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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430161 CY7.5 MALEIMIDE 1MG
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Medchemexpress LLC (Rac)-Sograzepide | 168161-71-5 | 498.58 | 1 ML
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(Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid. Storage recommendations are -20°C for 3 years (powder) or 4°C for 2 years (powder), and -80°C for 2 years (in solvent) or -20°C for 1 year (in solvent).
- Antagonist of cholecystokinin B (CCK-B) receptor
- Reduces secretion of gastric acid
- Targets cholecystokinin receptor
- Involves GPCR/G protein and neuronal signaling pathways
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Medchemexpress LLC BOC-(1R,3S)-3-aminocyclopentane carboxylic acid | 161660-94-2 | 229.28 | 25 MG
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BOC-(1R,3S)-3-aminocyclopentane carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.
- Molecular formula: C11H19NO4
- Appearance: Solid
- Color: White to off-white
- Solubility (in vitro): DMSO 100 mg/mL (requires ultrasonic)
- Storage: Room temperature for 3 years; in solvent: -80°C for 2 years or -20°C for 1 year
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eMolecules METHYL N-BOC-4-OXOPIPERID 100G
5000225181 METHYL N-BOC-4-OXOPIPERID 100G
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Medchemexpress LLC Z-aevd-fmk | 1135688-47-9 | 95.0% | 610.63 | C28H39FN4O10 | 50MG
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Z-AEVD-FMK is a peptide-based caspase-10 inhibitor used in cell biology research to block caspase-10-mediated apoptotic signaling. It inhibits activation of Bid and the mitochondrial release of apoptosis-inducing factor (AIF), resulting in reduced apoptotic cell counts in treated cultures. The compound is supplied as a solid research reagent and should be stored protected from light and under inert atmosphere; solution storage recommendations vary by solvent.
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5000378490 DOTA-GA-MALEIMIDE 50MG
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eMolecules 9H-FLUOREN-9-YLMETHYL 2 25G
5000165703 9H-FLUOREN-9-YLMETHYL 2 25G
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Medchemexpress LLC PROTAC Bcl2 degrader-1 | 2378801-85-3 | 99.8% | 941.84 g/mol | C45H45BrN6O10S | 5MG
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PROTAC Bcl2 degrader-1 is a cereblon-based PROTAC that selectively induces degradation of anti-apoptotic proteins Bcl-2 and Mcl-1 by recruiting the CRBN E3 ligase. Supplied for research use only as a high-purity solid, it is intended for biochemical and cellular studies of targeted protein degradation and apoptosis.
- Potent degrader of Bcl-2 and Mcl-1 (Bcl-2 DC50 3 μM; IC50 4.94 μM; Mcl-1 IC50 11.81 μM).
- High purity for research use (99.8%).
- Soluble in DMSO up to 25 mg/mL; in vivo vehicle formulations reported.
- Well characterized molecular properties (MW 941.84 g/mol; formula C45H45BrN6O10S).
- Storage conditions provided to preserve stability (-80°C in solvent for up to 6 months; -20°C for short term).
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378323 DOTA-GA-MALEIMIDE 100MG
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Apexbio Technology LLC N-Ethylmaleimide (NEM) 128-53-0 25mg
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N-Ethylmaleimide (CAS 128-53-0) is a small molecule commonly utilized in biochemical research as a selective alkylating agent for sulfhydryl groups on cysteine residues in proteins By irreversibly modifying thiol groups N-Ethylmaleimide disrupts the function of enzymes and other proteins that depend on free cysteines for activity or structural integrity This property enables researchers to investigate thiol-dependent biochemical pathways study protein conformational changes and elucidate redox regulation mechanisms Its application extends to proteomics enzymology and the analysis of intracellular signaling processes involving cysteine-mediated modifications
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377481 INFIGRATINIB-BOC 50MG
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5000385118 RAC -NSC305787 HYD 10MM 1ML
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TARGETMOL CHEMICALS INC Z-PUGNAc 5MG
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Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. (Z)-PUGNAc, a potent O-GlcNAcase inhibitor more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-beta-N-acetylaminoglucosidase) and can be used to increase levels of O-GlcNAc on nuclear and cytoplasmic proteins in vivo. Purity 97.58%
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eMolecules N-Succinimidyl-S-acetylthioacetate | 76931-93-6 | MFCD00036891 | 250mg
Chem-Impex | N-Succinimidyl-S-acetylthioacetate | 250mg | 272386928 | 23028 | | 76931-93-6 | MFCD00036891 | 231.220 | C8H9NO5S
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Medchemexpress LLC Z-321 | 130849-58-0 | 99.7% | 344.47 | 5 MG
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Z-321 is a prolylendopeptidase (PEP) inhibitor. It has been shown to decrease the mean lordosis quotient (LQ) in treated groups. Specifically, a dose of 300 mg/kg Z-321 was effective in inhibiting lordosis behavior without disturbing locomotor activity in female rats.
- Inhibitor of prolylendopeptidase (PEP).
- Decreases sexual receptivity (mean lordosis quotient).
- Inhibits lordosis behavior without disturbing locomotor activity at 300 mg/kg.
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