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Filtered Search Results
Medchemexpress LLC Aminooxy-PEG4-C2-Boc | 2100306-82-7 | >98% | C15H31NO7 | 100 MG
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Aminooxy-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase.
- The other ligand is for the target protein.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
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Chemscene CHEMSCENE
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5000576209 R-3-TERT-BUTOXYCARBONYL A 100G
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Medchemexpress LLC 1-Boc-4-(4-aminobutyl)piperazine | 745048-07-1 | MFCD04038543 | 95.0% | 257.37 g/mol | C13H27N3O2 | 250 MG
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1-Boc-4-(4-aminobutyl)piperazine is a Boc-protected piperazine derivative used as a chemical intermediate in medicinal chemistry for the synthesis of bioactive compounds. It is typically supplied in laboratory-scale quantities and is used where a protected primary amine is required for subsequent coupling or deprotection steps.
- Boc-protected piperazine scaffold for selective functionalization.
- Suitable as a building block in drug synthesis.
- Typical purity reported at 95%.
- Molecular weight about 257.37 g/mol and formula C13H27N3O2.
- Physical appearance: oil, colorless to light yellow.
- Recommended storage: protect from light; cool storage advised for long term.
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Medchemexpress LLC N- t-Boc-Aminooxy-PE | 25MG
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N- t-Boc-Aminooxy-PE | 25MG
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Aobchem AOBCHEM
5001004147 3-METHOXY-4- PYRROLIDINE-1-CA
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Medchemexpress LLC DEX-maleimide | 2754462-35-4 | >99.8% | C29H36FN3O7 | 100 MG
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DEX-maleimide is a versatile coupling agent designed for the synthesis of conjugates. It plays a crucial role in conjugating single-domain antibodies with various antigens and anti-inflammatory agents, offering significant utility in biochemical research.
- Can be used to synthesize conjugates
- Useful in research on autoimmune diseases
- Facilitates the conjugation of single-domain antibodies with antigens
- Aids in the conjugation of single-domain antibodies with anti-inflammatory agents
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Medchemexpress LLC Azido-PEG8-azide | 361543-07-9 | 98.2% | 464.51 | 100 MG
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Azido-PEG8-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This click chemistry reagent features an Azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that have DBCO or BCN groups.
- Functions as a click chemistry reagent
- Features an azide group
- Compatible with CuAAc reactions
- Compatible with SPAAC reactions
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Aobchem AOBCHEM
5001004618 PYRROLIDIN-1-YL M-TOLYL METHAN
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Medchemexpress LLC (Rac)-XL177A | 2417089-73-5 | 861.47 | 50 MG
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(Rac)-XL177A is the racemic isomer of XL177A, a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM. It induces cancer cell-killing effects through a p53-dependent mechanism.
- Racemic isomer of XL177A.
- Highly potent and selective irreversible USP7 inhibitor.
- IC50 of 0.34 nM.
- Elicits cancer cell-killing effects via a p53-dependent mechanism.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000783952 5-HYDROXYMETHYL-2-FU 50G
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eMolecules EMOLECULES INC
5000841784 Z-N-11-ETHYL-12-2-1-M 1G
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Aobchem AOBCHEM
5001091270 1- 3 5-DIBROMOPHENYL PYRROLIDI
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Medchemexpress LLC N-(azido-PEG2)-N-Boc-PEG3-NHS ester | 2093153-85-4 | 97.0% | C24H41N5O11 | 100 MG
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N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring an Azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
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Medchemexpress LLC HY-B0592 10mg Medchemexpress, Trandolapril CAS:87679-37-6 Purity:>98%
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Medchemexpress, HY-B0592 10mg Trandolapril CAS:87679-37-6 Trandolapril (RU44570) is a nonsulfhydryl prodrug that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 2-Pyridinamine, 5,6-bis(4-methoxy-3-methylphenyl)- | 2306039-66-5 | 99.8% | C21H22N2O2 | 100 MG
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WSB1 Degrader 1 is a potent and orally active WSB1 (WD repeat and SOCS box-containing 1) degrader, exhibiting anticancer metastatic effects.
- Induces WSB1 degradation in H1299-WSB1 cells.
- Exhibits potent antimigration efficacy in KHOS and H460 cell lines.
- Significantly inhibits cancer cell migration under normoxia and hypoxia in KHOS cells.
- Elevates RhoGDI2 protein levels in KHOS cells under hypoxia.
- Significantly inhibits wound-healing of H1299-WSB1 cells.
- Blocks wound-healing capability of wild-type A2780 cells.
- Effectively inhibits pulmonary metastasis of cancer cells in mice bearing highly metastatic 4T1 breast cancer cells.
- Shows quick absorption and acceptable blood exposure in rats after oral or intraperitoneal dosing.
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