Pyrazines
TARGETMOL CHEMICALS INC GNF-5 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50 0.22±0.1 uM Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties. purity: 99%
TARGETMOL CHEMICALS INC NCGC00244536 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50 10 nM). purity: 99%
TARGETMOL CHEMICALS INC BYK204165 25MG
Also available in 1 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)purity: 99%
TARGETMOL CHEMICALS INC PLANTAGOSIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Plantagoside is a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50 5 uM). It also is a potent inhibitor of the Maillard reaction. purity: 99%
TARGETMOL CHEMICALS INC G36 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17(beta)-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM respectively). G36 has no detectable binding activity to either ER(alpha) or ER(beta). G36 blocks the activation of PI3K or calcium mobilization triggered by estrogen through GPER and it suppresses ERK activation by estrogen or G-1 but not by EGF. G-36 can be used in combination with GPER-selective agonists like G-1 to distinguish the roles of GPER from those of ER(alpha) and ER(beta) in complex biological systems. purity: 99%
TARGETMOL CHEMICALS INC ECABAPIDE 5MG
Also available in 1mg 10mg 25mg 50mg and bulk. Please contact Fisher for quotes. Ecabapide (DQ-2511) is a novel gastrointestinal motility promoter that significantly enhances gastric emptying in SHRSP.Ecabapide activates cyclic GMP-dependent housekeeping Cl- channels in rabbit gastric wall cells. purity: 99%
TARGETMOL CHEMICALS INC ASAPIPRANT 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Asapiprant (S-555739) is a potent and selective DP1 receptor antagonist (Ki 0.44 nM). It exhibited high affinity and selectivity for the DP1 receptor. purity: 99%
Accela Chembio Inc 2-aminopyrazine | 25g | 5049-61-6 | MFCD00006137 | 98% | Shelf Life: 1080 Days | Light Sensitive
2-aminopyrazine | 25g | 5049-61-6 | MFCD00006137 | 98% | Shelf Life: 1080 Days | Light Sensitive
TARGETMOL CHEMICALS INC GINKGOLIDE K 20MG
Also available in 5 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity. purity: 99%
TARGETMOL CHEMICALS INC LXH254 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LXH254 is a potent C-Raf and B-Raf inhibitor. purity: 99%
TARGETMOL CHEMICALS INC MPT0B014 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis. purity: 99%
TARGETMOL CHEMICALS INC ISPINESIB 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ispinesib (SB-715992) a selective effectvie and reversible inhibitor of kinesin spindle protein (KSP) is derived from quinazolinone with antineoplastic properties. purity: 99%
TARGETMOL CHEMICALS INC L82-G17 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI. purity: 99%
TARGETMOL CHEMICALS INC EN523 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EN523 targets non-catalytic allosteric cysteine C23 in K48 ubiquitin-specific deuquitinase OTUB1. purity: 98%