Piperidines
Enzo Life Sciences Arv-825 (5mg). CAS: 1818885-28-7
ARV-825 is a PROTAC targeting on BRD4, consisting of a BRD4-ligand JQ-1 linked to a cereblon E3 ligase ligand Pomalidomide, with Kds values of 90nM and 28nM for affinity to BD1 and BD2. Purity: ≥98%. Long Term Storage: -20°C.
Medchemexpress LLC HY-115446A 500mg Medchemexpress, Lenalidomide-C4-NH2 (hydrochloride) CAS: Purity:>98%
Medchemexpress, HY-19695 10mg (-)-p-Bromotetramisole (oxalate) CAS:62284-79-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0750B 200mg Medchemexpress, Dolasetron (Mesylate hydrate) CAS:878143-33-0 Purity:98%
Medchemexpress,HY-B0750B 200mg Dolasetron (Mesylate hydrate) CAS:878143-33-0 Formula:C20H26N2O7S Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 91531-30-5 | Medchem Express | Antineoplaston A10 | 5mg | 482204307 | HY-128553 | MFCD26961095 | 246.266 | C13H14N2O3
Medchem Express | Antineoplaston A10 | 5mg | 482204307 | HY-128553 | 91531-30-5 | MFCD26961095 | 246.266 | C13H14N2O3
Apexbio Technology LLC Lenalidomide hemihydrate 847871-99-2 50mg
Lenalidomide hemihydrate (CAS 847871-99-2) is a small-molecule immunomodulator targeting the E3 ubiquitin ligase CRBN It is designed to induce selective ubiquitination and degradation of the lymphoid transcription factors IKZF1 and IKZF3 thereby modulating immune cell signaling pathways Lenalidomide hemihydrate exerts its biological activity primarily by inhibiting TNF- secretion with an IC50 value of approximately 13 nM Its mechanism of action also includes altering cytokine production and cellular interactions within the tumor microenvironment Based on these pharmacological properties Lenalidomide hemihydrate holds research potential in the investigation of inflammatory pathways immune response modulation and antitumor mechanisms particularly in hematological malignancies and inflammatory diseases
Medchemexpress LLC Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride | 2245697-85-0 | 95.0% | 100 MG
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a thalidomide-derived cereblon ligand linked to a PEG4-C2 amine linker; supplied as the hydrochloride salt and intended as a building block for PROTAC and E3 ligase ligand-linker conjugates in research applications.
- Functions as an E3 ligase ligand-linker conjugate for PROTAC synthesis.
- Contains a thalidomide-derived cereblon ligand for target engagement.
- Includes a PEG4-based linker to provide flexibility and solubility.
- Supplied as a hydrochloride salt for improved handling.
- Typical purity ≥95% suitable for research use.
eMolecules 1799711-21-9 | Medchem Express | dBET1 | 5mg | 446257250 | HY-101838 | 785.27 | C38H37ClN8O7S
Ambeed | 4-Hydroxy-2-methylpyrimidine-5-carbonitrile | 250mg | 490493564 | A110380 | 27058-54-4 | MFCD17018685 | 135.126 | C6H5N3O
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Enzo Life Sciences Arv-825 (50mg). CAS: 1818885-28-7
ARV-825 is a PROTAC targeting on BRD4, consisting of a BRD4-ligand JQ-1 linked to a cereblon E3 ligase ligand Pomalidomide, with Kds values of 90nM and 28nM for affinity to BD1 and BD2. Purity: ≥98%. Long Term Storage: -20°C.
Medchemexpress LLC HY-A0003B 100mg Medchemexpress, Lenalidomide (hemihydrate) CAS:847871-99-2 Purity:>98%
Medchemexpress, HY-A0003B 100mg Lenalidomide (hemihydrate) CAS:847871-99-2 Lenalidomide hemihydrate (CC-5013 hemihydrate) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Apixaban-¹³C,d₃ | 1261393-15-0 | 99.5% | C2413CH22D3N5O4 | 5 MG
Apixaban-13C,d3 is a deuterium and 13C labeled Apixaban, a highly selective, reversible inhibitor of Factor Xa. It is suitable for use as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. This product is for research use only and not sold to patients. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development, and deuteration may affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes for quantitation in drug development
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs