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Filtered Search Results
Medchemexpress LLC DEX-maleimide | 2754462-35-4 | >99.8% | C29H36FN3O7 | 100 MG
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DEX-maleimide is a versatile coupling agent designed for the synthesis of conjugates. It plays a crucial role in conjugating single-domain antibodies with various antigens and anti-inflammatory agents, offering significant utility in biochemical research.
- Can be used to synthesize conjugates
- Useful in research on autoimmune diseases
- Facilitates the conjugation of single-domain antibodies with antigens
- Aids in the conjugation of single-domain antibodies with anti-inflammatory agents
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TARGETMOL CHEMICALS INC Bisindolylmaleimide I 10MG
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Also available in 1 mL, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor, exhibiting a Ki of 14 nM. Purity 99.08%
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Medchemexpress LLC Bisindolylmaleimide V | 113963-68-1 | 97.8% | 341.36 | 250 MG
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Bisindolylmaleimide V is a cell-permeable negative control for protein kinase C inhibition studies with an IC50 value over 100 μM. It blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) *in vivo* with an IC50 of 8 μM. This compound is suitable for laboratory research involving protein kinase inhibition and S6K signaling pathways.
- Cell-permeable negative control for protein kinase C inhibition studies
- Blocks activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K)
- Useful for S6K signaling research
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eMolecules 2021179-11-1 | Medchem Express | MMAE-SMCC | 1mg | 694125024 | HY-135660 | 1140.45 | C58H89N7O14S
Ambeed | Sodium ((2R3S4R5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-34-dihydroxytetrahydrofuran-2-yl)methyl dihydrogentriphosphate | 1g | 490497503 | A117222 | 36051-68-0 | MFCD00078193 | 527.119 | C9H14N3Na2O14P3
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Cayman Chemical Bisindolylmaleimide I 10MG
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A highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM); competitive inhibitor for the ATP binding site of PKC; highly selective for PKCα, β1, β2, γ, δ, and ε isozymes; inhibits GSK3 in primary adipocyte lysates (IC50 = 360 nM) and in GSK3β immunoprecipitates derived from rat epididymal adipocytes (IC50 = 170 nM); competitively antagonizes the 5-HT3 receptor with a Ki value of 61 nM
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Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.31% | 369.54 | 10 MG
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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It modulates the effects of 2-arachidonyl glycerol (2-AG) by increasing endogenous levels of 2-AG in the brain and preventing cerebellar membrane-mediated degradation of 2-AG.
- Potent, irreversible inhibitor of monoacylglycerol lipase (MAGL)
- Modulates effects of 2-arachidonyl glycerol (2-AG)
- Increases endogenous levels of 2-AG in the brain
- Prevents cerebellar membrane-mediated degradation of 2-AG
- Produces hypothermia, inhibition of locomotor activity, antinociception, and catalepsy in vivo
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Medchemexpress LLC Maleimide-nota | 1295584-83-6 | MFCD32689663 | 99.3% | 425.44 g/mol | C18H27N5O7 | 25 MG
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Maleimide-NOTA is a bifunctional NOTA-derived chelator for labeling peptides and antibodies via cysteine conjugation. It contains a thiol-reactive maleimide group for selective reaction with cysteine residues and a NOTA macrocycle for chelation of metal ions used in radiolabeling and imaging applications.
- thiol-selective maleimide functional group for cysteine conjugation.
- NOTA macrocycle suitable for radiometal and metal chelation.
- reported high purity in supplier documentation.
- available in small research pack sizes, including 25 mg.
- use for peptide and antibody labeling in preclinical and imaging research.
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Medchemexpress LLC 1H-Pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester | 87981-04-2 | 98.0% | 378.42 | 50 MG
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Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs incorporate two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other for the protein of interest, thereby employing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Purity: 98.0%
- Molecular weight: 378.42
- Formula: C19H26N2O6
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Powder at -20°C for 3 years; in solvent at -80°C for 6 months, or -20°C for 1 month
- Solubility: ≥ 100 mg/mL in DMSO (264.26 mM)
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eMolecules 360768-37-2 | Medchem Express | N-Ethylmaleimide-d5 | 1mg | 784544391 | HY-D0843S | MFCD06658755 | 130.158 | C6H7NO2
Medchem Express | CMPD101 | 5mg | 724441981 | HY-103045 | 865608-11-3 | MFCD30182336 | 466.468 | C24H21F3N6O
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eMolecules 876305-42-9 | Medchem Express | N-Arachidonyl maleimide | 10mg | 532149999 | HY-136562 | MFCD11521506 | 369.549 | C24H35NO2
Medchem Express | N-Arachidonyl maleimide | 10mg | 532149999 | HY-136562 | 876305-42-9 | MFCD11521506 | 369.549 | C24H35NO2
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Medchemexpress LLC Poly(2-hydroxyethyl methacrylate) (Mv 300000) | 25249-16-5 | 300000 (Average) | 1 G
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Poly(2-hydroxyethyl methacrylate) (Mv 300000) is a biocompatible, optically transparent, hydrophilic, and non-degradable polymer with excellent cytocompatibility, eliciting a minimal immunological response from host tissue. It can be used for different biomedical applications, such as bone tissue regeneration, wound dressings, and drug delivery. It also absorbs water or biological fluids via its hydrophilic pendant groups to form a hydrogel.
- Used for bone tissue regeneration, wound dressings, and drug delivery
- Forms a hydrogel for applications like soft contact lenses, tissue regeneration, and cancer research
- Can be loaded with Quercetin (QT) to synthesize QT-PHEMA-GelCryoMem for antimicrobial activity
- Used in the synthesis of spongy materials with antimicrobial properties for wound and burn dressing applications
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Ambeed AMBEED
5000885749 S-1-BOC-2-HYDROXYMETHYLP 5G
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Ambeed AMBEED
5000882317 2-AMINO-5-CYANO-N3-DIMET 5G
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Ambeed AMBEED
5000897167 1-BOC-3-ETHYNYLPYRROLIDI 250MG
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eMolecules 193269-78-2 | 1-Boc-3-aminoazetidine | Advanced ChemBlocks | MFCD01861753 | 172.228 | C8H16N2O2 | 97.000 | CC(C)(C)OC(=O)N1CC(N)C1 | 25g | 112238162
1-Boc-3-aminoazetidine | Advanced ChemBlocks | 193269-78-2 | MFCD01861753 | 172.228 | C8H16N2O2 | 97.000 | CC(C)(C)OC(=O)N1CC(N)C1 | 25g | 112238162
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