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Filtered Search Results
Medchemexpress LLC Pmx-53 (Ac-Phe-Orn-Pro-dCha-Trp-Arg; lactam bridge Orn2-Arg6) | 219639-75-5 | 896.09 | C47H65N11O7 | 5 MG
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PMX-53 is a synthetic cyclic peptidic antagonist of the complement C5a receptor (C5aR1) used in research on immunology and inflammation. It is orally active and shows potent receptor inhibition (IC50 ≈ 20 nM). Chemical identifiers include CAS 219639-75-5 and molecular weight 896.09; sequence: Ac-Phe-{Orn}-Pro-{dCha}-Trp-Arg (lactam bridge Orn2-Arg6).
- Orally active C5a receptor antagonist with potent in vitro activity.
- Applicable to studies of complement-mediated inflammation, cancer, and atherosclerosis.
- Cyclic peptidic structure with a defined sequence and lactam bridge for stability.
- High solubility in DMSO and water for in vitro preparation.
- Stable under sealed, low-temperature storage; specific solvent storage lifetimes provided.
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Medchemexpress LLC (Z)-thiothixene | 3313-26-6 | MFCD00079574 | 99.8% | 443.63 g/mol | C23H29N3O2S2 | 10 MG
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(Z)-Thiothixene is the Z-isomer of thiothixene provided as an analytical reference standard for research and analytical applications. It is described as a 5-HT (serotonin) receptor antagonist and is intended for receptor pharmacology, method development, and analytical validation. The compound has formula C23H29N3O2S2 and molecular weight 443.63 g/mol.
- Analytical reference standard for receptor pharmacology and method development.
- Z-isomer specificity for isomer-selective studies.
- High purity (>99.8%) confirmed by LCMS.
- Suitable for HPLC, GC, and MS analytical workflows.
- Supplied as a solid for convenient handling and storage.
- Molecular formula C23H29N3O2S2; molecular weight 443.63 g/mol.
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Medchemexpress LLC (2S)-octyl-α-hydroxyglutarate | 1391194-64-1 | MFCD29045545 | ≥98.0% | 260.33 g·mol⁻1 | C13H24O5 | 25 MG
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(2S)-Octyl-α-hydroxyglutarate is the octyl-ester derivative of the S-isomer of 2-hydroxyglutarate. It is used as a membrane-permeable research reagent and precursor to 2-hydroxyglutarate in cellular and biochemical studies, and is supplied as a solid with high reported purity for laboratory research (not for human use).
- Membrane-permeable precursor of 2-hydroxyglutarate.
- Supports cell-based and biochemical assays of metabolic pathways.
- Supplied as a solid with high reported purity (≥98%).
- Soluble in DMSO for assay preparation.
- Available in small milligram quantities for research workflows.
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Medchemexpress LLC (Z)-orantinib | 210644-62-5 | MFCD09743433 | 99.4% | 310.35 g/mol | C18H18N2O3 | 5 MG
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(Z)-Orantinib is the Z-isomer small-molecule inhibitor of VEGFR (Flk-1/KDR), PDGFRβ, and FGFR1 used in preclinical research to investigate angiogenesis and tumor growth inhibition. Supplied as an orange-red solid with high reported purity, it is intended for laboratory research use only. The compound is available in multiple solid pack sizes and as a DMSO solution, with recommended storage conditions for powder and solvent formats.
- ATP-competitive inhibitor of VEGFR, PDGFRβ, and FGFR1.
- Reported IC50s: Flk-1/KDR 2.1 μM; PDGFRβ 0.008 μM; FGFR1 1.2 μM.
- High purity suitable for in vitro biochemical and cellular assays.
- Available as solid powder and as 10 mM solution in DMSO.
- Storage conditions provided for powder and solvent preparations.
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Medchemexpress LLC (2S)-Octyl-α-hydroxyglutarate | 1391194-64-1 | MFCD29045545 | 95.0% | 260.33 | C13H24O5 | 1 MG
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A cell-permeable octyl-ester derivative of the S-isomer of 2-hydroxyglutarate intended for research use. It is used to deliver intracellular 2-hydroxyglutarate activity in cell-based studies and has been reported to increase DNA double-strand breaks in treated cells. For research use only.
