Pyrrolidines

Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that form a cyclic secondary amine.

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6,001 – 6,015 of 6,176 results

6,001

Medchemexpress LLC (2s)-sb02024 (sb02877), s-enantiomer of sb02024 | 2126737-29-7 | 98.1% | 345.36 | 1 MG

(2S)-SB02024 is the S-enantiomer of the compound SB02024 and functions as an inhibitor of Vps34. Its inhibition of Vps34 has been shown to reprogram cold tumors into hot inflamed tumors and improve anti-PD-1/PD-L1 immunotherapy, suggesting its potential in cancer treatment research.

Functions as a Vps34 inhibitor.
Reprograms cold tumors into hot inflamed tumors.
Enhances anti-PD-1/PD-L1 immunotherapy.

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6,002

Medchemexpress LLC (1R,3S)-RSL3 | 1219810-13-5 | 99.8% | 440.88 | C23H21ClN2O5 | 25 MG

(1R,3S)-RSL3 is the less-active enantiomer of RSL3 used as a research reagent to study ferroptosis and GPX4-related mechanisms. In cellular assays it induces cell death in HT22 wild-type cells with an EC50 of 5.2 μM and is commonly used as a comparator to the more active enantiomer.

Chiral enantiomer used as a control in ferroptosis studies.
Induces cell death in HT22 cells (EC50 5.2 μM).
Molecular formula C23H21ClN2O5; molecular weight 440.88.
High purity (99.78%).
Supplied in small-mass quantities suitable for cellular assays.

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6,003

Apexbio Technology LLC N-3-oxo-dodecanoyl-L-Homoserine lactone(Synonyms: 3-Oxo-C12-HSL, N-(3-Oxododecanoyl)-L-homoserine lactone, OdDHL, 3-Oxododecanoyl homoserine lactone), 1mg, CAS: 168982-69-2.

N-3-oxo-dodecanoyl-L-Homoserine lactone (CAS 168982-69-2) commonly termed 3-O-C12-HSL is an acylhomoserine lactone (AHL) molecule utilized by Gram-negative bacteria such as Pseudomonas aeruginosa for quorum sensing This small lipid-soluble signaling molecule modulates virulence gene expression in response to bacterial population density In human pulmonary epithelial (16HBE) and lung fibroblast (L828) cell models exposure to 3-O-C12-HSL strongly elevates IL-8 transcription and secretion subsequently promoting neutrophil chemotaxis Thus 3-O-C12-HSL is extensively studied in pathogen-host interactions notably in respiratory infections associated with cystic fibrosis

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6,004

Medchemexpress LLC 1-Methylpyrrolidine | 120-94-5 | >=95.0% | 1 G

1-Methylpyrrolidine is an analytical standard intended for research and analytical applications. This methylated pyrrolidine can be used as a precursor to synthesize polyfluorinated pyrrolidine derivatives.

Used in qualitative, quantitative, and methodological research experiments
Compatible with techniques such as HPLC, GC, and MS

Pricing & Availability

6,005

eMolecules 127199-14-8 | (1S,2S)-2-fluorocyclopropane-1-carboxylic acid | Synthonix104.080 | C4H5FO2 | 97.000 | OC(=O)[C@@H]1C[C@@H]1F | 10g | 808556178

(1S,2S)-2-fluorocyclopropane-1-carboxylic acid | Synthonix | 127199-14-8104.080 | C4H5FO2 | 97.000 | OC(=O)[C@@H]1C[C@@H]1F | 10g | 808556178

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6,006

Ambeed AMBEED

5000849330 4- 2-CHLOROETHYL METHYL 250MG

Pricing & Availability

6,007

Medchemexpress LLC AA-T3A-C12 | 2938207-23-7 | 99.8% | 1059.72 | 50 MG

AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid) known for facilitating significant RNA delivery and transfection in activated fibroblasts. It enhances uptake of siRNA LNP by TGF-β-stimulated 3T3 fibroblasts and enables robust gene knockdown in in vitro studies. In vivo research shows AA-T3A-C12/siHSP47 LNP can significantly down-regulate HSP47 expression in fibrotic mice.

Anisamide ligand-tethered lipidoid (AA-lipidoid).
Mediates great RNA delivery.
Facilitates transfection of activated fibroblasts.
Enhances uptake of siRNA LNP by TGF-β-stimulated 3T3 fibroblasts.
Enables robust gene knockdown in activated fibroblasts.
Significantly down-regulates HSP47 expression in fibrotic mice when used as AA-T3A-C12/siHSP47 LNP.

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6,008

Medchemexpress LLC 1-Methylpyrrolidine | 120-94-5 | 99.0% | 500 MG

1-Methylpyrrolidine is a methylated pyrrolidine used as a precursor for synthesizing polyfluorinated pyrrolidine derivatives. It is a colorless to light yellow liquid with a density of 0.819 g/cm³. The molecular weight is 85.15 and its chemical formula is C₅H₁₁N. This product is for research use only.

