Pyrazines
TARGETMOL CHEMICALS INC HS-243 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity. purity: 97%
TARGETMOL CHEMICALS INC DPTIP 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM. purity: 98%
TARGETMOL CHEMICALS INC YO-01027 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. YO-01027 (DBZ) is a potent (gamma)-secretase inhibitor. purity: 99%
TARGETMOL CHEMICALS INC R-7050 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. R-7050 (TNF-(alpha) Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNF(alpha). purity: 99%
TARGETMOL CHEMICALS INC REPOTRECTINIB 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor with IC50 of 1.01 nM 5.3 nM 1.08 nM and 1.26 nM for WT ALK SRC ALK L1196M and ALK G1202R respectively. purity: 99%
TARGETMOL CHEMICALS INC GOLVATINIB 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2 which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of tumor cell types and play important roles in tumor cell growth migration and angiogenesis. purity: 98%
TARGETMOL CHEMICALS INC TALNIFLUMATE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. purity: 99%
TARGETMOL CHEMICALS INC DSS30 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. DSS30 is a P25/CDK5 inhibitor.DSS30 acts by inhibiting the phosphorylation of amyloid precursor protein cleaving enzyme 1 (BACEl) which reduces the secretion of (beta)-amyloid (A(beta)).DSS30 can be used for the prevention and treatment of neurodegenerative diseases such as Alzheimer's disease. purity: 99%
TARGETMOL CHEMICALS INC D75-4590 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. D75-4590 is a (beta)-16-Glucan inhibitor. As glucan is a major component of the cell wall specifically (beta)-16-Glucan D75-4590 can fight fungal infections by inhibiting its synthetase. purity: 99%
eMolecules 1250022-24-2 | 3-bromopyrazine-2-carbonitrile | MFCD16842970 | 1g
Medchem Express | Ibiglustat | 2mg | 446267809 | HY-16743 | 1401090-53-6 | MFCD28502073 | 389.490 | C20H24FN3O2S
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eMolecules Building Block Tool
Accela Chembio Inc 2-aminopyrazine | 100g | 5049-61-6 | MFCD00006137 | 98% | Shelf Life: 1080 Days | Light Sensitive
2-aminopyrazine | 100g | 5049-61-6 | MFCD00006137 | 98% | Shelf Life: 1080 Days | Light Sensitive
eMolecules 6905-47-1 | 2-Amino-6-methoxypyrazine | Combi-Blocks | MFCD09909689 | 125.131 | C5H7N3O | 98.000 | COc1cncc(N)n1 | 1g | 205413438
2-Amino-6-methoxypyrazine | Combi-Blocks | 6905-47-1 | MFCD09909689 | 125.131 | C5H7N3O | 98.000 | COc1cncc(N)n1 | 1g | 205413438
