Oxazinanes
TARGETMOL CHEMICALS INC PD0166285 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator. purity: 99%
TARGETMOL CHEMICALS INC Pivmecillinam hydrochloride
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic effective against gram-negative organisms, and is used as a substitute for amdinocillin. Purity 99.86%
TARGETMOL CHEMICALS INC Palonosetron hydrochloride
Also available in 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Palonosetron hydrochloride (RS 25259) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting. Purity 99.97%
TARGETMOL CHEMICALS INC Bendamustine hydrochloride
Also available in 1 mL, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Bendamustine hydrochloride (EP-3101) (IC50 of 50 uM) is an alkylating agent associated with DNA damage. Purity 98.03%
TARGETMOL CHEMICALS INC Atomoxetine hydrochloride
Also available in 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels. Purity 99.8%
Sigma Aldrich Fine Chemicals Biosciences Aprepitant >=98% (HPLC) | 170729-80-3 | MFCD12912491 | 5MG
Aprepitant >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 534.43 | 170729-80-3 | MFCD12912491 | 5MG
TARGETMOL CHEMICALS INC CL-AMIDINE HYDROCHLORIDE 10MG
Also available in 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50 5.9 uM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro causing cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation. It improves survival in a murine sepsis model. purity: 98%
TARGETMOL CHEMICALS INC CSRM617 HYDROCHLORIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2 a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]purity: 99%