Pyridines and derivatives
2,6-Dimethyl-3-nitropyridine 98.0+%, TCI America™
CAS: 15513-52-7 Molecular Formula: C7H8N2O2 Molecular Weight (g/mol): 152.153 MDL Number: MFCD00023503 InChI Key: AETHUDGJSSKZKT-UHFFFAOYSA-N PubChem CID: 84958 IUPAC Name: 2,6-dimethyl-3-nitropyridine SMILES: CC1=NC(=C(C=C1)[N+](=O)[O-])C
Apexbio Technology LLC Azelnidipine 123524-52-7 10mg
Azelnidipine (CAS 123524-52-7) is a dihydropyridine-based small molecule that functions as an L-type calcium channel blocker By inhibiting calcium influx through these channels azelnidipine effectively modulates vascular smooth muscle tone resulting in vasodilation and reduced blood pressure In preclinical studies acute administration of azelnidipine has been shown to prevent abrupt declines in cardiac function following acute stress events This compound is utilized in biomedical research to investigate the cellular and systemic mechanisms underlying calcium channel modulation and the physiological response to antihypertensive therapies
Apexbio Technology LLC CITCO 338404-52-7 10mg
CITCO (CAS 338404-52-7) is an imidazothiazole derivative that selectively activates the human constitutive androstane receptor (CAR) exhibiting an EC50 of 49 nM and over 50-fold selectivity for CAR compared to the pregnane X receptor (PXR) with negligible activity on other nuclear receptors Activation of CAR by CITCO facilitates its nuclear translocation and subsequent binding to response elements regulating gene expression processes involved in hepatic detoxification pathways Additionally CITCO-mediated CAR activation has been shown to suppress the proliferation and expansion of brain tumor stem cells supporting its utility in studies of xenobiotic metabolism and cancer biology
Apexbio Technology LLC CITCO 338404-52-7 5mg
CITCO (CAS 338404-52-7) is an imidazothiazole derivative that selectively activates the human constitutive androstane receptor (CAR) exhibiting an EC50 of 49 nM and over 50-fold selectivity for CAR compared to the pregnane X receptor (PXR) with negligible activity on other nuclear receptors Activation of CAR by CITCO facilitates its nuclear translocation and subsequent binding to response elements regulating gene expression processes involved in hepatic detoxification pathways Additionally CITCO-mediated CAR activation has been shown to suppress the proliferation and expansion of brain tumor stem cells supporting its utility in studies of xenobiotic metabolism and cancer biology
Apexbio Technology LLC CITCO 338404-52-7 25mg
CITCO (CAS 338404-52-7) is an imidazothiazole derivative that selectively activates the human constitutive androstane receptor (CAR) exhibiting an EC50 of 49 nM and over 50-fold selectivity for CAR compared to the pregnane X receptor (PXR) with negligible activity on other nuclear receptors Activation of CAR by CITCO facilitates its nuclear translocation and subsequent binding to response elements regulating gene expression processes involved in hepatic detoxification pathways Additionally CITCO-mediated CAR activation has been shown to suppress the proliferation and expansion of brain tumor stem cells supporting its utility in studies of xenobiotic metabolism and cancer biology
Medchemexpress LLC Pellitorine | 18836-52-7 | 1 MG
Pellitorine is a bioactive natural amide compound that competitively antagonizes TRPV1 activation, thereby reducing pain signal transmission. It improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways, and exerts anti-inflammatory and anti-sepsis effects. Additionally, Pellitorine exhibits antithrombotic activity, inhibits lipid peroxidation, resists ferroptosis, and shows anti-cancer properties. It also acts as an insecticide against Aedes aegypti mosquito larvae.
- Reduces pain by antagonizing TRPV1 activation.
- Improves cognitive function via BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways.
- Exerts anti-inflammatory and anti-sepsis effects.
- Provides antithrombotic effects.
- Inhibits lipid peroxidation and resists ferroptosis.
- Kills Aedes aegypti mosquito larvae.
- Exhibits anti-cancer activity (leukemia and breast cancer).
- Inhibits growth of certain bacteria.
Medchemexpress LLC Vorasidenib 25mg | 1644545-52-7 | 25MG
Vorasidenib (AG-881) is an orally available brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG) and the IC50 ranges of 0 04 22 nM against IDH1 R132C IDH1 R132G IDH1 R132H and IDH1 R132S and 7 14 nM against IDH2 R140Q and 130 nM against IDH2 R172K Vorasidenib can be used for the study of grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1/2 mutation[1 [2
Medchemexpress LLC Mudanpioside J | 262350-52-7 | 5 MG
Mudanpioside J is a chemical compound with the molecular formula C31H34O14 and a molecular weight of 630.6 g/mol.
- Identified by PubChem CID 21593828
- Identified by CAS number 262350-52-7
Medchemexpress LLC Mudanpioside J | 262350-52-7 | 1 MG
Mudanpioside J is a monoterpene glycoside, identified as a metabolite of cortex moutan. It possesses a molecular formula of C31H34O14 and a molecular weight of 630.59. This compound is typically provided for research purposes only.
- Monoterpene glycoside compound
- Metabolite of cortex moutan
- Molecular formula: C31H34O14
- Molecular weight: 630.59
- High purity: 95.0%
- For research use only
Medchemexpress LLC Seocalcitol | 134404-52-7 | 99.3% | 10 MG
Seocalcitol is a synthetic vitamin D analog provided as a white to off-white solid for research use. It binds the vitamin D receptor with high affinity and is used to study VDR-mediated signaling, antiproliferative effects, and calcium-related pathways in cellular and tissue assays. For research use only; not for human or veterinary use.
- High purity (99.3%).
- White to off-white solid form.
- Supplied as 10 MG quantity.
- Molecular formula C30H46O3; molecular weight 454.68 g/mol.
- Binds vitamin D receptor with Kd of 0.27 nM (MG-63 cells).
- Protect from light and store under nitrogen; recommend 4°C storage; in solvent: -80°C for up to 6 months or -20°C for up to 1 month.
Medchemexpress LLC Ceftobiprole | 209467-52-7 | 534.57 | 1 MG
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin-resistant (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC90 value of 2 μg/mL for MRSA. It also inhibits gram-positive and gram-negative pathogens, and can be used for the study of hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia.
- Broad-spectrum cephalosporin
- High levels of in vitro activity against methicillin-resistant (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci
- Inhibits gram-positive and gram-negative pathogens
- Can be used for the study of hospital-acquired pneumonia and community-acquired pneumonia
Medchemexpress LLC MTSSL | 81213-52-7 | 95.07% | 25 MG
MTSSL (Otmpmms) is a highly reactive thiol-specific spin label. It is utilized for labeling protein thiol residues to determine protein structure and dynamics, and for studies involving protein-protein interactions.
- Highly reactive thiol-specific spin label
- Labels protein thiol residues for structure and dynamics determination
- Used in protein-protein interaction studies
- Solid appearance
- Off-white to light yellow color
- Molecular weight: 264.38
- Chemical formula: C10H18NO3S2
- Purity: 95.07%
- Recommended storage temperature: 4°C, stored under nitrogen
- In solvent: -80°C for 6 months; -20°C for 1 month (stored under nitrogen)
Medchemexpress LLC Seocalcitol | 134404-52-7 | 99.3% | 454.68 | 5 MG
Seocalcitol | 134404-52-7 | 99.3% | 454.68 | 5 MG