Oxazinanes
Medchemexpress LLC Quisinostat (dihydrochloride) | 875320-31-3 | C21H28Cl2N6O2 | 25 MG
Quisinostat (dihydrochloride) | 875320-31-3 | C21H28Cl2N6O2 | 25 MG
TARGETMOL CHEMICALS INC Neboglamine hydrochloride 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Neboglamine (CR-2249, XY-2401) hydrochloride, an orally active positive modulator of the NMDA receptor glycine site, can be used in schizophrenia research [1]. Purity 99.11%
Selleck Chemical LLC Melitracen hydrochloride S5034-25mg
Melitracen hydrochloride (Thymeol) is a potential dopamine D1/2 receptor antagonist which has antidepressant properties
eMolecules Oakwood Chemical Ethanesulfonyl chloride 1g 537693039 044992 594-44-5 MFCD00007460 128.570 C2H5ClO2S
Oakwood Chemical Ethanesulfonyl chloride 1g 537693039 044992 594-44-5 MFCD00007460 128.570 C2H5ClO2S
Selleck Chemical LLC GPNA hydrochloride
GPNA hydrochloride (L- -glutamyl-p-nitroanilide hydrochloride) is a substrate of -glutamyltransferase (GGT) and an inhibitor of the glutamine transporter ASCT2 with an IC50 of 250 M in A549 cells It also inhibits Na -dependent carriers SNAT1 -2 -4 -5 and Na -independent leucine transporters LAT1/2 It can be widely used in research on pancreatic cancer breast cancer glioblastoma multiforme acute myelogenous leukemia and non-small-cell lung cancer
Medchemexpress LLC Pirenzepine dihydrochloride | 29868-97-1 | 99.8% | 424.32 | 1 G
Pirenzepine dihydrochloride is a selective M1 muscarinic acetylcholine receptor antagonist that poorly penetrates the blood-brain barrier. It is used in peptic ulcer research due to its ability to reduce gastric acid secretion and muscle spasm. This compound also exhibits anti-proliferative activity against cancer cells.
- Selective M1 muscarinic acetylcholine receptor antagonist.
- Reduces gastric acid secretion.
- Reduces muscle spasm.
- Useful in peptic ulcer research.
- Exhibits anti-proliferative activity against cancer cells.
Selleck Chemical LLC TCEP Hydrochloride S4611-1g
TCEP (Tris(2-carboxyethyl)phosphine) hydrochloride a non-thiol reducing agent promotes NF- B-DNA binding in a dose-related manner Solutions are best fresh-prepared
Medchemexpress LLC 7,8-Dihydro-L-biopterin | 6779-87-9 | 99.8% | 239.23 | 50 MG
7,8-Dihydro-L-biopterin | 6779-87-9 | 99.8% | 239.23 | 50 MG
Medchemexpress LLC Isoquinoline, 3,4-dihydro-1-phenyl- | 52250-50-7 | MFCD00006760 | ≥96.0% | 207.28 | 10 G
1-Phenyl-3,4-dihydroisoquinoline is a chemical reagent. It has a molecular weight of 207.28 and typically appears as a light yellow to brown liquid. This product is suitable for various laboratory applications.
- Purity of at least 96.0%
- Molecular weight of 207.28 g/mol
- Appears as a light yellow to brown liquid
TARGETMOL CHEMICALS INC A 77636 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. A 77636 hydrochloride is a potent orally active selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionally inactive at dopamine D2 receptor. purity: 99%
Medchemexpress LLC Elacestrant dihydrochloride | 1349723-93-8 | 99.5% | 531.56 | 50 MG
Elacestrant dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) that can inhibit the growth of ER+ breast cancer cell lines in vitro and in vivo. It is effective against ERα and ERβ, making it suitable for research into hormone receptor-positive breast cancers.
- Orally available and selective estrogen receptor degrader (SERD)
- Inhibits the growth of ER+ breast cancer cell lines in vitro and in vivo
- Effective against ERα and ERβ targets
- Suitable for various research applications in breast cancer studies
Medchemexpress LLC Chloroquine (dihydrochloride) | 3545-67-3 | MFCD06804666 | 99.6% | 392.79 g/mol | C18H28Cl3N3 | 10 MG
Chloroquine (dihydrochloride) is the dihydrochloride salt of chloroquine, a 4-aminoquinoline antimalarial and anti-inflammatory agent used as a research reagent. It is commonly used to inhibit autophagy, alter endosomal/lysosomal pH, and as a screening compound in antiviral and antiparasitic assays.
- High chemical purity suitable for research (reported ~99.6%).
- Solid form suitable for formulation or solution preparation.
- Commonly used as an autophagy inhibitor in cell biology experiments.
- Modulates endosomal and lysosomal pH for trafficking and uptake studies.
- Available in small pack sizes for screening and assay workflows.
Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 200 MG
Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor, with IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3 respectively. It demonstrates potent efficacy in xenograft models where Akt is activated due to genetic alterations, leading to tumor growth delay, stasis, or regression. This compound is intended for research use only.
- Highly selective and ATP-competitive pan-Akt inhibitor.
- IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3.
- Significant selectivity for Akt1 compared to closely related kinases.
- Effective in xenograft models with Akt activation due to genetic alterations.
- Induces tumor growth delay, stasis, or regression in vivo.
- Enhances tumor regression and stasis when used in combination therapies.
- Increases tumor growth inhibition in ovarian cancer models when combined with other agents.
Medchemexpress LLC Prexasertib (dihydrochloride) | 1234015-54-3 | 99.4% | 438.31 | 1 ML
Prexasertib dihydrochloride is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. It causes double-stranded DNA breakage and replication catastrophe, leading to apoptosis, and exhibits potent anti-tumor activity. It also inhibits CHK2 and RSK1.
- Selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor.
- Causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis.
- Shows potent anti-tumor activity.
- Inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM).
TARGETMOL CHEMICALS INC ABEPRAZAN HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity inhibiting H+ K+ -atPase by competitive binding to potassium ions without acid activation. Abeprazan hydrochloride is a proton pump inhibitor (PPI) that acts by reducing gastric acid production and is used to treat gastric acid-related disorders such as gastroesophageal reflux disease (GERD) and peptic ulcers. purity: 98%