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Filtered Search Results
Medchemexpress LLC 3,6,9,16-Tetraoxaheptadecanoic acid, 17-phenyl-, 1,1-dimethylethyl ester | 2381196-81-0 | 95.8% | 100 MG
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Boc-C1-PEG3-C4-OBn is a PROTAC linker, which refers to the PEG composition. It can be used in the synthesis of various PROTACs. PROTACs consist of two distinct ligands linked by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTAC linker with PEG composition
- Can be used in the synthesis of various PROTACs
- Targets an E3 ubiquitin ligase and a protein of interest
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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Medchemexpress LLC Azido-PEG9-Boc | 1818294-43-7 | C25H49N3O11 | 50 MG
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Azido-PEG9-Boc is a PEG-based PROTAC linker that is used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, making it versatile for various chemical reactions.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN group-containing molecules.
- Facilitates the synthesis of PROTACs, which utilize the intracellular ubiquitin-proteasome system to degrade target proteins.
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Medchemexpress LLC Boc-NH-PEG6-amine | 1G
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Boc-NH-PEG6-amine | 1G
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Medchemexpress LLC Azido-PEG3-C-Boc | 250MG
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Azido-PEG3-C-Boc | 250MG
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Medchemexpress LLC {Boc}-Met-Leu-Phe | 67247-12-5 | MFCD00037435 | 99.9% | 509.66 g/mol | C25H39N3O6S | 5 MG
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Boc-MLF (Boc-Met-Leu-Phe-OH) is a Boc-protected tripeptide that acts as a formyl peptide receptor (FPR) antagonist. It reduces fMLF-induced superoxide production with a reported IC50 of 0.63 μM and is supplied as a purified powder for research use. The compound is readily soluble in DMSO and can be formulated for in vivo dosing using common co-solvents.
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Medchemexpress LLC HS-PEG6-CH2CH2-Boc | 1818294-40-4 | >98.0% | C19H38O8S | 10MG
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HS-PEG6-CH2CH2-Boc is a polyethylene glycol (PEG)-based PROTAC linker featuring a protected thiol and a tert-butyloxycarbonyl (Boc)-protected terminus. It is supplied at high purity (>98%), has molecular formula C19H38O8S and molecular weight 426.57 g·mol⁻¹, and is soluble in DMSO (10 mM), making it suitable for use in small-molecule linker assembly.
- Provides a flexible, hydrophilic spacer for connecting ligands in PROTAC synthesis.
- Contains a protected thiol for selective deprotection and conjugation.
- Features a Boc-protected terminus compatible with standard amine deprotection chemistry.
- High reported purity supports reliable synthetic outcomes.
- Soluble in DMSO at 10 mM for convenient handling in solution-phase reactions.
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Medchemexpress LLC Z-Leu-Leu-Nle-CHO | 133407-83-7 | 97.6% | 25 MG
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Z-LLNle-CHO (Z-Leu-Leu-Nle-CHO) is a peptidic aldehyde γ-secretase inhibitor used in biochemical research to study protease activity, apoptosis, and signal transduction. Supplied as a solid for laboratory use, it is commonly used in enzyme inhibition and cell-based assays.
- Peptidic aldehyde inhibitor of γ-secretase and related proteases.
- Molecular formula C26H41N3O5 and molecular weight 475.62 g·mol⁻¹.
- Available in small milligram quantities suitable for research use.
- Certificate of analysis and RP-HPLC data available.
- Used in biochemical assays, apoptosis studies, and protease inhibition experiments.
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Medchemexpress LLC (E/Z)-MitoTam iodide, hydriodide | 98.6% | 999.82 g·mol⁻¹ | C52H60I2NOP | 5 MG
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(E/Z)-MitoTam iodide, hydriodide is the E/Z isomeric mixture of a tamoxifen-derived mitochondrial electron transport chain inhibitor used in research to disrupt mitochondrial respiration, alter mitochondrial morphology, and induce apoptosis in cancer and senescent cells.
- Inhibits mitochondrial electron transport chain and complex I respiration.
- Reduces mitochondrial membrane potential in targeted cells.
- Induces apoptosis in various breast cancer cell lines.
- Eliminates senescent cells in vivo and reduces senescence markers.
- Provided at high purity for research applications (≈98.6%).
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Medchemexpress LLC Z-LLY-FMK (Calpain Inhibitor IV) | 133410-84-1 | 98.7% | 557.65 | 100 MG
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Z-LLY-FMK (Calpain Inhibitor IV) is a calpain inhibitor involved in apoptosis of many cell systems. It inhibits intestine apoptosis after common bile duct ligation and reduces parasite burden in mice challenged with *Taenia crassiceps* cysts. It can be used for the study of cysticercosis.
- Calpain inhibitor
- Inhibits apoptosis in various cell systems
- Reduces parasite burden
- Used for cysticercosis studies
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Medchemexpress LLC (Z)-Zolucatetide ((Z)-FOG-001; I-67) | 98.2% | 2076.39 | 5 MG
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(Z)-Zolucatetide is a structural isomer of Zolucatetide and acts as a potent β-catenin inhibitor with an IC50 of <50 nM. It inhibits β-catenin and T-cell factor (TCF) transcription factor interaction, suppresses cell proliferation, and induces cell cycle arrest in target cells. It has shown anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts and can be used for the study of colon cancer.
- Potent β-catenin inhibitor with an IC50 of less than 50 nM.
- Inhibits β-catenin and T-cell factor (TCF) transcription factor interaction.
- Suppresses cell proliferation.
- Induces cell cycle arrest in target cells.
- Exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts.
- Useful for the study of colon cancer.
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Cayman Chemical 9 Z 12 Z 15 Z 18 Z 21 ZTetrac
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A very long-chain polyunsaturated fatty acid; has been used to study the desaturation and elongation of ω-3 polyunsaturated fatty acids; found at low levels in mouse brain and spleen and levels decrease in the brain and spleen of old and exceptionally old mice
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Medchemexpress LLC Z-3578 | 473687-20-6 | 98.72% | 467.37 | 50 MG
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Z-3578 | 473687-20-6 | 98.72% | 467.37 | 50 MG
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Chemscene CHEMSCENE
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NC3951712 S-2-AMINO-5-METHYLTHIOPENT
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Medchemexpress LLC Z-YVAD-AFC | 201608-13-1 | 98.85% | 811.76 | 25 MG
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Z-YVAD-AFC is a fluorescent substrate for Caspase-1, used to detect and measure its activity. It has a high purity of 98.85% and a molecular weight of 811.76. This product is provided as a solid for research use only.
- Fluorescent substrate for Caspase-1
- Detects and measures Caspase-1 activity
- High purity
- Available in various quantities
- For research use only
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000665867 Z-AZOXYSTROBIN 5MG
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