Pyridines and derivatives
2,4-Dibromopyridine 98.0+%, TCI America™
CAS: 58530-53-3 Molecular Formula: C5H3Br2N Molecular Weight (g/mol): 236.89 MDL Number: MFCD01859720 InChI Key: PCMMSLVJMKQWMQ-UHFFFAOYSA-N Synonym: 2,4-dibromo-pyridine,pyridine, 2,4-dibromo,2,4-dibrompyridin,pubchem5452,acmc-1av5w,2,4-dibromopyridine,ksc493e4t PubChem CID: 817104 IUPAC Name: 2,4-dibromopyridine SMILES: BrC1=CC=NC(Br)=C1
2-(4-Fluorophenyl)pyridine 98.0+%, TCI America™
CAS: 58861-53-3 Molecular Formula: C11H8FN Molecular Weight (g/mol): 173.19 MDL Number: MFCD06201382 InChI Key: MHWIDTQQBWGUCD-UHFFFAOYSA-N PubChem CID: 100868 IUPAC Name: 2-(4-fluorophenyl)pyridine SMILES: C1=CC=NC(=C1)C2=CC=C(C=C2)F
2-Bromo-3-nitropyridine 98.0+%, TCI America™
CAS: 19755-53-4 Molecular Formula: C5H3BrN2O2 Molecular Weight (g/mol): 203.00 MDL Number: MFCD00955613 InChI Key: ZCCUFLITCDHRMG-UHFFFAOYSA-N Synonym: 2-bromo-3-nitro-pyridine,pyridine, 2-bromo-3-nitro,pyridine, 2-bromonitro,pubchem5955,acmc-1bt4y,2-bromo-3-nitro pyridine,#,ksc490s2t,2-bromo-3-nitropyridine PubChem CID: 555054 IUPAC Name: 2-bromo-3-nitropyridine SMILES: [O-][N+](=O)C1=CC=CN=C1Br
2,3-Diamino-5-bromopyridine 98.0+%, TCI America™
CAS: 38875-53-5 Molecular Formula: C5H7BrN3 Molecular Weight (g/mol): 189.04 MDL Number: MFCD00460094 InChI Key: YRGMYJUKFJPNPD-UHFFFAOYSA-O Synonym: 2,3-diamino-5-bromopyridine,5-bromo-2,3-diaminopyridine,5-bromo-2,3-pyridinediamine,2,3-pyridinediamine, 5-bromo,3-amino-5-bromopyridin-2-yl amine,abbypharma ap-17-5972,5-brompyridin-2,3-diamin,pubchem5383,acmc-1adjl,5-brompyridin-2,3-diamine PubChem CID: 691156 IUPAC Name: 2,3-diamino-5-bromopyridin-1-ium SMILES: NC1=CC(Br)=C[NH+]=C1N
5-Amino-3-bromo-2-chloropyridine 95.0+%, TCI America™
CAS: 130284-53-6 Molecular Formula: C5H4BrClN2 Molecular Weight (g/mol): 207.46 MDL Number: MFCD03840433 InChI Key: ISKBXMMELYRESC-UHFFFAOYSA-N PubChem CID: 14595221 IUPAC Name: 5-bromo-6-chloropyridin-3-amine SMILES: NC1=CC(Br)=C(Cl)N=C1
4,6-Dichloro-2-methylquinoline 98.0+%, TCI America™
CAS: 53342-53-3 Molecular Formula: C10H7Cl2N Molecular Weight (g/mol): 212.073 MDL Number: MFCD00272372 InChI Key: KYBCQZHRJZJYCE-UHFFFAOYSA-N Synonym: 4,6-Dichloroquinaldine PubChem CID: 12322577 IUPAC Name: 4,6-dichloro-2-methylquinoline SMILES: CC1=NC2=C(C=C(C=C2)Cl)C(=C1)Cl
Apexbio Technology LLC Isocytosine 108-53-2 100mg
Isocytosine (CAS 108-53-2) is a non-canonical nucleobase and a structural isomer of cytosine It serves as an analog in nucleic acid research notably as a component of expanded genetic systems such as hachimoji RNA and can pair with isoguanine to model non-standard base pairing Mechanistically isocytosine has been shown to modulate specific signaling pathways and enzyme activities in experimental systems It is widely utilized in molecular biology and genetics to investigate alternative base-pairing nucleic acid stability and the physicochemical properties of synthetic genetic polymers
Apexbio Technology LLC Cedrol 77-53-2 100mg
Cedrol (CAS 77-53-2) is a small-molecule inhibitor targeting cytochrome P450 (CYP) enzymes It is designed to competitively inhibit CYP-mediated metabolic activity thereby modulating xenobiotic metabolism and related cellular processes Cedrol exerts its biological activity primarily through competitive binding to CYP enzymes In enzyme inhibition assays Cedrol demonstrates inhibitory effects with an IC50 value ranging from 15 50 M depending on CYP isoform and experimental conditions Based on these pharmacological properties Cedrol holds research potential in anti-cancer strategies management of oxidative stress and inflammatory responses neuropathic pain models antibacterial applications anxiety reduction and the prevention of hair loss
Medchemexpress LLC Rosmanol | 80225-53-2 | 50 MG
Rosmanol can inhibit the oxidation of low-density lipoprotein (LPL) and significantly inhibit lipopolysaccharide-induced iNOS and COX-2 expression, demonstrating an anti-inflammatory effect.
- Inhibits oxidation of low-density lipoprotein (LPL)
- Significantly inhibits lipopolysaccharide-induced iNOS expression
- Significantly inhibits lipopolysaccharide-induced COX-2 expression
- Demonstrates anti-inflammatory effects
Medchemexpress LLC D-Arabinopyranose | 28697-53-2 | 500 MG
D-Arabinopyranose is an analytical standard intended for research and analytical applications as a laboratory chemical. This monosaccharide shows strong growth inhibition against *Caenorhabditis elegans* with an IC50 of 7.5 mM.
- Used as a reference standard in qualitative, quantitative, and methodological research
- Suitable for experiments in HPLC, GC, and MS
- Appears as a white to off-white solid
- Initial source is microorganisms
- For research use only
- Melting/freezing point: 162-164 °C
- Relative density: 1.1897 g/cm³
Medchemexpress LLC Isocytosine | 108-53-2 | 111.10 | 5 G
Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and as a nucleobase of hachimoji RNA.
- Non-natural nucleobase and an isomer of cytosine.
- Used in studies of unnatural nucleic acid analogues of normal base pairs in DNA.
- Used as a nucleobase of hachimoji RNA.
Medchemexpress LLC LX2343 | 333745-53-2 | 99.8% | 5 G
LX2343 is a BACE1 enzyme inhibitor that also acts as a non-ATP competitive PI3K inhibitor. It stimulates autophagy to promote Aβ clearance.
- BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM.
- Non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM.
- Stimulates autophagy.
- Promotes Aβ clearance.
Medchemexpress LLC LX2343 | 333745-53-2 | 474.91 | 100 MG
LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. It acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance, ameliorating cognitive dysfunction in APP/PS1 transgenic mice via both Aβ production inhibition and clearance promotion, which highlights its potential in the treatment of AD.
- Dose-dependently decreased Aβ accumulation in HEK293-APPsw and CHO-APP cells.
- Promotes Aβ clearance in SH-SY5Y cells and primary astrocytes.
- Antagonizes prolonged path lengths and escape latencies in the MWM test in APP/PS1 mice.
Medchemexpress LLC Rosmanol | 80225-53-2 | MFCD00010834 | 25 MG
Rosmanol | 80225-53-2 | MFCD00010834 | 25 MG