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Filtered Search Results
Medchemexpress LLC Nevadensin | 10176-66-6 | MFCD08689947 | 344.32 | 20 MG
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Nevadensin is a natural flavonoid and a selective human carboxylesterase 1 (hCE1) inhibitor. It demonstrates greater selectivity for hCE1 over hCE2.
- Induces apoptosis and DNA damage in cancer cells.
- Possesses anti-inflammatory, anti-tumor, anti-hypertensive, anti-tubercular, antitussive, antioxidant, and anti-microbial activities.
- Inhibits hCE1 with an IC50 of 2.64 μM.
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Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g·mol⁻¹ | C21H19F4N5O3 | 10 MG
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PARP-2-IN-1 is a potent, selective inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) used in research on DNA damage response and programmed cell death. It exhibits an IC50 of 11.5 nM against PARP-2 and is supplied as a high-purity small-molecule reagent for laboratory studies.
- Potent and selective PARP-2 inhibition (IC50 11.5 nM).
- High purity suitable for research (>99.5% by HPLC).
- Well-characterized molecular properties (C21H19F4N5O3, 465.40 g·mol⁻¹).
- Available in small mg-scale quantities for laboratory research.
- Suitable for biochemical and cell-based assays studying DNA repair and apoptosis.
- Provided with product datasheet and analytical data.
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eMolecules 58706-66-4 | 3-(N-METHYLACETAMIDO)PROPANOIC ACID | AstaTech | MFCD04037898 | 145.158 | C6H11NO3 | 95.000 | CN(CCC(O)=O)C(C)=O | 0.25g | 493153554
3-(N-METHYLACETAMIDO)PROPANOIC ACID | AstaTech | 58706-66-4 | MFCD04037898 | 145.158 | C6H11NO3 | 95.000 | CN(CCC(O)=O)C(C)=O | 0.25g | 493153554
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Medchemexpress LLC SIRT-IN-2 | 1431411-66-3 | 98.1% | 383.49 | 50 MG
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SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 nM, respectively. It is described as one of the most potent truncated pan SIRT1/2/3 inhibitors. SIRT-IN-2 (compound 31) binds identically in the catalytic active site (RMS=0.29), occupying the nicotinamide C-pocket and acetyl lysine substrate channel.
- Potent inhibitor of SIRT1/2/3
- IC50s of 4, 4, 7 nM for SIRT1, SIRT2, and SIRT3
- Truncated pan SIRT1/2/3 inhibitor
- Binds in the catalytic active site
- Occupies nicotinamide C-pocket and acetyl lysine substrate channel
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Medchemexpress LLC Dx3-213b | 2749555-66-4 | 99.7% | 478.57 g/mol | C20H28F2N2O5S2 | 5 MG
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DX3-213B is a potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor used in preclinical research. It disrupts mitochondrial ATP production and exhibits cellular activity in cancer models, making it useful for mechanistic studies of mitochondrial function and cancer metabolism. Not for human use.
- Highly potent complex I inhibition (IC50 = 3.6 nM)
- Impairs ATP generation in cells (IC50 = 11 nM)
- Inhibits growth of pancreatic cancer cell line (GI50 = 11 nM)
- High chemical purity suitable for biochemical assays
- Available as solid and DMSO solution for assay flexibility
- Intended for mechanistic mitochondrial and cancer metabolism research
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eMolecules 181144-66-1 | Medchem Express | Co 102862 | 5mg | 722714018 | HY-108504 | MFCD00953614 | 273.267 | C14H12FN3O2
Medchem Express | NRX-1933 | 5mg | 713706709 | HY-144984 | 2763260-30-4 | 350.261 | C14H9F3N6O2
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eMolecules 1355573-66-8 | ChemScene | Benzyl (22-dimethoxyethyl)(methyl)carbamate | 250mg | 686213821 | CS-0369811 | 253.298 | C13H19NO4
AbaChemScene | Bicyclo[3.1.0]hexane-6-carboxylic acid | 100mg | 410752187 | CS-0046674 | 16650-37-6 | MFCD06804454 | 126.155 | C7H10O2