Purity: 99.02%
Molecular weight: 85.15
Chemical formula: C₅H₁₁N
Appearance: Liquid
Color: Colorless to light yellow
SMILES: CN1CCCC1
Storage for pure form: -20°C for 3 years
Storage in solvent: -80°C for 6 months, -20°C for 1 month
In vitro solubility: 100 mg/mL in DMSO
In vivo solubility: ≥ 2.5 mg/mL in various protocols

Pricing & Availability

6,009

Medchemexpress LLC Bodipy-C12 | 1029138-21-3 | 99.8% | 452.39 | C27H35BF2N2O | 10 MG

BODIPY-C12 is a boron-dipyrromethene fluorescent probe bearing a C12 lipophilic tail. The hydrophobic dye is sensitive to its local environment and is used in fluorescence-based assays to quantify microviscosity, critical micelle concentration, and critical micelle temperature.

Hydrophobic BODIPY dye with a C12 lipophilic tail.
Excitation 490 nm and emission 512 nm for green fluorescence.
High purity (~99.8%) suitable for sensitive fluorescence measurements.
Available in small laboratory quantities, including 10 MG packages.
Store solid at 4°C protected from light; in solvent store -80°C (6 months) or -20°C (1 month).

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6,010

Medchemexpress LLC Diethyl dihydroxysuccinate | 87-91-2 | MFCD00009143 | 100.0% | 206.19 | C8H14O6 | 1kg

(2R 3R)-Diethyl 2 3-dihydroxysuccinate (Diethyl tartrate) is utilized in food industry as a flavoring agent and acidity regulator and for this purpose is also used in wines[1]

Pricing & Availability

6,011

Medchemexpress LLC (2S,3R,E)-2-aminohexadec-4-ene-1,3-diol | 6982-09-8 | MFCD08703028 | 99.0% | 271 Da | C16H33NO2 | 5mg

(2S 3R E)-2-Aminohexadec-4-ene-1 3-diol is an ester product

Pricing & Availability

6,012

Medchemexpress LLC 2R 3R-E1R 25mg | 1400888-63-2 | 232.28 | C13H16N2O2 | 25 MG

(2R,3R)-E1R is an enantiomer of E1R that functions as a sigma-1 receptor positive allosteric modulator (Sig1R PAM). It is supplied for research use to support studies of cognition and memory disorders and is provided as a solid.

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6,013

eMolecules 3772-26-7 | Ambeed | N-isopropyl-2-pyrrolidone | 1g | 601096047 | A609754 | MFCD00015398 | 127.187 | C7H13NO

ChemScene | 2-(4-Fluorophenyl)cyclopropanamine hydrochloride | 100mg | 632300162 | CS-0157515 | 879324-66-0 | MFCD18089473 | 187.640 | C9H11ClFN

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

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6,014

Medchemexpress LLC Hydroxyethyl starch | 9005-27-0 | MFCD00131356 | 100.7% | 170-230 kDa | (C6H10O5)m(C2H5O)n | 100 G

Hydroxyethyl starch is a high-molecular-weight polysaccharide derivative supplied as a white to off-white powder for laboratory research use. It functions as a biochemical reagent and formulation component, offering controlled molecular weight and aqueous solubility for experimental and assay applications.

High molecular weight (170-230 kDa) suitable for viscosity and colloidal applications.
Supplied as a solid powder, white to off-white in appearance.
Soluble in water at approximately 100 mg/mL with ultrasonic assistance.
Stable when stored as powder at -20°C for up to 3 years; in solution store at -80°C for extended storage.
Provided for research use only; not for clinical or patient use.

Pricing & Availability

6,015

Medchemexpress LLC (Rac)-Shikonin | 54952-43-1 | 5 MG

(Rac)-Shikonin, also known as Shikalkin, is a compound that exhibits anti-tumor activity. It is notable for its ability to circumvent cancer agent resistance by inducing a necroptotic death pathway. This compound has shown similar potency against drug-sensitive cancer cell lines, such as MCF-7 and HEK293, as well as their drug-resistant counterparts that overexpress P-glycoprotein, Bcl-2, or Bcl-xL.

Possesses anti-tumor activity
Circumvents cancer agent resistance by induction of a necroptotic death
Shows similar potency against drug-sensitive and drug-resistant cancer cell lines
Should be stored as a solid at 4°C, protected from light
In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light

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Pyrrolidines

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Medchemexpress LLC (2s)-sb02024 (sb02877), s-enantiomer of sb02024 | 2126737-29-7 | 98.1% | 345.36 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (1R,3S)-RSL3 | 1219810-13-5 | 99.8% | 440.88 | C23H21ClN2O5 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-Methylpyrrolidine | 120-94-5 | >=95.0% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AA-T3A-C12 | 2938207-23-7 | 99.8% | 1059.72 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-Methylpyrrolidine | 120-94-5 | 99.0% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bodipy-C12 | 1029138-21-3 | 99.8% | 452.39 | C27H35BF2N2O | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Diethyl dihydroxysuccinate | 87-91-2 | MFCD00009143 | 100.0% | 206.19 | C8H14O6 | 1kg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (2S,3R,E)-2-aminohexadec-4-ene-1,3-diol | 6982-09-8 | MFCD08703028 | 99.0% | 271 Da | C16H33NO2 | 5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2R 3R-E1R 25mg | 1400888-63-2 | 232.28 | C13H16N2O2 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Hydroxyethyl starch | 9005-27-0 | MFCD00131356 | 100.7% | 170-230 kDa | (C6H10O5)m(C2H5O)n | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Rac)-Shikonin | 54952-43-1 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More