Piperidines
Accela Chembio Inc 1-boc-3-hydroxypiperidine | 25g | 85275-45-2 | MFCD02093938 | 97+% | Shelf Life: 1260 Days | Moisture Sensitive/+4
1-boc-3-hydroxypiperidine | 25g | 85275-45-2 | MFCD02093938 | 97+% | Shelf Life: 1260 Days | Moisture Sensitive/+4
![eMolecules 190446-85-6 | 1-PIPERIDINECARBOXYLIC ACID,4-[(HYDROXYIMINO)METHYL]-,1,1-DIMETHYLETHYL ESTER | AstaTech | MFCD11616948 | 228.292 | C11H20N2O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(CC1)\C=N\O | 1g | 268500283](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502180915.JPG-250.jpg)
eMolecules 190446-85-6 | 1-PIPERIDINECARBOXYLIC ACID,4-[(HYDROXYIMINO)METHYL]-,1,1-DIMETHYLETHYL ESTER | AstaTech | MFCD11616948 | 228.292 | C11H20N2O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(CC1)\C=N\O | 1g | 268500283
1-PIPERIDINECARBOXYLIC ACID,4-[(HYDROXYIMINO)METHYL]-,1,1-DIMETHYLETHYL ESTER | AstaTech | 190446-85-6 | MFCD11616948 | 228.292 | C11H20N2O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(CC1)\C=N\O | 1g | 268500283
eMolecules 301180-04-1 | N-Cbz-3-piperidinecarboxylic acid t-butyl ester | Combi-Blocks | MFCD04038570 | 319.401 | C18H25NO4 | 98.000 | CC(C)(C)OC(=O)C1CCCN(C1)C(=O)OCc1ccccc1 | 1g | 537622785
N-Cbz-3-piperidinecarboxylic acid t-butyl ester | Combi-Blocks | 301180-04-1 | MFCD04038570 | 319.401 | C18H25NO4 | 98.000 | CC(C)(C)OC(=O)C1CCCN(C1)C(=O)OCc1ccccc1 | 1g | 537622785
Medchemexpress LLC Alectinib | 1256580-46-7 | MFCD19440988 | 5mg
Alectinib | Purity: 99.87% | MW: 482.62 | 1256580-46-7 | MFCD19440988 | 5mg
Medchemexpress LLC Gemigliptin tartrate | 1374639-74-3 | 99.5% | 639.45 | 50 MG
Gemigliptin tartrate is a highly selective, reversible, and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor with an IC50 of 10.3 nM for human recombinant DPP-4. It exhibits potent anti-glycation properties and can be utilized for research into advanced glycation end products (AGE)-related diabetic complications.
- Highly selective, reversible, and competitive DPP-4 inhibitor
- Exhibits potent anti-glycation properties
- Can be used for research into advanced glycation end products (AGE)-related diabetic complications
- Inhibits the formation of AGE-BSA
- Suppresses the cross-linking of preformed AGE-BSA
- Dose-dependently inhibits plasma DPP-4 activity in rats, dogs, and monkeys
- Significantly reduces circulating AGE levels in serum in vivo
eMolecules 1799711-29-7 | Thalidomide-O-amido-C3-PEG3-C1-NH2 | ChemScene648.589 | C27H35F3N4O11 | 97.000 | OC(=O)C(F)(F)F.NCCCOCCOCCOCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12 | 25mg | 572198149
Thalidomide-O-amido-C3-PEG3-C1-NH2 | ChemScene | 1799711-29-7648.589 | C27H35F3N4O11 | 97.000 | OC(=O)C(F)(F)F.NCCCOCCOCCOCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12 | 25mg | 572198149
Medchemexpress LLC FGI-106 tetrahydrochloride | 1149348-10-6 | 99.7% | 604.49 g·mol⁻¹ | C28H42Cl4N6 | 10MG
FGI-106 tetrahydrochloride is the tetrahydrochloride salt of FGI-106, a broad-spectrum antiviral small molecule reported to inhibit viruses such as Ebola, Rift Valley fever, and dengue in vitro. It is supplied as a solid tetrahydrochloride salt for research use.
- Chemical name: FGI-106 tetrahydrochloride (CAS 1149348-10-6).
- Molecular formula: C28H42Cl4N6; molecular weight: 604.49 g·mol⁻¹.
- Purity: 99.7% (as supplied).
