Piperidines
TARGETMOL CHEMICALS INC Levobupivacaine 50MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes.Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Adverse drug reactions (ADRs) are rare when it is administered correctly. Purity 99.7%
Medchemexpress LLC Nelfinavir | 159989-64-7 | C32H45N3O4S | 1 MG
Nelfinavir is a potent, orally bioavailable HIV-1 protease inhibitor, showing strong efficacy against HIV infection with a Ki of 2 nM. This compound also functions as a broad-spectrum anticancer agent.
- Potent and orally bioavailable HIV-1 protease inhibitor
- Broad-spectrum anticancer agent
- Inhibits proliferation of multiple myeloma cells
- Inhibits 26S chymotrypsin-like proteasome activity
- Triggers apoptosis in myeloma cell lines and fresh plasma cells
- Decreases phosphorylation of AKT, STAT-3, ERK1/2
- Activates pro-apoptotic pathway of the unfolded protein response system
- Decreases multiple myeloma cell growth in NOD/SCID mice
Selleck Chemical LLC Nelfinavir Mesylate S4282-10mM/1mL
Nelfinavir Mesylate is a potent HIV protease inhibitor with Ki of 2 nM
Medchemexpress LLC Sulfuric acid, mono [(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester | 1192500-31-4 | 99.3% | 265.24 | 1 ML
Avibactam free acid, also known as NXL-104 free acid, is a potent covalent and reversible non-β-lactam β-lactamase inhibitor. It demonstrates strong inhibitory activity against β-lactamase TEM-1 and CTX-M-15, with IC50 values of 8 nM and 5 nM, respectively. This compound exhibits minimal antibacterial activity on its own but is effective in inhibiting Class A and C β-lactamases. It does not inhibit metallo β-lactamases or Acinetobacter OXA carbapenemases.
- Broad-spectrum β-lactamase inhibition
- Synergistic activity
- In vivo efficacy
- Research applications
Medchemexpress LLC Mepivacaine hydrochloride | 1722-62-9 | 99.7% | 1 ML
Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, inhibiting both sodium influx and membrane depolarization. This blockage of nerve impulse initiation and conduction results in a reversible loss of sensation. It has a more rapid onset and moderate duration of action compared to other local anesthetics. It also displays a preferential use-dependent block of Na(v)1.8.
- Inhibits sodium influx and membrane depolarization
- Results in reversible loss of sensation
- Rapid onset of action
- Moderate duration of action
- Displays preferential use-dependent block of Na(v)1.8
Medchemexpress LLC (+)-Mepivacaine | 24358-84-7 | 99.7% | 10 MG
(+)-Mepivacaine is the (+) enantiomer of mepivacaine, an amide-type local anesthetic that blocks voltage-gated sodium channels to produce temporary loss of sensation. Supplied as a high-purity research chemical for pharmacological and electrophysiological studies.
- High purity (99.7%), suitable for research applications.
- Acts as a sodium channel blocker for studies of neuronal excitability.
- Available in small milligram quantities for laboratory use (5 mg, 10 mg, 25 mg).
- Molecular formula C15H22N2O; molecular weight 246.35.
- Offered as the (+) enantiomer for enantioselective research.
eMolecules 93138-55-7 | 3-(Piperidin-1-ylmethyl)aniline | Chem-Impex | MFCD04114502 | 190.290 | C12H18N2 | 95.000 | Nc1cccc(CN2CCCCC2)c1 | 1g | 386895570
3-(Piperidin-1-ylmethyl)aniline | Chem-Impex | 93138-55-7 | MFCD04114502 | 190.290 | C12H18N2 | 95.000 | Nc1cccc(CN2CCCCC2)c1 | 1g | 386895570
Medchemexpress LLC HY-10017 10mg Medchemexpress, SCH 546738 CAS:906805-42-3 Purity:>98%
Medchemexpress, HY-10017 10mg SCH 546738 CAS:906805-42-3 SCH 546738 is a potent, orally active and non-competitive CXCR3 antagonist, the affinity constant (Ki) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.4 nM in multiple experiments. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Piperine 94-62-2 5g
Piperine (CAS 94-62-2) is an alkaloid primarily found in black pepper (Piper nigrum) that has demonstrated diverse pharmacological activities It modulates several signaling pathways including inhibition of drug-metabolizing enzymes such as CYP3A4 and P-glycoprotein and affects cellular processes through regulation of MAPK and Akt phosphorylation Piperine has been studied for its potential to enhance the bioavailability of various therapeutic agents and for its anti-inflammatory anti-tumor and neuroprotective properties This compound is utilized in biomedical research to investigate drug-drug interactions signal transduction mechanisms and its impact on cellular proliferation and apoptosis
Apexbio Technology LLC Piperine 94-62-2 1g
Piperine (CAS 94-62-2) is an alkaloid primarily found in black pepper (Piper nigrum) that has demonstrated diverse pharmacological activities It modulates several signaling pathways including inhibition of drug-metabolizing enzymes such as CYP3A4 and P-glycoprotein and affects cellular processes through regulation of MAPK and Akt phosphorylation Piperine has been studied for its potential to enhance the bioavailability of various therapeutic agents and for its anti-inflammatory anti-tumor and neuroprotective properties This compound is utilized in biomedical research to investigate drug-drug interactions signal transduction mechanisms and its impact on cellular proliferation and apoptosis
Apexbio Technology LLC Piperine 94-62-2 10mM (in 1mL DMSO)
Piperine (CAS 94-62-2) is an alkaloid primarily found in black pepper (Piper nigrum) that has demonstrated diverse pharmacological activities It modulates several signaling pathways including inhibition of drug-metabolizing enzymes such as CYP3A4 and P-glycoprotein and affects cellular processes through regulation of MAPK and Akt phosphorylation Piperine has been studied for its potential to enhance the bioavailability of various therapeutic agents and for its anti-inflammatory anti-tumor and neuroprotective properties This compound is utilized in biomedical research to investigate drug-drug interactions signal transduction mechanisms and its impact on cellular proliferation and apoptosis
