Piperidines
eMolecules 1657014-42-0 | Medchem Express | GDC-0575 (dihydrochloride) | 5mg | 599150425 | HY-112167A | 451.19 | C16H22BrCl2N5O
Ambeed | 3-(Butane-1-sulfonyl)phenylboronic acid | 100mg | 731677120 | A821085 | 2377611-73-7 | MFCD27935662 | 242.100 | C10H15BO4S
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Medchemexpress LLC Tofacitinib metabolite-1 | 1640971-51-2 | MFCD32693921 | 99.6% | 328.37 g/mol | C16H20N6O2 | 5 MG
Tofacitinib metabolite-1 is a research-grade metabolite used for pharmacokinetic and metabolism studies of tofacitinib. It is supplied as a high-purity solid suitable for in vitro and in vivo formulation development, with documented solubility and storage conditions for preclinical use.
- Metabolite of tofacitinib for pharmacokinetic and metabolism studies.
- High purity (99.6%).
- Solid, light yellow to yellow appearance.
- Soluble in DMSO (100 mg/mL); in vivo formulations ≥2.5 mg/mL with appropriate co-solvents.
- Molecular formula C16H20N6O2; molecular weight 328.37 g/mol.
- Available in small research quantities (5 mg, 10 mg; larger sizes by quote).
- Store solid at 4°C protected from light; in solution store at -80°C for long-term stability.
Medchemexpress LLC DDO-2213 | 2378768-36-4 | C24H27ClFN7O | 50 MG
DDO-2213 | 2378768-36-4 | C24H27ClFN7O | 50 MG
STA Pharmaceutical 3-(N-Fmoc-amino)piperidine-3-carboxylic acid HCl | 50 g | CAS 368866-20-0 | MDL MFCD04113564
3-(N-Fmoc-amino)piperidine-3-carboxylic acid HCl is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 368866-20-0
- MDL: MFCD04113564
- InChIKey: GZXZDFOJUNNXPX-UHFFFAOYSA-N
- Molecular Weight: 402.875
- Molecular Formula: C21H23ClN2O4
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29333999
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)piperidine-3-carboxylic acid hydrochloride
- SMILES: O=C(OCC1C2=CC=CC=C2C3=C1C=CC=C3)NC4(CCCNC4)C(O)=O.Cl
Aobchem Methanone (3-fluoro-5-methylphenyl)(3-methylphenyl)- | 95% | CAS 1332354-78-5 | C15H13FO | 500mg
Methanone (3-fluoro-5-methylphenyl)(3-methylphenyl)- | 95% | CAS 1332354-78-5 | C15H13FO | 500mg
Medchemexpress LLC HY-B2215 50mg Medchemexpress, Dimemorfan (phosphate) CAS:36304-84-4 Purity:>98%
Medchemexpress, HY-B2215 50mg Dimemorfan (phosphate) CAS:36304-84-4 Dimemorfan phosphate is a sigma 1 receptor agonist, used as a potent antitussive. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10619D 5mg Medchemexpress, Niraparib R-enantiomer CAS:1038915-58-0 Purity:>98%
Medchemexpress, HY-10619D 5mg Niraparib R-enantiomer CAS:1038915-58-0 Niraparib R-enantiomer (MK-4827 R-enantiomer) is an excellent PARP1 inhibitor with IC50 of 2.4 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 3466-80-6 | Ambeed | 2-Phenylpiperidine | 1g | 491166965 | A118058 | MFCD00270125 | 161.248 | C11H15N
ChemScene | 4-(2-Bromophenyl)oxazole | 100mg | 712833151 | CS-0366275 | 850349-06-3 | MFCD08706070 | 224.057 | C9H6BrNO
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Medchemexpress LLC AMG-548 dihydrochloride | 2518299-32-4 | 99.9% | 534.48 | 50 MG
AMG-548 dihydrochloride is an orally active and selective inhibitor of p38α (Ki=0.5 nM), showing slight selectivity over p38β (Ki=36 nM) and more than 1000-fold selectivity against p38γ and p38δ. It is also highly potent in inhibiting whole blood LPS-stimulated TNFα (IC50=3 nM). Additionally, this compound inhibits Wnt signaling by directly targeting Casein kinase 1 isoforms δ and ε.
