Lactams
Medchemexpress LLC Thalidomide-NH-C10-NH2 hydrochloride | 2460022-53-9 | 464.99 | C23H33ClN4O4 | 10 MG
Thalidomide-NH-C10-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand supplied as a hydrochloride salt in solid form for research use. It is intended for incorporation into PROTACs and other E3 ligase recruiting conjugates for chemical biology and medicinal chemistry studies.
- Thalidomide-derived cereblon ligand for E3 ligase recruitment.
- Suitable for PROTAC construction and linker conjugation.
- Provided as a solid hydrochloride salt for stability and handling.
- Available in small milligram packages appropriate for synthesis and assays.
- Store sealed, away from moisture and light; follow supplier storage guidance.
Medchemexpress LLC Thalidomide-4-O-C9-NH2 hydrochloride | >98.0% | 451.94 g/mol | C22H30ClN3O5 | 10 MG
Thalidomide-4-O-C9-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand intended for use in targeted protein degradation and PROTAC development. Supplied as the hydrochloride salt for conjugation chemistry, the compound is offered for research use and is commonly provided in small milligram quantities for medicinal chemistry and chemical biology applications.
- Acts as a cereblon (CRBN) ligand for E3 ligase recruitment.
- Designed for use in PROTAC and targeted protein degradation research.
- Provided as a hydrochloride salt suitable for conjugation chemistry.
- Reported purity ≥98% according to vendor listings.
- Molecular weight ~451.94 g/mol; formula C22H30ClN3O5.
- Store sealed at -20°C to maintain stability.
Medchemexpress LLC Thalidomide-5-O-C6-NH2 hydrochloride | 2761398-05-2 | 409.86 | 5 MG
Thalidomide-5-O-C6-NH2 hydrochloride is a cereblon ligand based on Thalidomide. It is utilized in the recruitment of CRBN protein and can be linked to a ligand for protein via a linker to form PROTACs. It is a solid with a white to off-white appearance.
- Cereblon ligand
- Utilized in CRBN protein recruitment
- Can form PROTACs when linked to a protein ligand
- Available as a white to off-white solid
- Shipped at room temperature
- Stored at -20°C, protected from light and under nitrogen
Medchemexpress LLC Thalidomide-4-O-C14-NH2 hydrochloride | 99.9% | 522.08 | 5 MG
Thalidomide-4-O-C14-NH2 hydrochloride is a cereblon ligand derived from Thalidomide and is utilized for the recruitment of CRBN protein. It can be linked to a protein ligand via a linker to create PROTACs, which are relevant for research purposes.
- Thalidomide-based cereblon ligand
- Recruits CRBN protein
- Can be connected to a protein ligand by a linker to form PROTACs
- For research use only
Medchemexpress LLC Thalidomide-5-O-C7-NH2 hydrochloride | 98.13% | 423.89 | 5 MG
Thalidomide-5-O-C7-NH2 hydrochloride is a Thalidomide (HY-10984)-based cereblon ligand that is used for recruiting CRBN protein. It can be connected to a ligand for protein by a linker to form PROTACs.
- Used in the recruitment of CRBN protein
- Can be connected to a ligand for protein by a linker
- Forms PROTACs
- For research use only
Medchemexpress LLC Thalidomide-4-O-C9-NH2 (hydrochloride) | 99.3% | 451.94 | 5 MG
Thalidomide-4-O-C9-NH2 (hydrochloride) is a solid laboratory chemical with a molecular weight of 451.94 and the chemical formula C22H30ClN3O5. It is stable under recommended storage conditions.
- Solid appearance, light yellow to yellow
- Purity of 99.3%
- Stable under recommended storage conditions
- Long-term storage at -20°C (solid) or -80°C (in solvent)