Oxazinanes
eMolecules 124-42-5 | Acetamidine hydrochloride | Oakwood Chemicals | MFCD00013016 | 94.540 | C2H7ClN2 | 92.000 | Cl.CC(N)=N | 500g | 480117564
Acetamidine hydrochloride | Oakwood Chemicals | 124-42-5 | MFCD00013016 | 94.540 | C2H7ClN2 | 92.000 | Cl.CC(N)=N | 500g | 480117564
eMolecules 6968-35-0 | 7-Hydroxy-2,3-dihydro-1H-inden-1-one | Synthonix - Stock | MFCD01548387 | 148.161 | C9H8O2 | 97.000 | Oc1cccc2CCC(=O)c12 | 1g | 459647420
7-Hydroxy-2,3-dihydro-1H-inden-1-one | Synthonix - Stock | 6968-35-0 | MFCD01548387 | 148.161 | C9H8O2 | 97.000 | Oc1cccc2CCC(=O)c12 | 1g | 459647420
Apexbio Technology LLC 5,6-Dihydro-UTP(Synonyms: 5,6-Dihydrouridine-5'-triphosphate, DHU-TP, 5,6-DHUTP, Dihydrouridine triphosphate), 50ul (100 mM).
5 6-Dihydro-UTP is a base-modified ribonucleoside triphosphate utilized in biochemical research Acting primarily as an acceptor substrate during enzymatic synthesis of dinucleoside polyphosphates this compound participates in phosphorylation reactions catalyzed by nucleotide-utilizing enzymes Due to its altered nucleobase structure 5 6-Dihydro-UTP serves as a strategic molecular probe in studies examining nucleotide synthesis pathways enzyme specificity and nucleic acid biochemistry
Chemscene ChemScene | 4-(Morpholino)phenylboronic acid | 10G | CS-W009091 | 0.98 | 186498-02-2| MFCD03095169 | 207.038
ChemScene | 4-(Morpholino)phenylboronic acid | 10G | CS-W009091 | 0.98 | 186498-02-2| MFCD03095169 | 207.038
eMolecules 445264-60-8 | 5-Methoxypyridine-3-boronic acid, pinacol ester | Combi-Blocks | MFCD03412068 | 235.090 | C12H18BNO3 | 98.000 | COc1cncc(c1)B1OC(C)(C)C(C)(C)O1 | 10g | 335349394
5-Methoxypyridine-3-boronic acid, pinacol ester | Combi-Blocks | 445264-60-8 | MFCD03412068 | 235.090 | C12H18BNO3 | 98.000 | COc1cncc(c1)B1OC(C)(C)C(C)(C)O1 | 10g | 335349394
eMolecules 109-11-5 | morpholin-3-one | Pharmablock | MFCD00631009 | 101.105 | C4H7NO2 | 97.000 | O=C1COCCN1 | 25g | 551071037
morpholin-3-one | Pharmablock | 109-11-5 | MFCD00631009 | 101.105 | C4H7NO2 | 97.000 | O=C1COCCN1 | 25g | 551071037
Apexbio Technology LLC PI-103 Hydrochloride 371935-79-4 10mM (in 1mL DMSO)
PI-103 Hydrochloride (CAS 371935-79-4) is a dual inhibitor targeting class I phosphatidylinositide 3-kinases (PI3K) and mammalian target of rapamycin (mTOR) It selectively inhibits PI3K isoforms p110 p110 p110 and mTOR with reported IC50 values of 0 002 M 0 003 M 0 003 M and 0 030 M respectively PI-103 effectively blocks the PI3K/Akt/mTOR pathway which is centrally involved in cell proliferation and survival signaling and is frequently dysregulated in cancer In various cellular models including leukemia hepatocellular carcinoma glioblastoma and neuroblastoma PI-103 suppresses pathway activation and inhibits cell proliferation It is widely used for investigating PI3K/Akt/mTOR signaling in oncology research
Apexbio Technology LLC SKF 525A (hydrochloride) 62-68-0 1g
SKF 525A (hydrochloride CAS 62-68-0) is a small-molecule inhibitor of cytochrome P450 (CYP) enzymes It modulates CYP-mediated metabolic pathways by inhibiting several isoforms including CYP2B6 CYP2C9 CYP2C19 CYP2D6 and CYP3A with limited impact on CYP1A2 CYP2A6 and CYP2E1 When assessed in human liver microsomes SKF 525A demonstrates CYP-dependent N-deethylation and exhibits inhibitory potency in the micromolar range In animal models it non-specifically disrupts sympathetic ganglia and adrenal medulla signaling possibly by stabilizing postsynaptic membranes SKF 525A is commonly used to study drug metabolism and CYP-mediated biotransformation in preclinical settings
Apexbio Technology LLC CBL0137 (hydrochloride) 1197397-89-9 2mg
CBL0137 (hydrochloride) (CAS 1197397-89-9) is a small-molecule curaxin that modulates transcriptional regulation by targeting the Facilitates Chromatin Transcription (FACT) complex This interaction leads to activation of p53 (EC50 0 37 M) and inhibition of NF- B signaling (EC50 0 47 M) pathways commonly dysregulated in cancer In vitro CBL0137 induces apoptosis in pancreatic cancer cell lines affecting both differentiated tumor cells and cancer stem cells In vivo studies demonstrate antitumor activity in models resistant to gemcitabine with additional combinatory effects attributed to transcriptional inhibition CBL0137 is under clinical evaluation in solid and hematological malignancies
TARGETMOL CHEMICALS INC Pioglitazone hydrochloride
Also available in 1 mL, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Purity 99.64%
TARGETMOL CHEMICALS INC Protriptyline hydrochloride
Also available in 1 mL, 10 mg, 25 mg and bulk. Please contact Fisher for quotes. Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. In addition, this agent exhibits anticholinergic activity. Purity 99.98%
Selleck Chemical LLC Nebivolol hydrochloride (R-65824) S1549-10mM/1mL
Nebivolol HCl (R-65824) selectively inhibits 1-adrenoceptor with IC50 of 0 8 nM
TARGETMOL CHEMICALS INC Etelcalcetide hydrochloride
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that serves as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively reducing parathyroid hormone (PTH) levels in patients with secondary hyperparathyroidism undergoing hemodialysis. Purity 100%
TARGETMOL CHEMICALS INC Coclaurine hydrochloride 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. (-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum. Purity 97.75%
TARGETMOL CHEMICALS INC Orphenadrine hydrochloride
Also available in 1 g, 1 mL, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. Purity 99.54%