- Selective p38α inhibitor with high potency.
- Potent inhibition of whole blood LPS-stimulated TNFα and IL1β.
- Inhibits Wnt signaling through direct targeting of Casein kinase 1 isoforms δ and ε.
- Good oral bioavailability in vivo.
![Medchemexpress LLC 2-[(2-phenylethyl)thio]nicotinic acid | 496775-95-2 | MFCD03621206 | 99.8% | 259.32 g/mol | C14H13NO2S | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235232.png-250.jpg)
Medchemexpress LLC 2-[(2-phenylethyl)thio]nicotinic acid | 496775-95-2 | MFCD03621206 | 99.8% | 259.32 g/mol | C14H13NO2S | 50MG
ML-099 (CID-888706) is a small-molecule pan activator of Ras-related GTPases provided for research use. It enhances GTPase activity by increasing affinity for guanine nucleotides and activates multiple small GTPases relevant to cytoskeletal dynamics and signaling pathways. The compound is supplied as a solid in several pack sizes and as a DMSO solution for cell-based and biochemical assays.
![Medchemexpress LLC 6-[[4-(cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-indol-4-yl)-4-(4-morpholinyl)-thieno-pyrimidine | 955977-50-1 | 99.0% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230705.png-250.jpg)
Medchemexpress LLC 6-[[4-(cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-indol-4-yl)-4-(4-morpholinyl)-thieno-pyrimidine | 955977-50-1 | 99.0% | 50 MG
PI-3065 is a selective small-molecule inhibitor of PI3K p110δ used for research applications. It potently inhibits p110δ (IC50 5 nM; Ki 1.5 nM) and shows substantially lower activity against other PI3K isoforms, and is supplied as a solid for in vitro and in vivo studies.
- Potent p110δ inhibition (IC50 5 nM; Ki 1.5 nM).
- Reduced activity against p110α (IC50 910 nM), p110β (IC50 600 nM), p110γ (>10,000 nM).
- Purity approximately 98.97%.
- Chemical formula C27H31FN6OS; molecular weight 506.64 g/mol.
- Appearance: white to off-white solid.
- Soluble in DMSO (25 mg/mL) and formulatable for in vivo dosing.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years).
- Available in small-mass pack sizes (for example 50 mg).
eMolecules 3466-80-6 | 2-Phenylpiperidine | Ambeed | MFCD00270125 | 161.248 | C11H15N | 98.000 | C1CCC(NC1)c1ccccc1 | 5g | 552543121
2-Phenylpiperidine | Ambeed | 3466-80-6 | MFCD00270125 | 161.248 | C11H15N | 98.000 | C1CCC(NC1)c1ccccc1 | 5g | 552543121
Apexbio Technology LLC AT7867 857531-00-1 5mg
AT7867 (CAS 857531-00-1) is a small molecule ATP-competitive inhibitor that targets Akt1 Akt2 Akt3 p70S6 kinase (p70S6K) and protein kinase A (PKA) with reported IC50 values of 32 nM 17 nM 47 nM 85 nM and 20 nM respectively Akt or protein kinase B is a serine/threonine kinase involved in cellular pathways such as glucose metabolism apoptosis proliferation transcription and migration AT7867 suppresses proliferation across various human tumor cell lines including MES-SA MDA-MB-468 MCF-7 HCT116 and HT29 with IC50 values ranging from 0 9 to 3 M Additionally it inhibits GSK3 within these lines (IC50 2 4 M) and induces apoptosis in U87MG glioblastoma cells via dose- and time-dependent Akt pathway inhibition In PTEN-deficient tumor xenograft models AT7867 reduces phosphorylation of Akt/p70S6K substrates and impedes tumor growth supporting its use in cancer research
eMolecules 340-07-8 | 1-Trifluoroacetyl piperidine | Oakwood Chemical | MFCD00466213 | 181.158 | C7H10F3NO | 99.000 | FC(F)(F)C(=O)N1CCCCC1 | 25g | 537704748
1-Trifluoroacetyl piperidine | Oakwood Chemical | 340-07-8 | MFCD00466213 | 181.158 | C7H10F3NO | 99.000 | FC(F)(F)C(=O)N1CCCCC1 | 25g | 537704748