- Physical form: light brown to brown solid (tetrahydrochloride salt).
- Storage: store solid at 4°C, sealed, away from moisture; in solution, -80°C up to 6 months or -20°C up to 1 month.
- Packaging: available in multiple milligram-scale packages for research use.
Medchemexpress LLC Rhodamine-N3 chloride | 2363751-90-8 | 99.9% | 847.44 | 5 MG
Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye utilized for labeling biomolecules that contain alkyne groups. It functions as a click chemistry reagent, possessing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups, exhibiting an excitation/emission (Ex/Em) profile of 544/576 nm.
- Azide-rhodamine fluorescent dye
- Click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
- Excitation/emission (Ex/Em) = 544/576 nm
- Enables labeling of biomolecules with alkyne groups
- Versatile for various click chemistry applications
Medchemexpress LLC ERRα ligand-linker conjugates 1 | 00-00-0 | 98.8% | C24H20F9N3O5 | 10MG
ERRα ligand-linker conjugate combines an ERRα-targeting ligand with a PROTAC-compatible linker to serve as a building block for synthesis of ERRα-directed degraders and related conjugates. Supplied as a solid with documented purity, molecular properties, and recommended storage for research applications.
- Designed for use in PROTAC synthesis and conjugation.
- High purity: 98.8%.
- Molecular weight: 601.42 g·mol⁻¹.
- Molecular formula: C24H20F9N3O5.
- Soluble in DMSO up to 200 mg/mL; ultrasonic may be needed.
- Appearance: light yellow to yellow solid.
- Recommended storage: store under nitrogen at -20°C; in solution keep at -80°C for long-term.
Selleck Chemical LLC BSJ-4-116-5mg
BSJ-4-116 is a specific degrader of cyclin-dependent kinase 12 (CDK12). BSJ-4-116 exhibits potent antiproliferative effects.
Medchemexpress LLC BSJ-4-116 | 2519823-34-6 | 99.9% | 837.38 | 50 MG
BSJ-4-116 is a PROTAC (proteolysis-targeting chimera) designed to selectively degrade CDK12 (Cyclin-Dependent Kinase 12) with high potency, evidenced by an IC50 of 6 nM. It achieves its effect by linking ligands for Cereblon and CDK, leading to the downregulation of DNA damage response (DDR) genes through premature transcriptional termination and increased poly(adenylation). This compound exhibits significant antiproliferative capabilities, both as a standalone agent and in combination with the PARP inhibitor Olaparib. It has been shown to decrease CDK12 protein levels regardless of the cell line's mutational status and can overcome resistance due to specific CDK12 mutations.
- Highly potent and selective CDK12 degrader
- Downregulates DNA damage response genes
- Exhibits antiproliferative effects
- Can overcome resistance from specific CDK12 mutations
Medchemexpress LLC HY-103632 10mg Medchemexpress, PROTAC BRD9 Degrader-1 CAS:2097971-01-0 Purity:>98%
Medchemexpress, HY-103632 10mg PROTAC BRD9 Degrader-1 CAS:2097971-01-0 PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader (IC50=13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Pomalidomide-C12-NH2 hydrochloride | 2862774-02-3 | 97.1% | C25H37ClN4O4 | 50 MG
Pomalidomide-C12-NH2 hydrochloride is an E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1. This is a Cereblon-based KRASG12C degrader.
- E3 ligase ligand-linker conjugate
- Cereblon-based degrader
- Intended for research use only
eMolecules 1617495-03-0 | Medchem Express | RA190 | 5mg | 446255996 | HY-100739 | 596.75 | C28H23Cl5N2O2
ChemScene | Methyl 1-(3-amino-4-(4-methylpiperazin-1-yl)phenyl)-1H-123-triazole-4-carboxylate | 100mg | 726025536 | CS-0542335 | 2250024-95-2 | 316.365 | C15H20N6O2
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Medchemexpress LLC Pomalidomide-C12-NH2 hydrochloride | 2862774-02-3 | 97.1% | 493.04 g/mol | C25H37ClN4O4 | 5 MG
Pomalidomide-C12-NH2 hydrochloride is an E3 ligase ligand-linker conjugate used as the Cereblon-directed ligand component in PROTAC design targeting KRAS G12C. Supplied as the hydrochloride salt for research use, it is provided as a solid in milligram scales and is characterized by high purity and defined storage recommendations.