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Filtered Search Results
Medchemexpress LLC 7(Z),11(Z)-Heptacosadiene | 100462-58-6 | 99.9% | 376.70 | 10 MG
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7(Z),11(Z)-Heptacosadiene is an ester product that serves as a biochemical assay reagent for research purposes.
- Used for research
- Not intended for human use
- Not sold to patients
- Available in various quantities
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Medchemexpress LLC (E/Z)-Locostatin | 133812-16-5 | 99.5% | 245.27 | 5 MG
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(E/Z)-Locostatin is a racemic form of Locostatin, a potent RKIP inhibitor. It functions by binding to the Raf kinase inhibitor RKIP protein, thereby disrupting its interaction with Raf-1 kinase and G protein-coupled receptor kinase 2. This action leads to the inhibition of cell proliferation and migration.
- Inhibits cell proliferation and migration
- Disrupts RKIP interaction with Raf-1 kinase and G protein-coupled receptor kinase 2
- Suitable for research into cancer and digestive system diseases
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Medchemexpress LLC (E/Z)-GSK5182 | 2699724-40-6 | 98.9% | 417.54 | 50 MG
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(E/Z)-GSK5182 is a racemic compound of (E)-GSK5182 and (Z)-GSK5182 isomers. It is a highly selective and orally active inverse agonist of estrogen-related receptor γ (ERRγ) with an IC50 of 79 nM. It also induces reactive oxygen species (ROS) generation in hepatocellular carcinoma.
- Racemic compound.
- Highly selective and orally active.
- Inverse agonist of estrogen-related receptor γ (ERRγ) with an IC50 of 79 nM.
- Induces reactive oxygen species (ROS) generation in hepatocellular carcinoma.
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Apexbio Technology LLC Z-VDVAD-FMK 210344-92-6 25mg
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Z-VDVAD-FMK (CAS 210344-92-6) is an irreversible cell-permeable inhibitor primarily targeting caspase-2 with additional inhibitory effects on caspases-3 and -7 It functions by binding covalently to the active site of caspase enzymes thereby interrupting downstream apoptotic signaling processes In cellular studies treatment with Z-VDVAD-FMK suppresses caspase-2-dependent cytochrome c release triggered by apoptotic inducers such as etoposide Moreover Z-VDVAD-FMK effectively reduces apoptosis-related responses including cellular detachment DNA fragmentation and cleavage of PARP2 in endothelial cells exposed to oxyhemoglobin This small molecule serves as a pivotal tool for dissecting caspase pathways and investigating apoptosis-mediated cellular outcomes in biomedical research
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Medchemexpress LLC Tyrphostin AG490 | 134036-52-5 | MFCD00236452 | 99.7% | 294.30 | C17H14N2O3 | 1 ML
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(E/Z)-AG490 is a racemic mixture of the E and Z isomers of AG490, a small-molecule tyrosine kinase inhibitor used in biochemical and cellular research. It is employed to probe JAK/STAT signaling and related pathways due to reported inhibition of JAK2/3, STAT3, and EGFR.
- Racemic mixture of E and Z isomers.
- Small-molecule tyrosine kinase inhibitor for signaling research.
- Reported to inhibit JAK2/3, STAT3, and EGFR.
- Available as a concentrated solution for cell-based assays (10 mM in DMSO).
- High purity, 99.71%.
- Molecular weight 294.30 and formula C17H14N2O3.
- Offered in multiple solid and solution formats for assay flexibility.
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Medchemexpress LLC Z-thiothixene | 3313-26-6 | MFCD00079574 | 443.63 | C23H29N3O2S2 | 25 MG
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(Z)-Thiothixene is the Z (cis) isomer of thiothixene provided as an analytical reference standard for research use. It serves as a reference material for method development and qualitative and quantitative analysis by HPLC, GC, and MS, and is typically supplied with batch documentation such as a certificate of analysis, SDS, and spectral data.
- Identifies as (Z)-thiothixene, CAS 3313-26-6.
- Molecular formula C23H29N3O2S2; molecular weight 443.63.
- Intended for analytical applications and method development.
- Supplied with batch-specific certificate of analysis and supporting spectral data.
- Suitable for HPLC, GC, and mass spectrometry workflows.
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Medchemexpress LLC Z-levd-fmk | 1135688-25-3 | MFCD08703607 | 98.0% | 652.71 g/mol | C31H45FN4O10 | 5 MG
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Z-LEVD-FMK is a cell-permeable, irreversible caspase-4 inhibitor used for apoptosis and endoplasmic reticulum (ER) stress research. It has been reported to block ER stress-induced apoptosis in cancer cell models and is supplied as a high-purity solid intended for laboratory studies.
