Pyridines and derivatives
Chloropyramine hydrochloride
CAS: 6170-42-9 Molecular Formula: C16H21Cl2N3 Molecular Weight (g/mol): 326.27 MDL Number: MFCD00079009 InChI Key: VEYWWAGBHABATA-UHFFFAOYSA-N Synonym: chloropyramine hydrochloride,chloropyramine hcl,alergosan,nilfan,allergan s hydrochloride,chlorpiramin hydrochloride,halopyramine hydrochloride,chlorpyramin hcl,chlorpyramine hydrochloride,unii-fwa92z14nn PubChem CID: 80311 IUPAC Name: hydrogen N-[(4-chlorophenyl)methyl]-N-[2-(dimethylamino)ethyl]pyridin-2-amine chloride SMILES: [H+].[Cl-].CN(C)CCN(CC1=CC=C(Cl)C=C1)C1=CC=CC=N1
2-Amino-3-hydroxypyridine 98.0+%, TCI America™
CAS: 16867-03-1 Molecular Formula: C5H6N2O Molecular Weight (g/mol): 110.116 MDL Number: MFCD00006317 InChI Key: BMTSZVZQNMNPCT-UHFFFAOYSA-N Synonym: 2-amino-3-hydroxypyridine,2-amino-3-pyridinol,3-pyridinol, 2-amino,2-amino-3-pyridol,3-hydroxy-2-pyridinamine,2-amino-pyridin-3-ol,2-amino-3-hydroxy pyridine,unii-p8740pew4b,3-hydroxy-2-aminopyridine,pubchem2574 PubChem CID: 28114 IUPAC Name: 2-aminopyridin-3-ol SMILES: C1=CC(=C(N=C1)N)O
2-Amino-3-bromo-5-chloropyridine 98.0+%, TCI America™
CAS: 26163-03-1 Molecular Formula: C5H4BrClN2 Molecular Weight (g/mol): 207.455 MDL Number: MFCD00955627 InChI Key: UWGGGYYCKDCTGN-UHFFFAOYSA-N Synonym: 2-amino-3-bromo-5-chloropyridine,3-bromo-5-chloro-2-pyridinamine,2-pyridinamine, 3-bromo-5-chloro,3-bromo-5-chloro-2-pyridylamine,3-bromo-5-chloropyrid-2-ylamine,3-bromo-5-chloro-pyridin-2-ylamine,abbypharma ap-10-5406,3-bromo-5-chloro-pyridin-2-amine,pubchem1141,acmc-1ch3b PubChem CID: 2763971 IUPAC Name: 3-bromo-5-chloropyridin-2-amine SMILES: C1=C(C=NC(=C1Br)N)Cl
4-Bromo-2-pyridinecarboxylic Acid 98.0+%, TCI America™
CAS: 30766-03-1 Molecular Formula: C6H4BrNO2 Molecular Weight (g/mol): 202.007 MDL Number: MFCD03426665 InChI Key: RPHHYRNGCJYQSP-UHFFFAOYSA-N Synonym: 4-bromopicolinic acid,4-bromo-2-pyridinecarboxylic acid,4-bromo-pyridinecarboxylic acid,2-pyridinecarboxylic acid, 4-bromo,4-bromo-pyridine-2-carboxylic acid,aurora 23242,pubchem4064,acmc-209hio,ksc222g5r PubChem CID: 735150 IUPAC Name: 4-bromopyridine-2-carboxylic acid SMILES: C1=CN=C(C=C1Br)C(=O)O
4,4'-Dimethyl-2,2'-bipyridyl 1-Oxide 98.0+%, TCI America™
CAS: 81998-03-0 Molecular Formula: C12H12N2O Molecular Weight (g/mol): 200.241 MDL Number: MFCD11042487 InChI Key: VNSKKRAUVGCMPH-UHFFFAOYSA-N PubChem CID: 13586792 IUPAC Name: 4-methyl-2-(4-methylpyridin-2-yl)-1-oxidopyridin-1-ium SMILES: CC1=CC(=NC=C1)C2=[N+](C=CC(=C2)C)[O-]
3,5-Dimethyl-4-nitro-2-pyridinemethanol 98.0+%, TCI America™
CAS: 149082-03-1 Molecular Formula: C8H10N2O3 Molecular Weight (g/mol): 182.179 MDL Number: MFCD03426035 InChI Key: KBCDOXSSYLFMHH-UHFFFAOYSA-N Synonym: 3,5-dimethyl-4-nitropyridin-2-yl methanol,3,5-dimethyl-2-hydroxymethyl-4-nitropyridine,3,5-dimethyl-4-nitropyridine-2-methanol,3,5-dimethyl-4-nitro-2-pyridinemethanol,2-hydroxymethyl-3,5-dimethyl-4-nitropyridine,3,5-dimethyl-4-nitro-2-pyridyl-1-methanol,2-pyridinemethanol, 3,5-dimethyl-4-nitro,3,5-dimethyl-4-nitro-2-pyridyl methan-1-ol,4-nitro-3,5-dimethyl-2-hydroxymethyl pyridine PubChem CID: 4049415 IUPAC Name: (3,5-dimethyl-4-nitropyridin-2-yl)methanol SMILES: CC1=CN=C(C(=C1[N+](=O)[O-])C)CO
Harmol 98.0+%, TCI America™
CAS: 487-03-6 Molecular Formula: C12H10N2O Molecular Weight (g/mol): 198.225 MDL Number: MFCD00834164 InChI Key: LBBJNGFCXDOYMQ-UHFFFAOYSA-N Synonym: 7-Hydroxy-1-methyl-9H-pyrido[3,4-b]indole, 1-Methyl-9H-pyrido[3,4-b]indol-7-ol PubChem CID: 68094 IUPAC Name: 1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one SMILES: CC1=C2C(=C3C=CC(=O)C=C3N2)C=CN1
Apexbio Technology LLC Toltrazuril 69004-03-1 5g
Toltrazuril (69004-03-1) is an antiprotozoal compound targeting coccidial parasites It is designed to interfere with mitochondrial energy metabolism and the division of protozoan parasites thereby inhibiting parasite proliferation Toltrazuril exerts its biological activity primarily through disruption of mitochondrial function in protozoa In in vitro studies toltrazuril demonstrates inhibitory activity against coccidial parasites with reported IC50 values typically ranging from 0 02 to 0 3 g/mL depending on testing conditions and parasite species Based on these pharmacological properties toltrazuril holds research potential in experimental investigations of antiprotozoal mechanisms parasite-host interactions and therapeutic evaluations against protozoan pathogens
Medchemexpress LLC Obacunone | 751-03-1 | 454.51 | 1 ML
Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. It exerts its anticancer effects by inducing apoptosis and protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage. This product is an analytical standard intended for research and analytical applications.
