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Filtered Search Results
Medchemexpress LLC MTOR INHIBITOR-8 50 mg
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MTOR INHIBITOR-8 50MG
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eMolecules 75894-93-8 | 2-(3,5-Dibromophenyl)ethanol | Oakwood Chemical | MFCD11617976 | 279.959 | C8H8Br2O | 95.000 | OCCc1cc(Br)cc(Br)c1 | 1g | 537711235
2-(3,5-Dibromophenyl)ethanol | Oakwood Chemical | 75894-93-8 | MFCD11617976 | 279.959 | C8H8Br2O | 95.000 | OCCc1cc(Br)cc(Br)c1 | 1g | 537711235
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Medchemexpress LLC PKI(5-24) | 99534-03-9 | 99.99% | 2222.38 | 10 MG
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PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. It corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor. This 20-residue peptide inhibits phosphotransferase activity of the mutant cGMP kinase with higher potency (Ki of 42 μM) than that of the wild type (Ki of 160 μM). This product is for research use only.
- Potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase)
- Ki of 2.3 nM
- Corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor
- 20-residue peptide synthesized to correspond to the active site of the skeletal muscle inhibitor protein
- Inhibits phosphotransferase activity of the mutant cGMP kinase with higher potency
- For research use only
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Medchemexpress LLC HY-10115A 100mg , PI-103 (Hydrochloride) CAS:371935-79-4 Purity:98%
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Medchemexpress, HY-10115A 100mg PI-103 (Hydrochloride) CAS:371935-79-4 Formula:C19H17ClN4O3 IC50: 8 nM (p110α), 88 nM (p110β), 48 nM (p110δ), 150 nM (p110γ), 2 nM (DNA-PK), 20 nM (mTORC1), 83 nM (mTORC2), 26 nM (PI3KC2β), 850 nM (ATR), 920 nM (ATM), ~1 μM (PI3KC2α), 2.3 μM (hsVPS34), ~50 μM (PI4KIIIβ) Purity:98% PI-103 Hydrochloride is a potent PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α , p110β , p110δ , p110γ , mTORC1 , and mTORC2 . PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Derenofylline | 251945-92-3 | 99.9% | 308.38 | 50 MG
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Derenofylline (SLV 320) is a potent, selective, and orally active adenosine A1 receptor antagonist. It exhibits Ki values of 1 nM for human A1, 200 nM for A3, and 398 nM for A2A receptors. This compound suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats. It has also shown to inhibit TGF-β1-induced myofibroblast transformation in vitro and reduce myocardial fibrosis in vivo.
- Potent, selective, and orally active adenosine A1 receptor antagonist
- Suppresses cardiac fibrosis
- Attenuates albuminuria
- Inhibits TGF-β1-induced myofibroblast transformation (in vitro)
- Reduces myocardial fibrosis in 5/6 nephrectomy rats (in vivo)
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Medchemexpress LLC TBK1 IKK -IN-5 10 mg
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TBK1 IKK -IN-5 10MG
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Medchemexpress LLC 4-PYRIMIDIN-5-YLBE 250 mg
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4-PYRIMIDIN-5-YLBE 250MG
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Medchemexpress LLC SSD114 hydrochloride | 2319790-02-6 | MFCD31619246 | 99.1% | 387.83 | C18H21ClF3N3O | 25 MG
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SSD114 hydrochloride is a small-molecule positive allosteric modulator of the GABAB receptor intended for in vitro and in vivo research use only.
- Acts as a GABAB receptor positive allosteric modulator for pharmacological studies.
- High purity suitable for research applications.
- Solid, white to off-white appearance for ease of handling.
- Available in multiple small-scale quantities for experimental flexibility.
- Stable under recommended storage conditions to preserve compound integrity.
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Medchemexpress LLC PKI-166 10mg | 187724-61-4 | 330.38 | C20H18N4O | 10 MG
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PKI-166 is a potent, selective, and orally bioavailable epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with a reported IC50 of 0.7 nM. It is provided for research use only and has molecular formula C20H18N4O and high purity by HPLC.
- Potent EGFR kinase inhibition (IC50 ≈ 0.7 nM).
- High chemical purity (≥98% by HPLC).
- Suitable for in vitro and in vivo research applications.
- Orally bioavailable in preclinical studies.
- Well-characterized molecular properties for experimental reproducibility.
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Medchemexpress LLC 5-PYRIMIDIN-5-YLIS 100 mg
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5-PYRIMIDIN-5-YLIS 100MG
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Apexbio Technology LLC TELOTRISTAT 5MG
TELOTRISTAT 5MG APEXBIO TECHNOLOGIES
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Medchemexpress LLC 4-pyrimidinemethanol | 33581-98-5 | MFCD03789625 | ≥97.0% | 110.11 | C5H6N2O | 500 MG
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Pyrimidin-4-yl-methanol (4-pyrimidinemethanol) is a small-molecule synthetic intermediate used in medicinal and pharmaceutical chemistry for constructing pyrimidine-containing compounds. It is supplied as a solid (light yellow to yellow), with molecular formula C5H6N2O, molecular weight 110.11, CAS 33581-98-5, and typical purity ≥97%. Available in multiple pack sizes for research and synthesis.
- Useful intermediate for synthesis of pyrimidine derivatives.
- High reported purity suitable for research and development.
- Well-defined molecular formula and molecular weight for formulation and analysis.
- Supplied as a solid for straightforward handling and storage.
- Available in multiple pack sizes to support different scales of work.
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eMolecules 854890-84-9 | 1-(2,5-Dibromophenyl)thiourea | Combi-Blocks | MFCD14673413 | 310.010 | C7H6Br2N2S | 98.000 | NC(=S)Nc1cc(Br)ccc1Br | 1g | 117531798
1-(2,5-Dibromophenyl)thiourea | Combi-Blocks | 854890-84-9 | MFCD14673413 | 310.010 | C7H6Br2N2S | 98.000 | NC(=S)Nc1cc(Br)ccc1Br | 1g | 117531798
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Medchemexpress LLC MG-2119 | 1065500-40-4 | 99.7% | C27H29N5O4 | 10MG
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MG-2119 is a small-molecule inhibitor that blocks monomeric tau and alpha-synuclein aggregation. It is supplied as a high-purity research compound intended for preclinical studies probing neurodegenerative disease mechanisms and aggregation-targeted screening. The compound is compatible with common biochemical and cell-based assay workflows when prepared according to standard laboratory protocols.
- High purity suitable for research assays.
- Inhibits tau and alpha-synuclein aggregation in vitro.
- Available in multiple small-scale pack sizes for screening.
- Soluble in DMSO for solution preparation.
- Provides structural data (SMILES) and molecular weight for cheminformatics.
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Aobchem 5-(4-Fluorophenyl)pyrimidin-2-amine | ≥97% | CAS 31408-40-9 | C10H8FN3 | 500mg
5-(4-Fluorophenyl)pyrimidin-2-amine | ≥97% | CAS 31408-40-9 | C10H8FN3 | 500mg
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