- Cell-permeable inhibitor suitable for intracellular assays.
- Blocks ER stress-induced apoptosis in cell models.
- High purity for reproducible biochemical and cellular experiments.
- Supplied as a stable solid with defined storage recommendations.
- Available in small research-scale pack sizes for lab use.
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Medchemexpress LLC (Z,E)-9,12-tetradecadien-1-ol | 42521-46-0 | MFCD00270832 | >95.0% | 210.36 g/mol | C14H26O | 1mL
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(Z E)-9 12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction[1]
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Medchemexpress LLC (E/Z)-MitoTam iodide, hydriodide | 98.6% | 999.82 g·mol⁻¹ | C52H60I2NOP | 5 MG
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(E/Z)-MitoTam iodide, hydriodide is the E/Z isomeric mixture of a tamoxifen-derived mitochondrial electron transport chain inhibitor used in research to disrupt mitochondrial respiration, alter mitochondrial morphology, and induce apoptosis in cancer and senescent cells.
- Inhibits mitochondrial electron transport chain and complex I respiration.
- Reduces mitochondrial membrane potential in targeted cells.
- Induces apoptosis in various breast cancer cell lines.
- Eliminates senescent cells in vivo and reduces senescence markers.
- Provided at high purity for research applications (≈98.6%).
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eMolecules (4R)-N-Cbz-4-hydroxy-azepane | 1017575-76-6 | MFCD11975381 | 1g
J & W PharmLab LLC | (4R)-N-Cbz-4-hydroxy-azepane | 1g | 482942643 | 60R0732 | 96.000 | 1017575-76-6 | MFCD11975381 | 249.310 | C14H19NO3
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Cayman Chemical 9 Z-TrIcosen 5g
An insect pheromone used in pesticides; activates antennal basiconic Or7a receptors in Drosophila; produced by honey bees to communicate information about food sources
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Apexbio Technology LLC Z-FY-CHO 167498-29-5 1mg
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Z-FY-CHO (CAS 167498-29-5) is a potent and selective inhibitor of cathepsin L exhibiting an IC50 of 0 85 nM It demonstrates significantly higher selectivity for cathepsin L over cathepsin B (IC50 85 1 nM) and cathepsin K (IC50 184 nM) In cellular assays Z-FY-CHO shows cytotoxic activity against Trypanosoma brucei (ED50 45 nM) with markedly reduced effects on human HL-60 cells (ED50 21 500 nM) The compound completely inhibits osteoclast-mediated bone resorption at 1 g/ml In murine osteoporosis models Z-FY-CHO produces dose-dependent inhibition of bone loss at 2 5 10 mg/kg This inhibitor serves as a valuable tool for investigating cathepsin L function in proteolysis parasitic infection and bone resorption studies
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Medchemexpress LLC E/Z-HA155 5mg | 1229652-22-5 | 5 MG
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(E/Z)-HA155 is a small-molecule autotaxin (ATX) type I inhibitor used in preclinical research to study cancer, fibrotic diseases, inflammation, pain, and angiogenesis. Supplied as a high-purity powder with recommended cold storage, it is available in multiple pack sizes and as a DMSO solution for biological assays.
- High purity: 99.3% (rounded from manufacturer specification).
- Molecular weight approximately 463.29 g·mol⁻¹.
- Chemical formula C24H19BFNO5S.
- Recommended storage: powder at -20°C; solutions at -80°C for long-term storage.
- Available in small research quantities and as a 10 mM solution in DMSO for assay use.
- Supplied with a certificate of analysis and safety data sheet for quality and handling information.
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Medchemexpress LLC 4-(Hydroxymethyl)benzeneboronic acid | 59016-93-2 | 151.96 | 25 G
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4-(Hydroxymethyl)benzeneboronic acid is an important intermediate used for the synthesis of other active compounds and is involved in the synthesis of tetrahedral boronate ester. It is for research use only and serves as a laboratory chemical and for the manufacture of substances.
- Important intermediate for active compound synthesis
- Involved in the synthesis of tetrahedral boronate ester
- Suitable for laboratory chemical applications
- Used in the manufacture of substances
- Store powder at -20°C for 3 years, 4°C for 2 years
- Store in solvent at -80°C for 6 months, -20°C for 1 month
- Appearance: Solid, white to off-white
- Stable under recommended storage conditions
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Medchemexpress LLC HY-19836 10mg Medchemexpress, PF-06650833 CAS:1817626-54-2 Purity:>98%
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Medchemexpress, HY-19836 10mg PF-06650833 CAS:1817626-54-2 PF-06650833 is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC50s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. PF-06650833 is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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