- Cell-permeable ester to enhance cellular uptake.
- Models intracellular S-2-hydroxyglutarate activity.
- Useful for studying DNA damage and metabolic signaling pathways.
- Available in small research pack sizes for assay development.
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Medchemexpress LLC (2S)-Octyl-α-hydroxyglutarate | 1391194-64-1 | MFCD09836372 | ≥98.0% | 260.33 | C13H24O5 | 50 MG
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(2S)-Octyl-α-hydroxyglutarate is a cell-permeable, octyl-ester modified form of the S-isomer of 2-hydroxyglutarate intended for research use. It serves as a membrane-permeant precursor and analogue of L-2-hydroxyglutarate for biochemical and cell-based studies, supplied as a laboratory reagent.
- Membrane-permeant precursor of S-2-hydroxyglutarate.
- Chemical formula C13H24O5.
- Molecular weight 260.33 g/mol.
- Available as a solid 50 mg pack for research applications.
- Purity reported on the product page (conflicting entries of 95.0% and ≥98.0%).
- For research use only; not for clinical or therapeutic use.
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Medchemexpress LLC GSK-872 hydrochloride | 2703752-81-0 | MFCD30481302 | 99.2% | 419.95 g/mol | C19H18ClN3O2S2 | 1 ML
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GSK-872 hydrochloride is a potent, selective inhibitor of receptor-interacting protein kinase 3 (RIPK3). It binds the RIP3 kinase domain and inhibits kinase activity with IC50 values of 1.8 nM (binding) and 1.3 nM (kinase inhibition). Supplied at high purity as a 10 mM solution in DMSO, the compound is intended for biochemical and cell-based research into necroptosis and RIPK3 signaling.
- Potent RIPK3 inhibition (IC50 1.3-1.8 nM).
- High purity suitable for research (>99%).
- Supplied as a 10 mM solution in DMSO, 1 mL, ready to use.
- Suitable for biochemical and cell-based assays studying necroptosis.
- COA and SDS documentation available for quality and safety verification.
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eMolecules 3470-98-2 | 1-Butylpyrrolidin-2-one | Combi-Blocks, Inc. | MFCD00020876 | 141.214 | C8H15NO | 97.000 | CCCCN1CCCC1=O | 1kg | 869682734
1-Butylpyrrolidin-2-one | Combi-Blocks, Inc. | 3470-98-2 | MFCD00020876 | 141.214 | C8H15NO | 97.000 | CCCCN1CCCC1=O | 1kg | 869682734
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Chem-Impex International, Inc. N-Vinyl-2-pyrrolidone | MFCD00003197 | 250G
N-Vinyl-2-pyrrolidone, MFCD00003197, 250G
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eMolecules 83-25-0 | N-PhenylsucciniMide | Ambeed | MFCD00022587 | 175.187 | C10H9NO2 | 98.000 | O=C1CCC(=O)N1c1ccccc1 | 1g | 506388860
N-PhenylsucciniMide | Ambeed | 83-25-0 | MFCD00022587 | 175.187 | C10H9NO2 | 98.000 | O=C1CCC(=O)N1c1ccccc1 | 1g | 506388860
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Cayman Chemical 4-carboxy TEMPO 500mg
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A spin label; reacts with ROS to monitor ROS production in vivo using ESR spectroscopy
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Chem-Impex International, Inc. (R)-(-)-Boc-3-pyrrolidinol | 109431-87-0 | MFCD01317838 | 25G
(R)-(-)-Boc-3-pyrrolidinol, 109431-87-0, MFCD01317838, 25G
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Chem-Impex International, Inc. N-Chlorosuccinimide | 128-09-6 | MFCD00005511 | 5KG
N-Chlorosuccinimide, 128-09-6, MFCD00005511, 5KG
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Chem-Impex International, Inc. 2-(4-Methoxyphenyl)pyrrolidine | MFCD01631836 | 1G
2-(4-Methoxyphenyl)pyrrolidine, MFCD01631836, 1G
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Chem-Impex International, Inc. N-Ethylmaleimide | 128-53-0 | MFCD00005509 | 25G
N-Ethylmaleimide, 128-53-0, MFCD00005509, 25G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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