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Filtered Search Results
Medchemexpress LLC Auristatin E | 160800-57-7 | MFCD25976744 | 99.9% | 732.01 g/mol | C40H69N5O7 | 250 MG
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Auristatin E is a synthetic cytotoxic peptide that inhibits microtubule polymerization and is used as a payload in antibody-drug conjugate research. It is an analogue of dolastatin 10 and blocks cell division by preventing tubulin polymerization.
- High purity suitable for research applications.
- Inhibits tubulin polymerization to block cell division.
- Used as a cytotoxic payload in antibody-drug conjugate research.
- Contains CAS number 160800-57-7 and molecular weight 732.01 g/mol.
- Available in laboratory pack sizes, including a 250 mg option.
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Medchemexpress LLC 9-METHYL-B-CARBOLINE 10MM/1ML
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9-METHYL-B-CARBOLINE 10MM/1ML
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Medchemexpress LLC Codlemone (codlelure) | 33956-49-9 | 95.2% | 182.30 g/mol | C12H22O | 250MG
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Codlemone (codlelure) is the primary sex pheromone of the codling moth and is supplied as a purified natural-product analytical standard and lure for entomology research, monitoring, and integrated pest management studies. It is appropriate for analytical reference, behavioral assays, and field trapping applications.
- Primary sex pheromone for codling moth monitoring.
- Suitable as an analytical standard for GC/MS and behavioral assays.
- Approx. 95.2% purity.
- Molecular formula C12H22O; molecular weight 182.30 g/mol.
- Packaged as 250 mg and intended for refrigerated long-term storage.
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Medchemexpress LLC PYRIMIDINE-4 6-DICAR 25G
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PYRIMIDINE-4 6-DICAR 25G
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Medchemexpress LLC Afatinib impurity 4 | 74874-10-5 | MFCD08458426 | 250mg
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Afatinib impurity 4 is an impurity of Afatinib (HY-10261)
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Medchemexpress LLC BIX-01294 | 935693-62-2 | 98.4% | 490.64 | 250 MG
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BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of 1.7 μM and 0.9 μM, respectively. It inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. This (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative induces necroptosis and autophagy and has antitumor activity in recurrent tumor cells.
- Reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor
- Induces necroptosis and autophagy
- Exhibits antitumor activity in recurrent tumor cells
- Inhibits G9a/GLP by competing for binding with amino acids N-terminal of substrate lysine residue
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MEDCHEMEXPRESS LLC PICTILISIB DIMETHANESULFONATE
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501873810 PICTILISIB DIMETHANESULFONATE
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Medchemexpress LLC Isoxadifen-ethyl | 163520-33-0 | ≥97.0% | 1 ML
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Isoxadifen-ethyl is a widely used herbicide safener in rice that can decrease the phytotoxicity caused by fenoxaprop-P-ethyl. It is for research use only.
- Functions as a widely used herbicide safener.
- Decreases phytotoxicity caused by fenoxaprop-P-ethyl.
- Intended for research use only.
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Medchemexpress LLC PK11007 | 874146-69-7 | 98.7% | 100 MG
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PK11007 is a mild thiol alkylator exhibiting anticancer activity. It stabilizes p53 by selectively alkylating two surface-exposed cysteines without altering its DNA binding activity. This compound induces mutant p53 cancer cell death by elevating reactive oxygen species (ROS) levels. It is intended for research use only.
- Causes viability reduction in mutant p53 cell lines.
- Up-regulates protein levels of p53 target genes.
- Increases p53 activity.
- Increases reactive oxygen species (ROS) levels.
- Inhibits cell proliferation and induces apoptosis.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000744732 SULFOXFLUOR 250MG
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Apexbio Technology LLC Rofecoxib 162011-90-7 250mg
Rofecoxib (CAS 162011-90-7) is a selective inhibitor of cyclooxygenase-2 (COX-2) designed to provide anti-inflammatory effects with improved gastrointestinal tolerance compared to non-selective NSAIDs It demonstrates potent inhibition of COX-2 in cell-based assays with IC50 values ranging from 18 to 46 nM In osteosarcoma cells Rofecoxib suppresses prostaglandin E2 (PGE2) synthesis (IC50 26 nM) and inhibits recombinant human COX-2 in stably transfected CHO cells (IC50 18 nM) In biochemical assays using purified human COX-2 the IC50 is 0 34 M In vivo Rofecoxib reduces carrageenan-induced edema and hyperalgesia in rats (ID50 1 1 5 mg/kg) It is widely used in studies investigating COX-2-mediated inflammatory pathways and analgesia
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000770807 IRPPY2BPYPF6 250MG
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Medchemexpress LLC METHYL 10-BROMODECAN 250 mg
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METHYL 10-BROMODECAN 250MG
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eMolecules 1367970-52-2 | 1-(2-(Trifluoromethyl)pyrimidin-5-yl)ethanone | Ambeed | MFCD22062627 | 190.125 | C7H5F3N2O | 97.000 | CC(=O)c1cnc(nc1)C(F)(F)F | 250mg | 600847496
1-(2-(Trifluoromethyl)pyrimidin-5-yl)ethanone | Ambeed | 1367970-52-2 | MFCD22062627 | 190.125 | C7H5F3N2O | 97.000 | CC(=O)c1cnc(nc1)C(F)(F)F | 250mg | 600847496
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eMolecules Ethyl cyclopropanecarboxylate | Combi-Blocks, Inc.MFCD00001282 | 114.144 | C6H10O2 | 98.000 | CCOC(=O)C1CC1 | 5g | 603146508
Ethyl cyclopropanecarboxylate | Combi-Blocks, Inc.MFCD00001282 | 114.144 | C6H10O2 | 98.000 | CCOC(=O)C1CC1 | 5g | 603146508
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