Lactones
AdipoGen Butyrolactone I
Chemical. CAS 87414-49-1. Formula C24H24O7. MW 424.5. Isolated from Aspergillus terreus. Cell permeable, potent and selective cyclin-dependent kinase CDK-1 CDC2, -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone. Important probe for understanding the cellular roles of CDKs. Inhibitor of alpha-glucosidases. Maturation inhibitor of sheep oocytes.
AdipoGen Butyrolactone I
Chemical. CAS 87414-49-1. Formula C24H24O7. MW 424.5. Isolated from Aspergillus terreus. Cell permeable, potent and selective cyclin-dependent kinase CDK-1 CDC2, -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone. Important probe for understanding the cellular roles of CDKs. Inhibitor of alpha-glucosidases. Maturation inhibitor of sheep oocytes.
AdipoGen Butyrolactone II
Chemical. CAS 87414-44-6. Formula C19H16O7. MW 356.3. Isolated from Aspergillus sp. Antibiotic. Weak cytotoxic towards bacterial and cancer cell lines. 5-Lipoxygenase 5-LOX inhibitor. Shows DPPH 2,2-diphenyl-1-picrylhydrazyl radical-scavening activity.
![eMolecules 1353016-70-2 | 11,12-Didehydro-gamma-oxodibenzo[b,f]azocine-5(6H)-butanoic acid | Synthonix | MFCD28064336 | 305.333 | C19H15NO3 | 95.000 | OC(=O)CCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 5g | 808304675](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000224084.jpg-250.jpg)
eMolecules 1353016-70-2 | 11,12-Didehydro-gamma-oxodibenzo[b,f]azocine-5(6H)-butanoic acid | Synthonix | MFCD28064336 | 305.333 | C19H15NO3 | 95.000 | OC(=O)CCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 5g | 808304675
11,12-Didehydro-gamma-oxodibenzo[b,f]azocine-5(6H)-butanoic acid | Synthonix | 1353016-70-2 | MFCD28064336 | 305.333 | C19H15NO3 | 95.000 | OC(=O)CCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 5g | 808304675
Selleck Chemical LLC ATN-161
ATN-161 is a novel small peptide antagonist of integrin 5 1 It binds to several integrins including 5 1 and v 3 that play a role in angiogenesis and tumor progression
Medchemexpress LLC 5-methyldihydrofuran-2(3H)-one (gamma-valerolactone) | 108-29-2 | MFCD00005400 | 99.9% | 100.12 g/mol | C5H8O2 | 100 G
Gamma-valerolactone (5-methyldihydrofuran-2(3H)-one) is a colorless to light yellow liquid lactone used as a biochemical reagent and analytical reference standard for life-science and analytical applications. It has molecular formula C5H8O2, molecular weight 100.12 g/mol, and CAS 108-29-2. Intended for research use only.
- High purity suitable for analytical applications.
- Colorless to light yellow liquid with density ~1.05 g/cm3.
- Versatile solvent and reagent for organic synthesis and analysis.
- Commonly used as an analytical reference standard.
- Stable under recommended storage conditions for extended shelf life.
Medchemexpress LLC Beta-propiolactone | 57-57-8 | MFCD00005169 | 99.4% | 72.06 g/mol | C3H4O2 | 500 MG
Propiolactone (beta-propiolactone) is a small cyclic ester used in laboratory research as a chemical viral inactivator and analytical reagent. Supplied as a high-purity liquid, it is used for virus inactivation, preparation of analytical standards, and other controlled research applications and must be handled with appropriate safety precautions.
- High purity (≈99.4%).
- Molecular weight 72.06 g/mol.
- Colorless to light yellow liquid with density ~1.1460 g/cm3.
- Available in multiple pack sizes, including 500 mg.
- Storage: pure form -20 °C; in solvent -80 °C (short term).
- Used as a viral inactivator and analytical standard in research settings.
- For research use only; not for human or clinical use.
Pfaltz & Bauer Pilocarpine hydrochloride 99% 1G | 54-71-7
Pilocarpine hydrochloride 99% 1G | 54-71-7
Medchemexpress LLC Butyrolactone I (olomoucin) | 87414-49-1 | MFCD03453074 | 99.8% | 424.44 | C24H24O7 | 5 MG
Butyrolactone I (olomoucin) is an orally active, ATP-competitive cyclin-dependent kinase 1 (CDK1) inhibitor used in preclinical research to study cell-cycle regulation, apoptosis, and inflammatory signaling. It has reported activity against NF-κB and PERK/CHOP pathways and is commonly used in cancer and metabolic disease research.
- ATP-competitive CDK1 inhibitor
- Reported modulation of NF-κB, PERK/CHOP, and apoptosis pathways
- High purity suitable for research applications
- Molecular formula C24H24O7; molecular weight 424.44
- Soluble in DMSO; ultrasonic assistance recommended
- Store protected from light; follow supplier solvent storage guidance
Medchemexpress LLC β-propiolactone | 57-57-8 | MFCD00005169 | 99.4% | 72.06 g·mol⁻¹ | C3H4O2 | 100 MG
Propiolactone (β-propiolactone) is a reactive four-membered lactone used as a chemical viral inactivator and research reagent. It is supplied for analytical and inactivation applications and is intended for research use only, not for human or clinical use.
- High purity (99.36%).
- Molecular weight 72.06 g·mol⁻¹.
- Molecular formula C3H4O2.
- Synonyms include β-propiolactone and 2-oxetanone.
- Available as a liquid 100 MG and as a 10 mM solution (1 mL) in DMSO.
- Storage: pure -20°C up to 3 years; in solvent -80°C for 6 months or -20°C for 1 month.
- Intended for laboratory research; controlled-substance restrictions may apply in some territories.
Sigma Aldrich Fine Chemicals Biosciences Pilocarpine hydrochloride >=99% (titration), powder | 54-71-7 | MFCD00012722 | 10G
Pilocarpine hydrochloride >=99% (titration), powder | Purity: >=99% (titration) | Mol Wt: 244.72 | 54-71-7 | MFCD00012722 | 10G