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Filtered Search Results
Medchemexpress LLC 3-Maleimidopropionic acid | 7423-55-4 | 99.83% | 169.13 | 500 MG
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3-Maleimidopropionic acid is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs. These compounds facilitate the selective degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system. For research use only.
- Alkyl chain-based PROTAC linker
- Facilitates synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Sennoside B | 128-57-4 | 99.2% | 862.74 g/mol | C42H38O20 | 10 MG
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Sennoside B is an anthraquinone glycoside used for research into PDGFR signaling and gastroprotective effects. It is provided as a solid with high purity and is soluble in DMSO for in vitro studies.
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Medchemexpress LLC 6-MALEIMIDOHEXANOIC 1G
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5000203509 6-MALEIMIDOHEXANOIC 1G
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Medchemexpress LLC MCMMAF 25MG
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5000204259 MCMMAF 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656246 BIOTIN-C2-MALEIMIDE 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656257 ATTO 488 MALEIMIDE 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000657007 N-ETHYLMALEIMIDE 10MM/1ML
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Medchemexpress LLC N-Ethylmaleimide | 128-53-0 | 200 MG
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N-Ethylmaleimide (NEM) is derived from maleic acid and can alkylate free sulfhydryl groups. It acts as an irreversible cysteine protease inhibitor. NEM specifically inhibits phosphate transport in mitochondria and inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. It can be used to modify cysteine residues in proteins and peptides, and is also a deubiquitinating enzyme inhibitor.
- Irreversible cysteine protease inhibitor
- Specifically inhibits phosphate transport in mitochondria
- Inhibits prolyl endopeptidase (IC50 value of 6.3 μM)
- Modifies cysteine residues in proteins and peptides
- Deubiquitinating enzyme inhibitor
- Inhibits Akt phosphorylation
- Affects pro-caspase-3 conversion
- Promotes vascular smooth muscle cell apoptosis
- Affects PP2A activity and ROS production
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Medchemexpress LLC MC-VA-PABC-MMAE | 1818864-51-5 | 99.9% | 1230.53 | C65H99N9O14 | 5 MG
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MC-VA-PABC-MMAE is an agent-linker conjugate used in antibody-drug conjugate (ADC) research that links a peptide-based cleavable linker to the cytotoxic payload monomethyl auristatin E (MMAE). The material is supplied as a white to off-white solid for research use only and is intended for in vitro ADC assembly and evaluation.
- Contains a peptide MC-VA-PABC linker coupled to MMAE.
- High purity suitable for research applications.
- Molecular weight approximately 1230.53 Da.
- Chemical formula C65H99N9O14.
- Supplied as a solid, white to off-white in appearance.
- Store sealed at -20°C; in solvent store at -80°C for long-term.
- For research use only; not for human or clinical use.
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Chem-Impex International, Inc. 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | 55750-63-5 | MFCD00043043 | 1G
6-Maleimidohexanoic acid N-hydroxysuccinimide ester, 55750-63-5, MFCD00043043, 1G
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eMolecules 3-Maleimidopropionic acid | Ambeed | 7423-55-4 | MFCD00043030 | 169.136 | C7H7NO4 | 95.000 | OC(=O)CCN1C(=O)C=CC1=O | 10g | 525008566
3-Maleimidopropionic acid | Ambeed | 7423-55-4 | MFCD00043030 | 169.136 | C7H7NO4 | 95.000 | OC(=O)CCN1C(=O)C=CC1=O | 10g | 525008566
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Ambeed 1 2Hydroxyethyl 1Hpyrrole2 5di
1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione, 1585-90-6, 97%
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Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.31% | 369.54 | 25 MG
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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It can be used to modulate the effects of 2-arachidonyl glycerol (2-AG) by increasing its endogenous levels in the brain, and it prevents cerebellar membrane-mediated degradation of 2-AG.
- Potent, irreversible MAGL inhibitor
- Modulates effects of 2-arachidonyl glycerol (2-AG)
- Increases endogenous levels of 2-AG in the brain
- Prevents cerebellar membrane-mediated degradation of 2-AG
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eMolecules Bisindolylmaleimide V | 113963-68-1 | MFCD00236433 | 1g
Combi-Blocks | Bisindolylmaleimide V | 1g | 205390600 | OR-4244 | 98.000 | 113963-68-1 | MFCD00236433 | 341.370 | C21H15N3O2
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Medchemexpress LLC Bisindolylmaleimide X hydrochloride | 145317-11-9 | MFCD04972010 | >90.0% | 460.96 | C26H25ClN4O2 | 1 ML
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Bisindolylmaleimide X hydrochloride is a cell-permeable, reversible, ATP-competitive protein kinase C (PKC) inhibitor commonly used in biochemical and cell biology research to study kinase activity and signal transduction. Supplied as a ready-to-use solution, it facilitates rapid setup of in vitro assays; consult the supplier datasheet for handling and storage instructions.
- Potent protein kinase C inhibitor for biochemical assays.
- Cell-permeable and reversible mechanism of action.
- Provided as a ready-to-use high-concentration solution for immediate use.
- Suitable for kinase inhibition and signaling pathway studies.
- Follow supplier safety and storage recommendations for stability.
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