Lactams
eMolecules 28562-58-5 | 4-Benzoyloxy-2-azetidinone | Combi-Blocks | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 1g | 267200512
4-Benzoyloxy-2-azetidinone | Combi-Blocks | 28562-58-5 | MFCD00012317 | 191.186 | C10H9NO3 | 97.000 | O=C(OC1CC(=O)N1)c1ccccc1 | 1g | 267200512
eMolecules 17557-84-5 | 3-Azetidinone Hydrochloride | Accela ChemBio (ASD) | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 588340315
3-Azetidinone Hydrochloride | Accela ChemBio (ASD) | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 588340315
eMolecules 17557-84-5 | 3-Azetidinone HCl | Ambeed | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 570568402
3-Azetidinone HCl | Ambeed | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 25g | 570568402
eMolecules 17557-84-5 | 3-Azetidinone hydrochloride | Synthonix - Stock | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 1g | 525905203
3-Azetidinone hydrochloride | Synthonix - Stock | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 97.000 | Cl.O=C1CNC1 | 1g | 525905203
eMolecules 17557-84-5 | Azetidin-3-one hydrochloride | AA Blocks LLC | MFCD01861742 | 107.540 | C3H6ClNO | 0.000 | Cl.O=C1CNC1 | 250mg | 779494524
Azetidin-3-one hydrochloride | AA Blocks LLC | 17557-84-5 | MFCD01861742 | 107.540 | C3H6ClNO | 0.000 | Cl.O=C1CNC1 | 250mg | 779494524
Medchemexpress LLC Thalidomide 4-fluoride (Cereblon ligand 4) | 835616-60-9 | 99.83% | 276.22 | 25 G
Thalidomide 4-fluoride (Cereblon ligand 4) is a Thalidomide-based Cereblon ligand that is utilized in the recruitment of the CRBN protein. It can be linked to the ligand for IRAK4 protein via a linker to form PROTAC IRAK4 degrader-1. It is for research use only and not sold to patients.
- Purity: 99.83%
- Molecular weight: 276.22
- Formula: C13H9FN2O4
- CAS No.: 835616-60-9
- Appearance: Solid
- Color: Off-white to gray
- Solubility (in vitro): DMSO : 200 mg/mL (724.05 mM; requires ultrasonic; hygroscopic DMSO impacts solubility, use newly opened DMSO)
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 2 years, -20°C for 1 year
Medchemexpress LLC Thalidomide-5-OH | 64567-60-8 | 98.2% | 274.23 | 25 G
Thalidomide-5-OH is a thalidomide-based cereblon ligand. It is used in the recruitment of CRBN protein and can be connected to a target protein ligand via a linker to form PROTACs.
- Thalidomide-based cereblon ligand
- Recruits CRBN protein
- Connects to protein ligands via a linker to form PROTACs
- Targets cereblon
Medchemexpress LLC Thalidomide-PEG2-C2-NH2 (hydrochloride) | 2245697-87-2 | >99.9% | 100 MG
Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a 2-unit PEG linker used in PROTAC technology. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in PROTAC technology.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
- Incorporates thalidomide based cereblon ligand.
- Features a 2-unit PEG linker.
- For research use only.
Medchemexpress LLC Thalidomide-4-Br | 2093536-12-8 | MFCD31730866 | 99.6% | 337.13 g·mol⁻¹ | C13H9BrN2O4 | 200 MG
Thalidomide-4-Br is a brominated thalidomide derivative used as a research compound that engages bromodomains and cereblon-related E3 ligase biology. It is applied in studies of inflammation, tumor biology, and neurology and is supplied as a high-purity solid with recommended cold storage for powder and solutions.
- Engages bromodomains and E3 ligase pathways.
- Used in inflammation, tumor, and neurology research.
- Reported purity approximately 99.6% (COA/product listings).
- Solid, off-white to gray physical form.
- Storage: powder at -20°C (long term) or 4°C (short term); solutions at -80°C or -20°C.
- Available in small-scale amounts and DMSO solution formats.
Medchemexpress LLC Thalidomide-5-O-C13-NH2 (hydrochloride) | 99.9% | 508.05 | 5 MG
Thalidomide-5-O-C13-NH2 hydrochloride is a cereblon ligand based on Thalidomide. It is utilized in the recruitment of CRBN protein and can be connected to a protein ligand by a linker to form PROTACs.
- Cereblon ligand
- Used in the recruitment of CRBN protein
- Can be connected to a protein ligand by a linker
- Forms PROTACs
Medchemexpress LLC Thalidomide-O-C6-COOH | 2169266-69-5 | 99.3% | 100 MG
Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates a Thalidomide-based cereblon ligand and a linker, designed for use in PROTAC technology. PROTACs function by connecting two ligands: one for an E3 ubiquitin ligase and another for a target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system. This product is intended for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide based cereblon ligand
- Designed for PROTAC technology applications
- Selectively degrades target proteins via ubiquitin-proteasome system
- Off-white to light yellow solid
- Soluble in DMSO at ≥ 100 mg/mL
Medchemexpress LLC Thalidomide-4-Br | 2093536-12-8 | MFCD31730866 | 99.6% | 337.13 | C13H9BrN2O4 | 50 MG
Thalidomide-4-Br is a brominated thalidomide derivative used as a cereblon/bromodomain ligand in preclinical research on inflammation, oncology, and neurology. It is supplied as a solid, off-white to gray powder with characterized identity and stability data.
- High purity (reported ≈99.6%).
- Well characterized: CAS 2093536-12-8; formula C13H9BrN2O4; molecular weight 337.13.
- Available in multiple package sizes, including small (50 mg) and larger quantities.
- Defined storage and stability: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Suitable for cereblon-targeting studies and use as a ligand in PROTAC development.