Lactones
![eMolecules 622381-67-3 | tert-Butyl 4-[4-(hydroxymethyl)benzyl]tetrahydro-1(2H)-pyrazinecarboxylate | Combi-Blocks, Inc. | MFCD06658975 | 306.406 | C17H26N2O3 | 95.000 | CC(C)(C)OC(=O)N1CCN(Cc2ccc(CO)cc2)CC1 | 25g | 801110543](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000473466.jpg-250.jpg)
eMolecules 622381-67-3 | tert-Butyl 4-[4-(hydroxymethyl)benzyl]tetrahydro-1(2H)-pyrazinecarboxylate | Combi-Blocks, Inc. | MFCD06658975 | 306.406 | C17H26N2O3 | 95.000 | CC(C)(C)OC(=O)N1CCN(Cc2ccc(CO)cc2)CC1 | 25g | 801110543
tert-Butyl 4-[4-(hydroxymethyl)benzyl]tetrahydro-1(2H)-pyrazinecarboxylate | Combi-Blocks, Inc. | 622381-67-3 | MFCD06658975 | 306.406 | C17H26N2O3 | 95.000 | CC(C)(C)OC(=O)N1CCN(Cc2ccc(CO)cc2)CC1 | 25g | 801110543
![Medchemexpress LLC N-[3-chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]-methanesulfon... | 1621175-65-2 | MFCD30182283 | 99.4% | 418.90 g/mol | C18H19ClN6O2S | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000246933.png-250.jpg)
Medchemexpress LLC N-[3-chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]-methanesulfon... | 1621175-65-2 | MFCD30182283 | 99.4% | 418.90 g/mol | C18H19ClN6O2S | 1 ML
TC-G-1008 (GPR39-C3) is a potent, orally available agonist of the GPR39 zinc-sensing G protein-coupled receptor, exhibiting EC50 values of 0.4 nM (rat) and 0.8 nM (human) and commonly used in in vitro and in vivo pharmacology studies.
- Potent GPR39 agonist (EC50 0.4 nM rat, 0.8 nM human).
- Orally available and active in in vivo models.
- Available as 10 mM solution in DMSO (1 mL) or solid quantities.
- Molecular formula C18H19ClN6O2S; molecular weight 418.90 g/mol.
- Reported purity 99.4% (HPLC).
- Intended for research use in pharmacology and metabolic studies.
Medchemexpress LLC Fc gamma RIIA (CD32a) recombinant human Fc-fusion protein, H167R | 9000-83-3 | 50 UG
Recombinant human Fc gamma RIIA (CD32a) Fc-fusion protein, H167R variant, produced in HEK293 cells. Intended for biochemical and cell-based studies of antibody Fc interactions and receptor binding; provided as a recombinant extracellular domain fused to a human Fc to improve stability and detection.
- Recombinant human extracellular domain with H167R mutation for functional assays.
- HEK293 expression ensures mammalian glycosylation and proper folding.
- C-terminal human Fc fusion increases stability and simplifies detection.
- Suitable for receptor binding, SPR, ELISA, and cell-based assays.
- Provided in a research-grade recombinant protein format for in vitro studies.
Medchemexpress LLC Gamma-secretase modulator 6 | 1255700-88-9 | 99.7% | 442.51 | 1 ML
gamma-secretase modulator 6 (Example 50) is a gamma-secretase modulator. It inhibits Aβ42 secretion in HEK cell line stably expressing APP (Aβ amyloid precursor protein) (pIC50: 8.1), making it suitable for research.
- Used for research of Alzheimer's disease
- Inhibits Aβ42 secretion in HEK cell lines stably expressing APP
Medchemexpress LLC gamma-Secretase Modulators | 937812-80-1 | 99.8% | C26H24F3N3O3 | 1 MG
This product, also known as Amyloid-β production inhibitor, is useful for Alzheimer's disease research. It is a solid appearing white to off-white and acts as a γ-secretase modulator.
- Useful for Alzheimer's disease research
- Targets γ-secretase modulator
- Solid with a white to off-white appearance
- Shipped at room temperature in continental US
- Store at 4°C under nitrogen
- In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
TARGETMOL CHEMICALS INC gamma-Linolenic acid 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg and bulk. Please contact Fisher for quotes. gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown gamma-Linolenic Acid to have induced reactive oxygen species generation including lipid peroxidation, cell growth inhibition, and heme oxygenase-1 production for antioxidant protection against oxidative stress. Further experiments have noted that gamma-Linolenic acid inhibits inflammatory responses through inactivation of NFkB and activator protein-1 by suppressed oxidative stress. Purity 99.21%
Medchemexpress LLC Fc gamma RIIA/CD32a 100ug | 100ug
Fc gamma The RIIA/CD32a protein plays a key role as a low-affinity receptor that specifically binds to the Fc region of immunoglobulin gamma It interacts with IgG to initiate cellular responses against pathogens which is critical for immune regulation Fc gamma RIIA/CD32a Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived Fc gamma RIIA/CD32a protein expressed by HEK293 with C-Avi C-His labeled tag and H167 mutation
Medchemexpress LLC SIRP gamma Cynomolg 100ug | 100ug
SIRP gamma Protein a member of signal-regulatory protein (SIRP) family is the only SIRP detected on T cells and activated NK cells SIRP gamma can bind CD47 providing T cells and NK cells with a cell surface molecule capable of interacting with CD47 SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion SIRP gamma Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived SIRP gamma protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) | ≥98.0% | Approximately 38 kDa (PRKAB1) & 40 kDa (PRKAG1) & 95 kDa (PRKAA1), based on SDS-PAGE under reducing conditions. | 5 UG
AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is a recombinant human-derived protein expressed by Sf9 insect cells with N-His and N-GST labeled tags. It functions as the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), a critical regulator of cellular energy metabolism. Activated by low ATP levels, AMPK enhances energy production while inhibiting biosynthetic processes and cell growth, thereby maintaining cellular energy homeostasis.
- Specific activity determined to be 53 nmol/min/mg
- Expressed in Sf9 insect cells
- N-His and N-GST labeled tags
- Purity greater than 98.0% by SDS-PAGE
- Endotoxin level less than 1 EU/μg
- Stable at -80°C for 1 year from receipt
- Formulated as a 0.22 μm filtered solution of 20 mM Tris, 300 mM NaCl, 10% glycerol, pH 7.5
- Approximate molecular weights: 38 kDa (PRKAB1), 40 kDa (PRKAG1), 95 kDa (PRKAA1)
Medchemexpress LLC Gamma Catenin Antibody (YA3801) | 82 kDa | 100 UL
Gamma Catenin Antibody (YA3801) | 82 kDa | 100 UL
Medchemexpress LLC Gamma-Mangostin | 31271-07-5 | 396.43 | 20 MG
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. It binds to thyroxine (T4)-binding sites and stabilizes the TTR tetramer. It possesses anti-inflammatory, antibacterial, antioxidant, and anticancer activities, and can be used in the study of metabolic disorders such as diabetes.
- Novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist
- Potent epoxidase 2 (COX-2) inhibitor
- Transthyroxin protein (TTR) profibrosis inhibitor
- Binds to thyroxine (T4)-binding sites and stabilizes the TTR tetramer
- Anti-inflammatory activity
- Antibacterial activity
- Antioxidant activity
- Anticancer activities
- Used in the study of metabolic disorders such as diabetes