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eMolecules 102916-66-5 | Medchem Express | 2-Deoxyribose 5-phosphate (disodium) | 5mg | 721309687 | HY-147061 | 258.073 | C5H9Na2O7P
Medchem Express | Lupiwighteone | 5mg | 705861611 | HY-N3354 | 104691-86-3 | MFCD06796683 | 338.359 | C20H18O5
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eMolecules 1214387-66-2 | 3-METHYL-4-(TRIFLUOROMETHYL)BENZOIC ACID ETHYL ESTER | AstaTech | MFCD14698275 | 232.202 | C11H11F3O2 | 95.000 | CCOC(=O)c1ccc(c(C)c1)C(F)(F)F | 1g | 296384189
3-METHYL-4-(TRIFLUOROMETHYL)BENZOIC ACID ETHYL ESTER | AstaTech | 1214387-66-2 | MFCD14698275 | 232.202 | C11H11F3O2 | 95.000 | CCOC(=O)c1ccc(c(C)c1)C(F)(F)F | 1g | 296384189
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eMolecules 74290-66-7 | 2-Amino-3,5-dibromo-6-methylpyrazine | ChemScene | MFCD08705764 | 266.924 | C5H5Br2N3 | 98.000 | Cc1nc(N)c(Br)nc1Br | 100mg | 801476141
2-Amino-3,5-dibromo-6-methylpyrazine | ChemScene | 74290-66-7 | MFCD08705764 | 266.924 | C5H5Br2N3 | 98.000 | Cc1nc(N)c(Br)nc1Br | 100mg | 801476141
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Medchemexpress LLC PGAM1-IN-2 | 2438637-66-0 | 98.0% | 10 MG
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PGAM1-IN-2 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 2.1 μM. This compound inhibits H1299 proliferation with an IC50 of 33.8±6.1 μM.
- Potent phosphoglycerate mutase 1 inhibitor
- Inhibits H1299 proliferation
- Suitable for research applications
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Medchemexpress LLC FKBP12 PROTAC RC32 | 2375555-66-9 | 97.0% | 100 MG
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FKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader that utilizes PROTAC technology. It is a conjugate of Rapamycin and a ligand for a Cereblon E3 ubiquitin ligase, designed to efficiently degrade FKBP12 protein.
- Potent degrader of FKBP12
- Based on PROTAC technology
- Contains conjugation of Rapamycin and a ligand for a Cereblon E3 ubiquitin ligase
- Efficiently degrades FKBP12 protein in most organs (in vivo studies)
- Induces FKBP12 protein degradation in human Jurkat cells (DC50 ~0.3 nM)
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eMolecules 461000-66-8 | Medchem Express | Eact | 5mg | 533802217 | HY-103368 | MFCD03115431 | 428.5 | C22H24N2O5S
Medchem Express | Deoxynyboquinone | 1mg | 761041685 | HY-108992 | 96748-86-6 | 284.271 | C15H12N2O4
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![eMolecules 159730-12-8 | 6-Methyltryptamine hydrochloride | Chem-Impex | MFCD01074517 | 210.710 | C11H15ClN2 | 99.000 | Cl.Cc1ccc2c(CCN)c[nH]c2c1 | 1g | 112755382](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502178210.JPG-250.jpg)
eMolecules 159730-12-8 | 6-Methyltryptamine hydrochloride | Chem-Impex | MFCD01074517 | 210.710 | C11H15ClN2 | 99.000 | Cl.Cc1ccc2c(CCN)c[nH]c2c1 | 1g | 112755382
6-Methyltryptamine hydrochloride | Chem-Impex | 159730-12-8 | MFCD01074517 | 210.710 | C11H15ClN2 | 99.000 | Cl.Cc1ccc2c(CCN)c[nH]c2c1 | 1g | 112755382
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Medchemexpress LLC Parp-2-in-1 | 2115698-83-2 | 99.6% | 465.40 g/mol | C21H19F4N5O3 | 5 MG
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A potent, selective small-molecule inhibitor of poly(ADP-ribose) polymerase 2 (PARP-2) with a reported IC50 of 11.5 nM. The compound has molecular formula C21H19F4N5O3, molecular weight 465.40 g/mol, and is supplied as a white to off-white solid for use in biochemical and cellular research.
- Potent PARP-2 inhibition (IC50 11.5 nM).
- High chemical purity (99.6%).
- Molecular formula C21H19F4N5O3 and molecular weight 465.40 g/mol for easy reference.
- Supplied as a solid suitable for handling and storage.
- Manufacturer documentation available: data sheet, COA, and SDS for characterization.
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