culture media, and as a standard reagent for studying genetic material. It is a vital tool in molecular biology and biochemistry laboratories.
![Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4] USP, 1 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661464.jpg-250.jpg)
Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4] USP, 1 Kg
Adenine (Vitamin B4) is a purine nucleobase that plays a key role in cellular energy production, DNA and RNA synthesis, and metabolic regulation. The USP grade 1kg formulation is ideal for use in biochemical and pharmaceutical research. Adenine is used as a precursor in nucleotide biosynthesis and is integral in many cellular functions, including the synthesis of ATP (adenosine triphosphate), essential for energy transfer in cells. It is also utilized in genetic research, cell culture media, and studies on purine metabolism. This high-quality reagent is essential in DNA/RNA synthesis and other biological studies, making it a valuable component in a wide range of scientific experiments.