Oxazinanes
Cayman Chemical SKF 96365 hydrochloride
Inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels (IC50 = 10 µM); inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 µM
TARGETMOL CHEMICALS INC S-ERSO 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. (S)-ErSO is an inactive dextrorotatory enantiomer of ErSO. purity: 97%
eMolecules 1916-59-2 | 2-Amino-3h-phenoxazin-3-one | Combi-Blocks | MFCD00207317 | 212.208 | C12H8N2O2 | 97.000 | Nc1cc2nc3ccccc3oc2cc1=O | 1g | 439374819
2-Amino-3h-phenoxazin-3-one | Combi-Blocks | 1916-59-2 | MFCD00207317 | 212.208 | C12H8N2O2 | 97.000 | Nc1cc2nc3ccccc3oc2cc1=O | 1g | 439374819
Cayman Chemical PropenylLNIO hydrochloride
A potent, selective iNOS inhibitor (Kis = 17, 10.3 and 58.2 µM for iNOS, nNOS, and eNOS, respectively, for initial rate binding kinetics); demonstrates reversible tight binding inhibition that is selective for iNOS over nNOS (Kis = 0.56 and 6 µM, respectively)
TARGETMOL CHEMICALS INC DP-1 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DP-1 hydrochloride is a degradation product of SDC-TRAP-0063 a fragment of Ganetespib a heat shock protein 90 (HSP90) inhibitor with antitumor activity. purity: 99%
Apexbio Technology LLC GW311616 hydrochloride 197890-44-1 10mM (in 1mL DMSO)
GW311616 hydrochloride (CAS 197890-44-1) is a selective cell-permeable inhibitor of human neutrophil elastase (HNE) exhibiting an IC50 of 22 nM and a Ki of 0 13 nM in enzymatic assays It demonstrates pronounced selectivity with IC50 values exceeding 100 M for trypsin cathepsin G and plasmin and greater than 3 M for chymotrypsin and tissue plasminogen activator In human whole blood assays GW311616 hydrochloride achieves an IC50 of 0 67 M The compound is orally bioavailable and displays prolonged activity in dog blood samples indicating a sustained inhibitory effect on neutrophil elastase GW311616 hydrochloride is valuable for investigating HNE s role in inflammation and related pathologies
Medchemexpress LLC Quizartinib dihydrochloride | 1132827-21-4 | 99.8% | 633.59 g·mol⁻1 | C29H34Cl2N6O4S | 5 MG
Quizartinib dihydrochloride is the dihydrochloride salt form of quizartinib, a second-generation, highly selective type II FLT3 tyrosine kinase inhibitor used in preclinical oncology research. It demonstrates low-nanomolar potency against FLT3 and FLT3-ITD and is employed in cellular assays and medicinal chemistry applications, including degrader design. The material is supplied at research scale with high reported purity.
- High potency FLT3 inhibition in the low-nanomolar range.
- Suitable for in vitro and preclinical AML models.
- Compatible with PROTAC linker chemistry and conjugation studies.
- Supplied as the dihydrochloride salt for improved solubility.
- High purity suitable for biochemical and cellular assays.
- Available in multiple small research pack sizes.
Medchemexpress LLC AX-024 hydrochloride | 1704801-24-0 | 99.2% | 375.86 g/mol | C21H23ClFNO2 | 1 ML
AX-024 hydrochloride is a small-molecule inhibitor of the T cell receptor-Nck interaction that selectively inhibits TCR-triggered T cell activation. Supplied for research use in biochemical and cell-based assays, it is available as a 10 mM solution in DMSO (1 mL) or as solids for custom preparation.
- Selective inhibitor of TCR-Nck interaction for T cell signaling studies.
- High purity suitable for biochemical and cell-based assays.
- Provided as a 10 mM DMSO solution for ready-to-use experiments.
- Also available in multiple solid sizes for dosing flexibility.
- Store sealed at cold temperatures to preserve stability.