- Inhibits UVR-induced cytotoxicity
- Improves UVR-induced oxidative damage in ARPE-19 cells
- Slows UVR-induced apoptosis in human ARPE-19 cells and murine RPE cells
- Inhibits bleomycin-induced lung inflammation and fibrosis
- Activates the Nrf2-dependent antioxidant responses
Medchemexpress LLC Toltrazuril | 69004-03-1 | 99.5% | 1 G
Toltrazuril is an antiprotozoal agent specifically targeting Coccidia parasites. It operates by inducing structural changes in coccidian developmental stages, affecting the endoplasmic reticulum, Golgi apparatus, and peri-nuclear space, leading to disturbed nuclear division.
- Acts upon Coccidia parasites
- Induces structural changes in coccidian developmental stages
- Affects endoplasmic reticulum and Golgi apparatus
- Causes abnormalities in the peri-nuclear space
- Disturbs nuclear division
- Demonstrates high efficacy in fecal oocyst count reduction
Medchemexpress LLC Toltrazuril | 69004-03-1 | 99.5% | 1 ML
Toltrazuril (BAY-i 9142) is a potent antiprotozoal agent specifically targeting Coccidia parasites. It operates by inducing significant changes in the fine structure of coccidian development stages, causing swelling of the endoplasmic reticulum and Golgi apparatus, alongside abnormalities in the peri-nuclear space and disruptions in nuclear division. This mechanism leads to a substantial reduction in oocyst counts, demonstrating high efficacy against coccidial infections.
- Acts as an effective antiprotozoal agent against Coccidia parasites.
- Induces structural changes in coccidian development stages.
- Significantly reduces oocyst counts in treated subjects.
- Demonstrates high and sustained efficacy over treatment periods.
Apexbio Technology LLC TAI-1 1334921-03-7 100mg
TAI-1 (CAS 1334921-03-7) is a small molecule inhibitor targeting the protein Hec1 It functions by disrupting the interaction between Hec1 and Nek2 prompting Nek2 degradation chromosome misalignment at metaphase and apoptotic cell death Demonstrating a GI50 of 13 48 nM in K562 cells TAI-1 exhibits significantly increased inhibitory potency compared to earlier Hec1 inhibitors such as INH1 TAI-1 displays antiproliferative activity across diverse tumor cell types particularly in cell lines lacking functional P53 or RB genes It also enhances chemotherapeutic efficacy when combined with agents like topotecan paclitaxel and doxorubicin TAI-1 is orally active in in vivo models supporting its utility as a practical tool in oncology research
Apexbio Technology LLC TAI-1 1334921-03-7 25mg
TAI-1 (CAS 1334921-03-7) is a small molecule inhibitor targeting the protein Hec1 It functions by disrupting the interaction between Hec1 and Nek2 prompting Nek2 degradation chromosome misalignment at metaphase and apoptotic cell death Demonstrating a GI50 of 13 48 nM in K562 cells TAI-1 exhibits significantly increased inhibitory potency compared to earlier Hec1 inhibitors such as INH1 TAI-1 displays antiproliferative activity across diverse tumor cell types particularly in cell lines lacking functional P53 or RB genes It also enhances chemotherapeutic efficacy when combined with agents like topotecan paclitaxel and doxorubicin TAI-1 is orally active in in vivo models supporting its utility as a practical tool in oncology research
Medchemexpress LLC Obacunone | 751-03-1 | 454.51 | 100 MG
Obacunone (Standard) is the analytical standard for Obacunone, designed for research and analytical applications. It is a highly oxidized triterpenoid limonoid, naturally isolated from various citrus plants. Obacunone demonstrates anticancer properties primarily by inducing apoptosis and offers protective effects against ultraviolet (UV) radiation-induced oxidative damage in retinal pigment epithelial (RPE) cells.
- Used as a reference standard in qualitative, quantitative, and methodological research experiments.
- Commonly employed in techniques such as HPLC, GC, and MS.