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- (1)
- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Survodutide (TFA) | 2805997-46-8 | 99.9% | 4231.63 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Survodutide is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist. It is a 29-amino-acid peptide and a potent acylated peptide containing a C18 fatty acid, demonstrating robust anti-obesity efficacy by increasing energy expenditure and decreasing food intake.
- Potent, selective glucagon receptor/GLP-1 receptor dual agonist
- Demonstrates robust anti-obesity efficacy
- Increases energy expenditure and decreases food intake
- Enhanced proteolytic stability
- Extended terminal half-life
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC TXNL4B Human His 50ug | 50ug
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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TXNL4B Protein vital for pre-mRNA splicing is crucial for S/G(2) cell cycle transition forming homodimers and interacting with the U5-102 kDa spliceosome subunit It plays a key role in splicing intricacies and influences cell cycle dynamics TXNL4B Protein Human (His) is the recombinant human-derived TXNL4B protein expressed by E coli with N-His labeled tag
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Medchemexpress LLC IL-10 Virus 1mg | 1mg
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IL-10 Protein critically masks infected cells for immune evasion by down-regulating the host TAP1 gene hindering peptide transport into the endoplasmic reticulum and loading onto MHC class I molecules IL-10 also inhibits IFN-gamma synthesis and exists as a homodimer IL-10 Protein Virus is the recombinant Virus-derived IL-10 protein expressed by E coli with tag free
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Selleck Chemical LLC Anti-EFNA4-A2516-1MG-25
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Anti-EFNA4 (PF-06647263) is a antibody targeting EFNA4 MW 145 5 KD
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Medchemexpress LLC Autophagy inducer 7 | 944159-20-0 | 410.55 | 5 MG
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Autophagy inducer 7 (Compound SSA) is an Autophagy and Apoptosis inducer. It activates autophagy by inhibiting Akt/mTOR signaling and the expression of downstream proteins. It suppresses DNA synthesis and causes a G0-G1 cell-cycle arrest. Autophagy inducer 7 inhibits tumor cell growth.
- Inhibits the growth of human lung adenocarcinoma cell lines
- Induces apoptosis in various cell lines
- Inhibits DNA synthesis and increases cells in G0-G1 phase
- Induces autophagy and increases autophagic flux by inhibiting Akt/mTOR/p70S6k signaling
- Induces dose- and time-dependent cleavage of cytosolic LC3-I to autophagosome-associated LC3-II
- Decreased p62 expression
- Displayed accumulation of vesicle-like structures within the cytoplasm
- Increased both the number and size of acidic vesicles within the cytoplasm
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Medchemexpress LLC Ampiroxicam | 99464-64-9 | 98.7% | 447.46 | 5 MG
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Ampiroxicam | 99464-64-9 | 98.7% | 447.46 | 5 MG
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Medchemexpress LLC PKI-166 | 330.38 g/mol | C20H18N4O | 100MG
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PKI-166 is a potent selective and orally bioavailable EGFR tyrosine kinase inhibitor with an IC50 of 0 7 nM[1]
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Medchemexpress LLC 8-(6-Methoxypyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,5-dihydro-4H-triazolo | 2648986-65-4 | 99.9% | 521.49 | 50 MG
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CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM. It exhibits potent proliferation inhibition activity against multiple cancer cell lines. In vitro, CQ211 suppresses the phosphorylation of mTOR in cancer cells. It effectively inhibits the proliferation of MKN-1 and HT-29 cells, with IC50 values of 0.61 μM and 0.38 μM, respectively. In vivo, administration of CQ211 at 25 mg/kg was observed to inhibit the MKN-1 xenograft mouse model, resulting in a tumor growth inhibition (TGI) of 30.9%.
- Potent and selective RIOK2 inhibitor
- Exhibits proliferation inhibition activity against multiple cancer cell lines
- Suppresses phosphorylation of mTOR in cancer cells
- Inhibits MKN-1 and HT-29 cell proliferation
- Demonstrates tumor growth inhibition in xenograft mouse models
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Medchemexpress LLC c-Kit-IN-1 | 1225278-16-9 | MFCD09839958 | C26H21F2N5O3 | 50 MG
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c-Kit-IN-1 is a potent inhibitor of c-Kit and c-Met with IC50s of less than 200 nM. It also inhibits KDR, PDGFRα, and PDGFRβ. This product is a white to off-white solid with a purity of 98.26% and is designed for research use only.
- Potent inhibitor of c-Kit and c-Met
- Inhibits KDR, PDGFRα, and PDGFRβ
- High purity (98.26%)
- Supplied as a white to off-white solid
- Powder stable at -20°C for 3 years or 4°C for 2 years
- In solvent stable at -80°C for 2 years or -20°C for 1 year
- Soluble in DMSO at 100 mg/mL
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Medchemexpress LLC Benzo[b]thiophene-2-carboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- | 474432-65-0 | 99.90% | 423.57 | 25 MG
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FAUC 346 is a highly selective D3 partial agonist with an EC50 of 1.5 nM. It is intended for research use only.
- Highly selective D3 partial agonist with an EC50 of 1.5 nM
- D3-selective ligand with a Ki of 0.23 nM in CHO cells for the D3 receptor
- Shows affinity for 5HT1A receptors (Ki = 41 nM) and α1 receptors (Ki = 15 nM)
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Medchemexpress LLC Ibrolipim (NO-1886) | 133208-93-2 | 99.5% | 451.25 g/mol | C19H20BrN2O4P | 1 ML
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Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL)-promoting small molecule used in research on lipid metabolism and cardiovascular disease. It is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and is also available as solid quantities for custom preparation. Reported molecular weight is 451.25 g/mol and CAS is 133208-93-2.
- Ready-to-use 10 mM solution in DMSO, 1 mL
- High reported purity (~99.5%)
- Suitable for in vitro and in vivo lipid metabolism studies
- Also available as solids for custom solution preparation
- Characterized compound with CAS 133208-93-2 and known molecular weight
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Medchemexpress LLC Cytokeratin 18 Antib | 50UL
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Cytokeratin 18 Antib | 50UL
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eMolecules 286-22-6 | 3,7-dioxabicyclo[4.1.0]heptane | Pharmablock | MFCD11226853 | 100.117 | C5H8O2 | 97.000 | C1CC2OC2CO1 | 50g | 551212311
3,7-dioxabicyclo[4.1.0]heptane | Pharmablock | 286-22-6 | MFCD11226853 | 100.117 | C5H8O2 | 97.000 | C1CC2OC2CO1 | 50g | 551212311
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Medchemexpress LLC 1383727-17-0 | 50MG
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1383727-17-0 | 50MG
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Cambridge Isotope Laboratories Glycan-F61 (unlabeled) 500 pmol
Glycan-F61 (unlabeled) 500 pmol
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