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Lactims

Organic heterocyclic compounds that consist of a cyclic carboximidic acid characterized by a carbon-nitrogen double bond within the ring; they are tautomeric with the lactams.
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1

Glutarimide 98.0+%, TCI America™

CAS: 1121-89-7 Molecular Formula: C5H7NO2 Molecular Weight (g/mol): 113.12 MDL Number: MFCD00006670 InChI Key: KNCYXPMJDCCGSJ-UHFFFAOYSA-N Synonym: glutarimide,2,6-piperidinedione,2,6-diketopiperidine,2,6-dioxopiperidine,acetylglycinamide impurity b,piperidin-2,6-dione,acmc-2099da,5-21-09-00557 beilstein handbook reference,2,6-piperidinedione 9ci PubChem CID: 70726 ChEBI: CHEBI:5435 IUPAC Name: piperidine-2,6-dione SMILES: O=C1CCCC(=O)N1

PubChem CID 70726
CAS 1121-89-7
Molecular Weight (g/mol) 113.12
ChEBI CHEBI:5435
MDL Number MFCD00006670
SMILES O=C1CCCC(=O)N1
Synonym glutarimide,2,6-piperidinedione,2,6-diketopiperidine,2,6-dioxopiperidine,acetylglycinamide impurity b,piperidin-2,6-dione,acmc-2099da,5-21-09-00557 beilstein handbook reference,2,6-piperidinedione 9ci
IUPAC Name piperidine-2,6-dione
InChI Key KNCYXPMJDCCGSJ-UHFFFAOYSA-N
Molecular Formula C5H7NO2
2

DL-Aminoglutethimide 98.0+%, TCI America™

CAS: 125-84-8 Molecular Formula: C13H16N2O2 Molecular Weight (g/mol): 232.283 MDL Number: MFCD00010122 InChI Key: ROBVIMPUHSLWNV-UHFFFAOYSA-N Synonym: aminoglutethimide,dl-aminoglutethimide,cytadren,orimeten,p-aminoglutethimide,elipten,3-4-aminophenyl-3-ethylpiperidine-2,6-dione,aminoglutetimida,3-4-aminophenyl-3-ethyl-2,6-piperidinedione,aminoglutethimidum PubChem CID: 2145 ChEBI: CHEBI:2654 IUPAC Name: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione SMILES: CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N

PubChem CID 2145
CAS 125-84-8
Molecular Weight (g/mol) 232.283
ChEBI CHEBI:2654
MDL Number MFCD00010122
SMILES CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N
Synonym aminoglutethimide,dl-aminoglutethimide,cytadren,orimeten,p-aminoglutethimide,elipten,3-4-aminophenyl-3-ethylpiperidine-2,6-dione,aminoglutetimida,3-4-aminophenyl-3-ethyl-2,6-piperidinedione,aminoglutethimidum
IUPAC Name 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
InChI Key ROBVIMPUHSLWNV-UHFFFAOYSA-N
Molecular Formula C13H16N2O2
3

Medchemexpress LLC Dbm-C5-VC-PAB-MMAE | 1644228-55-6 | 99.5% | 1474.42 | C68H103Br2N11O15 | 10 MG
SDP

DBM-C5-VC-PAB-MMAE is a drug-linker conjugate used to construct antibody-drug conjugates (ADCs); it combines a C5-VC-PAB cleavable linker with a maleimide DBM attachment and the cytotoxic payload MMAE.

  • Drug-linker conjugate for ADC construction.
  • Purity 99.5%.
  • Molecular weight 1474.42.
  • Chemical formula C68H103Br2N11O15.
  • CAS number 1644228-55-6.
  • Supplied as 10 MG per package.

ENCOMPASS_PREFERRED
4

Medchemexpress LLC 6-(3,4-dibromo-2,5-dioxopyrrol-1-yl)hexanoic acid | 1443214-97-8 | MFCD09813286 | 99.4% | 369.01 g/mol | C10H11Br2NO4 | 50 MG
SDP

Dibromomaleimide-C5-COOH is a bifunctional dibromomaleimide linker used in antibody-drug conjugate synthesis to connect payloads such as MMAF. It is supplied as a white to off-white solid with high purity and is soluble in DMSO.

  • Bifunctional dibromomaleimide linker for ADC synthesis.
  • High purity (99.4%) suitable for research applications.
  • Molecular weight 369.01 g/mol and formula C10H11Br2NO4.
  • Soluble in DMSO at ≥100 mg/mL.
  • Available in small-scale quantities (5-200 mg) for conjugation workflows.
  • Store at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).

ENCOMPASS_PREFERRED
5

Medchemexpress LLC Borate, 5-[(3,5-dimethyl-2H-pyrrol-2-ylidene)methyl]-1H-pyrrole-2-pentanoato difluoro | 217075-24-6 | 99.7% | 320.14 g/mol | C16H19BF2N2O2 | 10 MG
SDP

BODIPY FL C5 is a green fluorescent fatty acid probe used for labeling lipids and membranes and as a precursor for synthesizing fluorescent phospholipids. It fluoresces in both aqueous and lipid environments and is supplied as an orange to red solid at high purity for research applications. Not for drug or household use.

