Oxazinanes
c1ccccc1 | 0.25g | 302799645](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000165603.jpg-250.jpg)
eMolecules 1225376-02-2 | (R)-2-PHENYLMORPHOLINE | AstaTech | MFCD18249849 | 163.220 | C10H13NO | 95.000 | C1CO[C@@H](CN1)c1ccccc1 | 0.25g | 302799645
(R)-2-PHENYLMORPHOLINE | AstaTech | 1225376-02-2 | MFCD18249849 | 163.220 | C10H13NO | 95.000 | C1CO[C@@H](CN1)c1ccccc1 | 0.25g | 302799645
Selleck Chemical LLC Epertinib hydrochloride
Epertinib hydrochloride (S-222611 hydrochloride) is a potent orally active reversible and selective tyrosine kinase inhibitor of EGFR HER2 and HER4 with IC50 of 1 48 nM 7 15 nM and 2 49 nM respectively Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity
Selleck Chemical LLC Bobcat339 hydrochloride
Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 M and 73 M for TET1 and TET2 respectively Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe
Cayman Chemical Nefazodone hydrochloride
A serotonin, norepinephrine, and dopamine reuptake inhibitor (Kis = 137, 570, 2,380 nM, respectively); an antagonist of 5-HT2A, 5-HT1A, and histamine H1 receptors, as well as α1- and α2-ARs (Kis = 7.1, 52, 30, 5.5, and 84 nM, respectively); reduces immobility time in the tail suspension test in gerbils at 100 mg/kg; toxic to isolated human hepatocytes in a cultured sandwich hepatocyte preparation at 30 µM
Selleck Chemical LLC Harmine hydrochloride S3817-10mM/1mL
Harmine (Telepathine) a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A with about 60-fold higher IC50 value for DYRK2 Harmine also inhibits monoamine oxidases (MAOs) PPAR and cdc-like kinases (CLKs) Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM
Selleck Chemical LLC Ligustrazine hydrochloride S3775-25mg
Ligustrazine hydrochloride (Tetramethylpyrazine Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation antioxidant antiplatelet and antiapoptosis activities
TARGETMOL CHEMICALS INC Pioglitazone hydrochloride
Also available in 1 mL, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Purity 99.64%
TARGETMOL CHEMICALS INC Bendamustine hydrochloride
Also available in 1 mL, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Bendamustine hydrochloride (EP-3101) (IC50 of 50 uM) is an alkylating agent associated with DNA damage. Purity 98.03%
TARGETMOL CHEMICALS INC Atomoxetine hydrochloride
Also available in 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels. Purity 99.8%
Apexbio Technology LLC W-13 hydrochloride 88519-57-7 1mg
W-13 hydrochloride (CAS 88519-57-7) is a small molecule inhibitor that acts as an antagonist of calmodulin thereby modulating calmodulin-dependent signaling pathways and influencing intracellular calcium homeostasis Studies have demonstrated that W-13 hydrochloride suppresses the proliferation of human breast cancer cells resistant to tamoxifen indicating its utility in investigating mechanisms underlying cancer drug resistance This compound is widely employed in biomedical research to dissect calmodulin-mediated signaling and to explore pathways involved in the adaptive responses of tumor cells
Medchemexpress LLC ML-7 (hydrochloride) | 110448-33-4 | C15H18ClIN2O2S | 1 ML
ML-7 hydrochloride is a naphthalene sulphonamide derivative known for its potent inhibitory effects on Myosin Light Chain Kinase (MLCK) with an IC50 of 300 nM. It also acts as an inhibitor of YAP/TAZ. This compound is valuable for a range of in vitro and in vivo research applications, including studies on cellular contractility, gene transcription regulation, and neurological conditions.
- Potently inhibits MLCK (IC50=300 nM)
- Inhibits YAP/TAZ activity
- Supports various in vitro studies
- Applicable for in vivo research, such as brain injury models
- Provided as a ready-to-use solution
![eMolecules 136030-00-7 | (1R,2S)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL | AstaTech149.193 | C9H11NO | 95.000 | N[C@H]1[C@@H](O)Cc2ccccc12 | 1g | 718060126](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000163562.jpg-250.jpg)
eMolecules 136030-00-7 | (1R,2S)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL | AstaTech149.193 | C9H11NO | 95.000 | N[C@H]1[C@@H](O)Cc2ccccc12 | 1g | 718060126
(1R,2S)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL | AstaTech | 136030-00-7149.193 | C9H11NO | 95.000 | N[C@H]1[C@@H](O)Cc2ccccc12 | 1g | 718060126