Piperidines
Medchemexpress LLC CCT128930 hydrochloride | 2453324-32-6 | 99.0% | C18H21Cl2N5 | 10MG
CCT128930 hydrochloride is the hydrochloride salt of a selective ATP-competitive AKT inhibitor supplied as a powder for research use. It is employed in cellular assays to probe PI3K/Akt/mTOR signaling, induce cell cycle arrest, and study autophagy; handle and store according to the product SDS and COA.
Apexbio Technology LLC GBR 12935 dihydrochloride 67469-81-2 100mg
GBR 12935 dihydrochloride is a small-molecule inhibitor targeting the dopamine transporter (DAT) It is designed to inhibit DAT-mediated dopamine reuptake thereby modulating dopaminergic signaling and increasing extracellular dopamine levels GBR 12935 dihydrochloride exerts its biological activity primarily through direct blockade of neuronal dopamine uptake at the synaptic cleft Based on these pharmacological properties GBR 12935 dihydrochloride holds research potential in studies of dopaminergic signaling reward pathways addiction behaviors dopamine-related neurodegeneration and dopamine transporter function
![eMolecules AstaTech / ENCENICLINE / 0.1g / 721956328 / 43221 / 95.000 / 550999-75-2 / [null] / 357.290 / C16H18Cl2N2OS](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502468529.JPG-250.jpg)
eMolecules AstaTech / ENCENICLINE / 0.1g / 721956328 / 43221 / 95.000 / 550999-75-2 / [null] / 357.290 / C16H18Cl2N2OS
AstaTech / ENCENICLINE / 0.1g / 721956328 / 43221 / 95.000 / 550999-75-2 / [null] / 357.290 / C16H18Cl2N2OS
Apexbio Technology LLC SB 747651A dihydrochloride 10mg
SB 747651A dihydrochloride is a small-molecule inhibitor targeting mitogen- and stress-activated protein kinase 1 (MSK1) It is designed to selectively inhibit MSK1 activity thereby interfering with phosphorylation-mediated signal transduction pathways downstream of MSK1 SB 747651A dihydrochloride exerts its biological activity primarily through competitive inhibition of MSK1 kinase disrupting phosphorylation of the transcription factor CREB and histone H3 Based on these pharmacological properties SB 747651A dihydrochloride holds research potential in inflammation pathways stress-responsive gene regulation cellular proliferation and differentiation and neuronal plasticity
eMolecules (Fmoc-4-amino)piperidine hydrochloride | 221352-86-9 | 1G
Chem-Impex | (Fmoc-4-amino)piperidine hydrochloride | 1G | 221352-86-9 | MFCD12032216 | MW:351.4
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eMolecules 4-((4-Aminopiperidin-1-yl)methyl)benzonitrile hydrochloride | 1353977-72-6 | MFCD21098432 | 250mg
Ambeed | 4-((4-Aminopiperidin-1-yl)methyl)benzonitrile hydrochloride | 250mg | 525088186 | A171377 | | 1353977-72-6 | MFCD21098432 | 251.760 | C13H18ClN3
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STA PHARMACEUTICAL US LLC 3-(N-Fmoc-amino)piperidine-3-carboxylic acid HCl | 25 g | CAS 368866-20-0 | MDL MFCD04113564
3-(N-Fmoc-amino)piperidine-3-carboxylic acid HCl is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 368866-20-0
- MDL: MFCD04113564
- InChIKey: GZXZDFOJUNNXPX-UHFFFAOYSA-N
- Molecular Weight: 402.875
- Molecular Formula: C21H23ClN2O4
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29333999
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)piperidine-3-carboxylic acid hydrochloride
- SMILES: O=C(OCC1C2=CC=CC=C2C3=C1C=CC=C3)NC4(CCCNC4)C(O)=O.Cl
Medchemexpress LLC K-Ras-PDE -IN-1 25mg | 1841464-21-8 | 447.50 g/mol | C25H26FN5O2 | 25 MG
K-Ras-PDEδ-IN-1 is a small-molecule research compound that competitively inhibits PDEδ by binding the farnesyl-binding pocket with low nanomolar affinity (Kd ≈ 8 nM). It is supplied as a solid for in vitro and in vivo research applications and includes solubility and formulation guidance for biomedical studies.
- Potent competitive inhibitor of PDEδ with Kd ≈ 8 nM.
- Intended for use in Ras/PDEδ biological research in vitro and in vivo.
- Soluble in DMSO at about 12.5 mg/mL; in vivo suspension guidance at ~1.25 mg/mL with standard vehicle.
- Molecular formula C25H26FN5O2 and molecular weight 447.50 g/mol.
- Supplied as a solid powder suitable for biochemical and cellular assays.
Biotium Lambda Light ChainICO-106 CF594 conjugate 0.1mgmL
Lambda Light ChainICO-106 CF594 conjugate 0.1mgmL
Accela Chembio Inc N-boc-4-nortropinone | 5g | 185099-67-6 | MFCD00673779 | 98% | Shelf Life: 1980 Days | Regular
N-boc-4-nortropinone | 5g | 185099-67-6 | MFCD00673779 | 98% | Shelf Life: 1980 Days | Regular
Medchemexpress LLC Apixaban-13C,d3 (BMS-562247-01-13C,d3) | 1261393-15-0 | 99.5% | C2413CH22D3N5O4 | 1 MG
Apixaban-13C,d3 is a deuterium and 13C labeled version of Apixaban, also known as BMS-562247-01-13C,d3. Apixaban is recognized as a highly selective and reversible inhibitor of Factor Xa, demonstrating Ki values of 0.08 nM in humans and 0.17 nM in rabbits.
- Deuterium and 13C labeled compound.
- Highly selective, reversible inhibitor of Factor Xa.
- Can be used as a tracer in drug development processes.
- Suitable as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
Medchemexpress LLC HY-103636 10mg Medchemexpress, PROTAC Sirt2 Degrader-1 CAS:2098487-75-1 Purity:>98%
Medchemexpress, HY-103636 10mg PROTAC Sirt2 Degrader-1 CAS:2098487-75-1 PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s > 100 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC AS-99 TFA | 99.2% | C29H31F6N5O5S2 | 50 MG
AS-99 TFA is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor with anti-leukemic activity. It blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces leukemia burden in vivo. The compound exhibits over 100-fold selectivity towards ASH1L, showing no significant inhibition on a panel of 20 other histone methyltransferases at 50 μM.
- Potent and selective ASH1L histone methyltransferase inhibitor
- Blocks cell proliferation and induces apoptosis
- Downregulates MLL fusion target genes
- Reduces leukemia burden in vivo
- Exhibits over 100-fold selectivity towards ASH1L
- Favorable exposure in plasma with a half-life of approximately 5-6 hours