  • High purity (99.7%).
  • Fluoresces in aqueous and lipid environments.
  • Suitable for membrane labeling and lipid trafficking assays.
  • Orange to red solid, easy to handle.
  • Supplied in 10 mg quantities for laboratory workflows.
  • Includes COA and SDS for quality and safety information.

ENCOMPASS_PREFERRED
6

Medchemexpress LLC 10-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)-4,7,13,16-tetraoxa-10-azanonadecanedioic acid | 3026691-12-0 | 98.0% | 530.57 g·mol-1 | C24H38N2O11 | 50mg
SDP

Mal-C5-N-bis(PEG2-C2-acid) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]

ENCOMPASS_PREFERRED
7

Medchemexpress LLC (S,R,S)-AHPC-C5-NH2 dihydrochloride | 2415256-20-9 | 97.8% | 616.64 | 25 MG
SDP

(S,R,S)-AHPC-C5-NH2 dihydrochloride is a chemical compound with a molecular weight of 616.64. It appears as an off-white to light yellow solid and is suitable for research applications. This product is for research use only and has not been fully validated for medical applications.

  • Chemical name: (2S,4R)-1-((S)-2-(6-Aminohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
  • CAS number: 2415256-20-9
  • Molecular formula: C28H43Cl2N5O4S
  • Molecular weight: 616.64
  • Purity: 97.8% (HPLC)
  • Appearance: Off-white to light yellow solid
  • Storage: -20°C, sealed storage, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month, sealed storage, away from moisture.

ENCOMPASS_PREFERRED
8

Medchemexpress LLC Glutarimide-Isoindolinone-NH-PEG2-COOH | 2803827-03-2 | 98.5% | 419.43 | 50 MG
SDP

Glutarimide-Isoindolinone-NH-PEG2-COOH is a chemical compound with the molecular formula C20H25N3O7 and a molecular weight of 419.43. It demonstrates high purity, verified at 98.51% by LCMS.

  • CAS Number: 2803827-03-2
  • Molecular formula: C20H25N3O7
  • Molecular weight: 419.43
  • Purity: 98.51% (LCMS)
  • Store at -20°C, protected from light
  • Store in solvent at -80°C for 6 months, or -20°C for 1 month (protected from light)

ENCOMPASS_PREFERRED
9

Medchemexpress LLC (S,R,S)-AHPC-C5-NH2 dihydrochloride | 2415256-20-9 | 97.8% | C28H43Cl2N5O4S | 10MG
SDP

(S,R,S)-AHPC-C5-NH2 dihydrochloride is a VHL ligand-linker conjugate supplied as the dihydrochloride salt for use as a PROTAC building block in research. It contains a C5 linker terminating in a primary amine and is provided as a solid intended for laboratory synthesis and biological studies.

  • Purity 97.8%.
  • Off-white to light yellow solid appearance.
  • Chemical formula C28H43Cl2N5O4S.
  • Molecular weight 616.64 g/mol.
  • Recommended storage: -20°C, sealed and away from moisture.
  • In solvent stability: -80°C for 6 months; -20°C for 1 month.
  • For research use only; not for human use.

ENCOMPASS_PREFERRED
10

Medchemexpress LLC (S,R,S)-AHPC-C5-NH2 dihydrochloride | 2415256-20-9 | 97.8% | 616.64 g/mol | C28H43Cl2N5O4S | 5 MG
SDP

(S,R,S)-AHPC-C5-NH2 dihydrochloride is the dihydrochloride salt of an AHPC-derived E3 ligase ligand, provided as a solid for research use in studies of VHL E3 ubiquitin ligase recruitment and targeted protein degradation.

  • Dihydrochloride salt form for improved stability.
  • High purity of 97.8%.
  • Molecular weight 616.64 g/mol.
  • Molecular formula C28H43Cl2N5O4S.
  • Suitable as an E3 ligase ligand-linker component in PROTAC designs.
  • Storage: sealed, away from moisture; in solvent: -80°C up to 6 months, -20°C up to 1 month.
  • Documentation available: datasheet, COA, SDS.

ENCOMPASS_PREFERRED
11

MilliporeSigma™ Cycloheximide, ≥90%, Calbiochem™,

CAS: 66-81-9 Molecular Formula: C15H23NO4 Molecular Weight (g/mol): 281.35 MDL Number: MFCD00082346 InChI Key: YPHMISFOHDHNIV-QTEFRXOUNA-N Synonym: cycloheximide,actidione,cycloheximide,naramycin a,kaken,actidion,actidone,hizarocin,naramycin,neocycloheximide PubChem CID: 6197 ChEBI: CHEBI:27641 IUPAC Name: 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione SMILES: [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1

PubChem CID 6197
CAS 66-81-9
Molecular Weight (g/mol) 281.35
ChEBI CHEBI:27641
MDL Number MFCD00082346
SMILES [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1
Synonym cycloheximide,actidione,cycloheximide,naramycin a,kaken,actidion,actidone,hizarocin,naramycin,neocycloheximide
IUPAC Name 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
InChI Key YPHMISFOHDHNIV-QTEFRXOUNA-N
Molecular Formula C15H23NO4