Oxazinanes
TARGETMOL CHEMICALS INC TALIBEGRON HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Talibegron hydrochloride (ZD2079 hydrochloride) is an (beta)3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Relaxes rat mesenteric artery and isolated aorta in vitro. Inhibits ob gene expression and circulating leptin levels in lean mice in vivo. purity: 99%
TARGETMOL CHEMICALS INC PCI-34051 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PCI-34051 is an effective and selective HDAC8 inhibitor (IC50 10 nM). purity: 99%
eMolecules Synthonix (tert-Butyldimethylsilyloxy)acetaldehyde 250mg 649423879 B47208 0 000 102191-92-4 MFCD01321229 174 315 C8H18O2Si
Synthonix (tert-Butyldimethylsilyloxy)acetaldehyde 250mg 649423879 B47208 0 000 102191-92-4 MFCD01321229 174 315 C8H18O2Si
eMolecules ChemScene cis-Cyclohexane-12-diamine 25g 536839956 CS-M3552 1436-59-5 MFCD00063746 114.192 C6H14N2
ChemScene cis-Cyclohexane-12-diamine 25g 536839956 CS-M3552 1436-59-5 MFCD00063746 114.192 C6H14N2
TARGETMOL CHEMICALS INC Ruboxistaurin hydrochloride
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCbetaI and PKCbetaII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCbeta over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 uM for PKCη, -delta, -gamma, -alpha, - and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src). Purity 98.44%
eMolecules Ambeed 147-Triazonane trihydrochloride 25g 570567817 A145596 58966-93-1 MFCD00074887 238.580 C6H18Cl3N3
Ambeed 147-Triazonane trihydrochloride 25g 570567817 A145596 58966-93-1 MFCD00074887 238.580 C6H18Cl3N3
TARGETMOL CHEMICALS INC MRT 67307 DIHYDROCHLORID 5MG
Also available in 1 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MRT 67307 dihydrochloride is a dual inhibitor of the IKK(epsilon) and TBK-1 with IC50s of 160 and 19 nM respectively. MRT67307 dihydrochloride also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM respectively. MRT67307 dihydrochloride also blocks autophagy in cells. purity: 98%
AdipoGen CX-4945 HCl
Chemical. CAS 1009820-21-6 free acid. Formula C19H12ClN3O2 . HCl. MW 349.8 . 36.5. Synthetic. Orally active, potent and selective ATP-competitive inhibitor of the protein kinase CK2 IC50=1nM. Anticancer compound. Inhibits proliferation in a panel of cancer cell lines that overexpress CK2. Inhibited migration, blocks survival and induces apoptosis in cancer stem cells, glioblastomas and leukemia cells. Shown to decrease the glucose metabolism in cancer cells. Potent inhibitor of Cdc2-like kinases Clks in vitro, consequently interfering with alternative splicing. Potent ATP-competitive inhibitor of DYRK1A IC50=6.8 nM, involved in neurodegenration-associated diseases. CK2alpha deletion selectively increased M3 muscarinic receptors M3Rs-mediated insulin secretion from pancreatic islets. Promoted cAMP-induced thermogenesis in white adipocytes. CK2 inhibition ameliorates diet-induced obesity and insulin resistance in mice in vivo by promoting UCP1-dependent thermogenesis.
Medchemexpress LLC 6-Methyl-1 3-dihydro 10mg
6-Methyl-1 3-dihydrofuro[3 4-c]pyridin-7-ol hydrochloride is a Pyridoxine cyclic ether impurity
TARGETMOL CHEMICALS INC CLETOQUINE HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to against the chikungunya virus (CHIKV). Cletoquine hydrochloride exhibits antimalarial effects. purity: 98%
Medchemexpress LLC 8-bromotheophylline | 10381-75-6 | 99.3% | 259.06 g/mol | C7H7BrN4O2 | 250 MG
8-Bromotheophylline is a brominated theophylline derivative supplied for research and analytical applications and as a drug intermediate used in the synthesis of oxazolo[2,3-f]purinediones evaluated for adenosine receptor affinity.
- High purity of 99.3%.
- White to off-white solid appearance.
- Chemical formula C7H7BrN4O2; molecular weight 259.06 g/mol.
- Soluble in DMSO at 25 mg/mL; ultrasonic treatment recommended.
- Storage: store at 4°C sealed, away from moisture; in solution store at -80°C (6 months) or -20°C (1 month).
- Available in solid pack sizes including 250 mg.
Selleck Chemical LLC TRC102-E1503-250MG
TRC102 (methoxyamine hydrochloride O-Methylhydroxylamine hydrochloride) is a reagent used for the preparation of O-methyl oximes or the synthesis of O-methyl oximes from aldehydes
Apexbio Technology LLC DMG-PEG 2000 250mg
DMG-PEG 2000 can be used in the preparation of liposomes for siRNA delivery to enhance in vitro transfection efficiency It can also be employed in the formulation of lipid nanoparticles (LNP) to improve their mucus penetration and delivery efficiency as well as for oral plasmid DNA delivery methods in vivo
TARGETMOL CHEMICALS INC GSA-10 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 uM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling which may have research implications for regenerative medicine in cancer diseases. purity: 98%
TARGETMOL CHEMICALS INC DP-1 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DP-1 hydrochloride is a degradation product of SDC-TRAP-0063 a fragment of Ganetespib a heat shock protein 90 (HSP90) inhibitor with antitumor activity. purity: 99%