Medchemexpress LLC SP3N hydrochloride | 99.84% | 764.34 | 1 MG
SP3N hydrochloride is a specific degrader of the prolyl isomerase (FKBP12). The alkylamine of SP3N hydrochloride is metabolized to a reactive aldehyde (SP3CHO), which recruits the SCFFBXO22 ligase for FKBP12 degradation. SP3N hydrochloride may be used in research for cancer.
- Specific degrader of FKBP12.
- Metabolized to a reactive aldehyde (SP3CHO) which recruits SCFFBXO22 ligase for FKBP12 degradation.
- May be used in research for cancer.
![eMolecules 6857-34-7 | 4-Phenyl-1,3-dihydro-2H-imidazole-2-thione | Oakwood Chemical | MFCD10586461 | 176.240 | C9H8N2S | 97.000 | S=c1[nH]cc([nH]1)-c1ccccc1 | 1g | 537722183](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502151376.JPG-250.jpg)
eMolecules 6857-34-7 | 4-Phenyl-1,3-dihydro-2H-imidazole-2-thione | Oakwood Chemical | MFCD10586461 | 176.240 | C9H8N2S | 97.000 | S=c1[nH]cc([nH]1)-c1ccccc1 | 1g | 537722183
4-Phenyl-1,3-dihydro-2H-imidazole-2-thione | Oakwood Chemical | 6857-34-7 | MFCD10586461 | 176.240 | C9H8N2S | 97.000 | S=c1[nH]cc([nH]1)-c1ccccc1 | 1g | 537722183
![eMolecules 95408-45-0 | 1,1'-Bis(di-tert-butylphosphino) ferrocene palladium chloride | Oakwood Chemicals | MFCD08064219 | 651.750 | C26H44Cl2FeP2Pd | 98.000 | [Cl-].[Cl-].[Fe].[Pd++].CC(C)(C)P(c1cccc1)C(C)(C)C.CC(C)(C)P(c1cccc1)C(C)(C)C | 250mg | 480131028](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000130623.jpg-250.jpg)
eMolecules 95408-45-0 | 1,1'-Bis(di-tert-butylphosphino) ferrocene palladium chloride | Oakwood Chemicals | MFCD08064219 | 651.750 | C26H44Cl2FeP2Pd | 98.000 | [Cl-].[Cl-].[Fe].[Pd++].CC(C)(C)P(c1cccc1)C(C)(C)C.CC(C)(C)P(c1cccc1)C(C)(C)C | 250mg | 480131028
1,1'-Bis(di-tert-butylphosphino) ferrocene palladium chloride | Oakwood Chemicals | 95408-45-0 | MFCD08064219 | 651.750 | C26H44Cl2FeP2Pd | 98.000 | [Cl-].[Cl-].[Fe].[Pd++].CC(C)(C)P(c1cccc1)C(C)(C)C.CC(C)(C)P(c1cccc1)C(C)(C)C | 250mg | 480131028
Selleck Chemical LLC SB 271046 hydrochloride S2856-10mg
SB 271046 hydrochloride is a potent selective and orally active 5-HT6 receptor antagonist with pKi of 8 9 exhibits 200-fold greater selectivity over other 5-HT receptor subtypes
Selleck Chemical LLC OTS514 hydrochloride
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2 6 nM OTS514 induces cell cycle arrest and apoptosis
eMolecules ChemBridge - BB 2-cyclohexen-1-amine 5g 337748446 4075151 95.000 1541-25-9 MFCD02094002 97.161 C6H11N
ChemBridge - BB 2-cyclohexen-1-amine 5g 337748446 4075151 95.000 1541-25-9 MFCD02094002 97.161 C6H11N
![eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 5g | 773120108](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000474146.jpg-250.jpg)
eMolecules 16681-67-7 | 4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 5g | 773120108
4-Bromo-2-methyl-2H-[1,2,3]triazole | J&W PharmLab LLC | 16681-67-7 | MFCD23378485 | 161.990 | C3H4BrN3 | 96.000 | Cn1ncc(Br)n1 | 5g | 773120108