Lactams
eMolecules 17557-84-5 | 3-Azetidinone Hydrochloride | Accela ChemBio (ASD) | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 588340315
3-Azetidinone Hydrochloride | Accela ChemBio (ASD) | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 588340315
Medchemexpress LLC Thalidomide-5-br | 26166-92-7 | MFCD30188073 | 98.4% | 337.13 | C13H9BrN2O4 | 5 MG
Thalidomide-5-Br is a brominated derivative of thalidomide provided for research use. It is described as a compound with a bromodomain and is used in preclinical studies of inflammation, tumor biology, and neurology.
- Used in research related to inflammation, tumor biology, and neurology.
- High purity suitable for biochemical assays and medicinal chemistry.
- Available in small milligram quantities for discovery studies.
- Stable at room temperature for extended storage under recommended conditions.
- Contains a bromodomain-containing structure for target engagement studies.
Research Products International Corp Aztreonam 25 MG
Aztreonam is a synthetic monocyclic beta-lactam antibiotic, with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum.
Medchemexpress LLC Thalidomide-O-amido-PEG2-C2-NH2 (TFA) | 1957235-75-4 | 576.48 | 25 MG
Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and 2-unit PEG linker used in PROTAC technology. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- E3 ligase ligand-linker conjugate
- Incorporates thalidomide-based cereblon ligand
- 2-unit PEG linker
- Used in PROTAC technology
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Thalidomide-O-amido-C6-NH2 TFA | 1950635-14-9 | 99.8% | 544.48 | 1 G
Thalidomide-O-amido-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, and can be used in the synthesis of PROTACs.
- Can be used in the synthesis of PROTACs.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Incorporates the Thalidomide based cereblon ligand.
Apexbio Technology LLC Aztreonam 78110-38-0 100mg
Aztreonam (CAS 78110-38-0) is a synthetic monocyclic -lactam antibiotic targeting penicillin-binding protein 3 (PBP3) It is designed to bind to PBP3 thereby disrupting bacterial cell wall synthesis and inhibiting bacterial growth Aztreonam exerts its biological activity primarily through inhibition of cell wall synthesis in aerobic Gram-negative bacteria In in vitro studies Aztreonam demonstrates selective antibacterial activity with reported IC50 values ranging from 0 05 8 g/mL against sensitive Gram-negative bacterial strains depending on species and experimental conditions Based on these pharmacological properties Aztreonam holds research potential in studies of bacterial resistance mechanisms -lactamase susceptibility profiles and evaluation of antibiotic permeability
![eMolecules [cis-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methanol | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502160039.JPG-250.jpg)
eMolecules [cis-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methanol | 1g
Pharmablock | [cis-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methanol | 1g | 551294267 | PBU4956 | 285.503 | C15H31NO2Si
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Medchemexpress LLC Thalidomide-propargyl | 2098487-39-7 | 99.97% | 312.28 | 10 MG
Thalidomide-propargyl is a Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to a ligand for protein by a linker to form IMiD containing PROTACs. It is a click chemistry reagent containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Thalidomide-based Cereblon ligand
- Used in the recruitment of CRBN protein
- Can form IMiD containing PROTACs when connected to a ligand for protein by a linker
- Click chemistry reagent
- Contains an Alkyne group
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Medchemexpress LLC Thalidomide-NH-PEG4-COOH | 2412056-48-3 | 96.7% | 521.52 | 50 MG
Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP.
- E3 ligase ligand-linker conjugate
- Used for synthesizing dCBP-1
- Potent and selective heterobifunctional degrader of p300/CBP
- Purity of 96.7%
- Appearance: yellow to green (solid-liquid mixture)
- Store at -20°C, protect from light
Cayman Chemical AzIdo-ThalIdomIde 10mg
A PROTAC building block; contains thalidomide, which is a ligand for the E3 ubiquitin ligase cereblon, and can be conjugated to alkynylated ligands for target proteins via click chemistry; has been used in the synthesis of a SirReal-based PROTAC for the degradation of Sirt2 in cells
Medchemexpress LLC Thalidomide-Piperazine 5-fluoride | 2222114-22-7 | 96.47% | 360.34 | 250 MG
Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand and a linker utilized in PROTAC technology, designed for research purposes.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates cereblon ligand
- Linker utilized in PROTAC technology
- Intended for research use only
- Purity: 96.47%
- Molecular weight: 360.34
- Solid appearance
- Color: Light yellow to green yellow
- Soluble in DMSO
Medchemexpress LLC Thalidomide-O-C6-azide | 2411389-65-4 | 99.1% | 399.40 | 100 MG
Thalidomide-O-C6-azide is a synthesized E3 ligase ligand-linker conjugate, incorporating the Thalidomide based cereblon ligand and a linker used in PROTAC technology. This click chemistry reagent contains an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules or strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. It is designed for research applications related to PROTACs, which utilize the ubiquitin-proteasome system to degrade target proteins.
- Incorporates cereblon ligand and a linker for PROTAC technology
- Click chemistry reagent with an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Designed for research in protein degradation via PROTACs
Medchemexpress LLC (S)-Thalidomide | 841-67-8 | 99.5% | 258.23 | 100 MG
(S)-Thalidomide is the S-enantiomer of Thalidomide. It possesses immunomodulatory, anti-inflammatory, antiangiogenic, and pro-apoptotic effects. (S)-Thalidomide induces teratogenic effects by binding to cereblon (CRBN).
- Immunomodulatory effects
- Anti-inflammatory effects
- Antiangiogenic effects
- Pro-apoptotic effects
- Induces teratogenic effects by binding to cereblon (CRBN)
- For research use only