Pyrroles
Medchemexpress LLC Hlcl-61 hydrochloride | 1158279-20-9 | 99.9% | 380.91 | C23H25ClN2O | 5 MG
HLCL-61 hydrochloride is a first-in-class small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) used for research to probe PRMT5-mediated methylation and cellular responses. It reduces cell growth in a dose-dependent manner across multiple leukemia cell lines and inhibits symmetric arginine dimethylation of histones H3 and H4, supporting studies of epigenetic regulation and oncology research.
- Targets PRMT5 to inhibit arginine methylation.
- Reduces cell proliferation in leukemia cell lines; IC50s reported by manufacturer.
- High purity suitable for research applications.
- Soluble in DMSO (50 mg/mL); insoluble in water.
- Solid, white to off-white appearance; store sealed away from moisture under recommended conditions.
eMolecules 958002-33-0 | Medchem Express | Beclabuvir | 1mg | 446261241 | HY-12429 | 659.85 | C36H45N5O5S
Medchem Express | Beclabuvir | 1mg | 446261241 | HY-12429 | 958002-33-0 | 659.850 | C36H45N5O5S
Enzo Life Sciences ET B receptor antagonist. sodium salt (0.5mg). CAS: 156161-89-6
Highly potent and selective ETB-receptor antagonist. Alternative name: BQ-788 . Na. Formula: C34H50N5O7Na. MW: 663.7. Purity: ≥95% (HPLC). Appearance: White to off-white powder. Formulation: Lyophilized from 0.1M sodium bicarbonate. Peptide content: 75-95%. Solubility: Soluble in methanol (0.5mg/ml), DMSO (4mg/ml), 0.1M sodium bicarbonate (3mg/ml) or 100% ethanol (4mg/ml); insoluble in water. Long Term Storage: -20°C.
eMolecules 851376-05-1 | Medchem Express | JNJ-18038683 | 5mg | 506404111 | HY-19889 | 529.97 | C26H28ClN3O7
Medchem Express | JNJ-18038683 | 5mg | 506404111 | HY-19889 | 851376-05-1 | 529.970 | C26H28ClN3O7
Medchemexpress LLC Tlr7/8/9-in-1 | 2180127-82-4 | 98.5% | 435.60 g/mol | C27H37N3O2 | 5 MG
TLR7/8/9-IN-1 is a potent, orally bioavailable small-molecule antagonist of Toll-like receptors 7, 8, and 9 used in preclinical studies to inhibit TLR signaling and downstream cytokine release. The compound is supplied as a high-purity solid with published in vitro and in vivo solubility and activity data.
- Potent antagonist activity (IC50 = 43 nM in TLR7/8/9 assays)
- Demonstrates 4.8 nM potency versus TLR7 in PBMC IL-6 reduction
- High reported purity of 98.5%
- Molecular weight 435.60 g/mol; formula C27H37N3O2
- Solid, off-white to light-yellow physical appearance
- Soluble in DMSO (83.33 mg/mL) and formulated for in vivo use (≥2.08 mg/mL)
- Suitable for preclinical studies of TLR pathway modulation
Medchemexpress LLC HY-109020 5mg Medchemexpress, Acrizanib CAS:1229453-99-9 Purity:>98%
Medchemexpress, HY-109020 5mg Acrizanib CAS:1229453-99-9 Acrizanib is a VEGFR-2 inhibitor, with an IC 50 of 17.4 nM for BaF3-KDR. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Acemetacin 53164-05-9 1g
Acemetacin (CAS 53164-05-9) is a non-steroidal anti-inflammatory compound structurally classified as a glycolic acid ester derivative of indometacin It exerts its pharmacological effects by inhibiting cyclooxygenase (COX) enzymes thereby suppressing prostaglandin synthesis involved in inflammation and pain signaling pathways Acemetacin is commonly employed in biomedical research to investigate COX-mediated processes and the modulation of inflammatory responses as well as to explore pathways related to non-steroidal anti-inflammatory drug (NSAID) pharmacodynamics and safety profiles
Medchemexpress LLC HY-15440B 5mg Medchemexpress, Fostemsavir Tris CAS:864953-39-9 Purity:>98%
Medchemexpress, HY-15440B 5mg Fostemsavir Tris CAS:864953-39-9 Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 2-Acetylpyrrole | 1072-83-9 | 99.5% | 109.13 | 100 G
2-Acetylpyrrole is an organic compound containing a pyrrole ring. It is a product of the Maillard browning reaction and serves as a major flavor component in many foods. It can also function as an intermediate in the synthesis of other active compounds, such as the flavor compound 2-acetyl-1-pyrroline. In vitro, 2-Acetylpyrrole reacts with nitrite to form 1-nitro-2-acetylpyrrole (NAP) and 1,3,5-trinitro-2-acetylpyrrole (TNAP), which demonstrate moderate mutagenicity and strong cytotoxicity.
- Organic compound with a pyrrole ring
- Product of Maillard browning reaction
- Major flavor component in many foods
- Intermediate in the synthesis of active compounds
eMolecules 1415390-47-4 | Medchem Express | (R)-BPO-27 | 1mg | 446270328 | HY-19778 | MFCD30532675 | 548.349 | C26H18BrN3O6
Ambeed | 5-Nitroquinoxaline | 250mg | 525227737 | A599476 | 18514-76-6 | MFCD01684951 | 175.147 | C8H5N3O2
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