Pyrimidines And Derivatives
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Filtered Search Results
Aobchem AOBCHEM
5000939682 ETHYL PERFLUOROPHENYL SULFANE
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Medchemexpress LLC Darizmetinib | 2369583-33-3 | C21H17F2N5O3S | 250 MG
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Darizmetinib is an orally active, potent, and selective inhibitor of mitogen-activated protein kinase kinase 4 (MKK4; MAP2K4). It selectively targets, binds to, and inhibits the activity of MKK4 in liver cells. This inhibition enhances MKK7 and JNK1 signaling pathways, activating transcription factors ATF2 and ELK1, which promotes cell proliferation and liver regeneration. Darizmetinib is promising for research to prevent liver failure after extensive oncological liver resections or transplantation of small liver grafts.
- Orally active, potent, and selective MKK4 inhibitor
- Enhances MKK7 and JNK1 signaling pathways
- Activates transcription factors ATF2 and ELK1
- Promotes hepatocyte proliferation and survival
- Aids liver regeneration following hepatectomy
- Potential to prevent liver failure and restore liver mass
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Medchemexpress LLC Methyl orsellinate | 3187-58-4 | 5 G
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Methyl orsellinate is a phytotoxic compound that exhibits antifungal activities. It functions as a 5-lipoxygenase inhibitor with an IC50 value of 59.6 μM and is utilized in fungal infection research.
- Exhibits antifungal activities
- Functions as a 5-lipoxygenase inhibitor with an IC50 value of 59.6 μM
- Utilized in fungal infection research
- Phytotoxic compound
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Medchemexpress LLC Methyl orsellinate | 3187-58-4 | MFCD00184668 | 250 MG
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Methyl orsellinate is a phytotoxic compound with antifungal activities. It acts as a 5-lipoxygenase inhibitor with an IC50 value of 59.6 μM and can be utilized for fungal infection research.
- Phytotoxic compound
- Antifungal activities
- 5-lipoxygenase inhibitor
- Used for fungal infection research
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Medchemexpress LLC 5'-Guanylic acid | 85-32-5 | 25MG
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5'-Guanylic acid is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. It also regulates the expression of genes related to fatty acid metabolism.
- Weak agonist for ionotropic glutamate receptors (iGluR).
- Reduces the activity of the glutamatergic system.
- Exhibits neuroprotective effect.
- Can also cause neuronal cell death at high concentrations.
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Medchemexpress LLC 5- 4-ISOPROPYLPIPERA 250 mg
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5- 4-ISOPROPYLPIPERA 250MG
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eMolecules 171096-32-5 | methyl 2-(4,6-dihydroxypyrimidin-5-yl)acetate | MFCD20526413 | 1g
Medchem Express | C16-Ceramide | 5mg | 784543531 | HY-100354 | 24696-26-2 | MFCD00871748 | 537.914 | C34H67NO3
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eMolecules Building Block Tool
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Accela Chembio Inc 4 | 6-dihydroxy-5-nitropyrimidine | 100g | 2164-83-2 | MFCD00006110 | 97+% | Shelf Life: 2520 Days | Light Sensitive
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4 | 6-dihydroxy-5-nitropyrimidine | 100g | 2164-83-2 | MFCD00006110 | 97+% | Shelf Life: 2520 Days | Light Sensitive
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Selleck Chemical LLC Guanine S4888-25mg
Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA
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Accela Chembio Inc 5-amino-4 | 6-dihydroxypyrimidine | 1g | 69340-97-2 | MFCD00239457 | 95+% | Shelf Life: 1800 Days | Light Sensitive
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5-amino-4 | 6-dihydroxypyrimidine | 1g | 69340-97-2 | MFCD00239457 | 95+% | Shelf Life: 1800 Days | Light Sensitive
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Accela Chembio Inc 4 | 6-dihydroxy-2-methylpyrimidine | 25g | 40497-30-1 | MFCD00006104 | 97+% | Shelf Life: 1620 Days | Regular
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4 | 6-dihydroxy-2-methylpyrimidine | 25g | 40497-30-1 | MFCD00006104 | 97+% | Shelf Life: 1620 Days | Regular
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Apexbio Technology LLC Guanine 73-40-5 5g
Guanine (CAS 73-40-5) is a purine nucleobase characterized by a fused pyrimidine and imidazole ring system with conjugated double bonds As an integral component of DNA and RNA guanine forms hydrogen bonds with cytosine to facilitate nucleic acid base pairing thus playing a central role in the storage and transmission of genetic information It is frequently utilized in research investigating nucleic acid structure replication mutagenesis and enzymatic processes involving nucleotide metabolism or signaling pathways
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Aobchem AOBCHEM
5001081590 N- 4-METHOXYPHENYL PYRIMIDIN-2
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Aobchem AOBCHEM
5001082423 2- O-TOLYLOXY PYRIMIDIN-5-YL
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Aobchem 4-(Pyrimidin-2-yloxy)phenylboronic acid pinacol ester | ≥95% | CAS 330792-87-5 | C16H19BN2O3 | 5g
4-(Pyrimidin-2-yloxy)phenylboronic acid pinacol ester | ≥95% | CAS 330792-87-5 | C16H19BN2O3 | 5g
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