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Filtered Search Results
Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 10 MG
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(Z)-Guggulsterone is a constituent of the Indian Ayurvedic medicinal plant *Commiphora mukul*. It inhibits the growth of human prostate cancer cells by causing apoptosis and inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis. It also acts as a potent FXR antagonist and reduces ACE2 expression and SARS-CoV-2 infection.
- Inhibits growth of human prostate cancer cells by causing apoptosis
- Inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis
- Acts as a potent FXR antagonist
- Reduces ACE2 expression
- Reduces SARS-CoV-2 infection
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Apexbio Technology LLC SU 9516 377090-84-1 5mg
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SU 9516 (CAS 377090-84-1) is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2) with an IC50 of 22 nM It exhibits markedly reduced activity against CDK1 CDK4 PKC p38 and PDGFR SU 9516 disrupts cell cycle progression by inhibiting CDK2-mediated phosphorylation of the retinoblastoma protein (pRb) and induces cell cycle arrest and apoptosis in various cancer cell lines including colon carcinoma and leukemia It has been shown to reduce levels of Cyclin D1 and CDK2 promote mitochondrial translocation of Bax cytochrome c release and activate caspase cascades SU 9516 serves as a valuable chemical probe for investigating CDK2 function and cell cycle regulation in cancer research
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Enzo Life Sciences Bisindolylmaleimide II (1mg). CAS: 137592-45-1
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PKC inhibitor. Formula: C27H26N4O2. MW: 438.5. Purity: ≥97% (HPLC). Appearance: Orange solid. Solubility: Soluble in DMSO or 100% ethanol. Long Term Storage: -20°C. Handling: Protect from light.
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Medchemexpress LLC (S)-2-Methylpyrrolidine-2-carboxylic acid | 42856-71-3 | 98.0% | C6H11NO2 | 10 G
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(S)-2-Methylpyrrolidine-2-carboxylic acid is a proline derivative recognized as a beneficial ergogenic dietary substance. It influences anabolic hormone secretion, the supply of fuel during exercise, and mental performance during stress-related tasks, while also helping prevent exercise-induced muscle damage.
- Proline derivative
- Recognized as an ergogenic dietary substance
- Influences anabolic hormone secretion
- Supports fuel supply during exercise
- Enhances mental performance during stress-related tasks
- Aids in preventing exercise-induced muscle damage
- Solid appearance, white to off-white
- Soluble in water at 100 mg/mL
- Recommended storage at 4°C, protected from light and under nitrogen
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000703497 RAC-CHEM-0199 10MM/1ML
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Medchemexpress LLC (Rac)-Apremilast | 253168-86-4 | 99.5% | 460.50 | 50 MG
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(Rac)-Apremilast ((Rac)-CC-10004) is the racemic mixture of Apremilast. It possesses anti-inflammatory properties and is utilized for research concerning inflammatory diseases, such as psoriasis.
- Racemic mixture of Apremilast.
- Exhibits anti-inflammatory properties.
- Useful for research on inflammatory diseases like psoriasis.
- Inhibits TNFalpha production in LPS-stimulated human PBMC with an IC50 of 0.19 μM.
- IC50 for hPDE4D is 0.3 nM.
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Medchemexpress LLC (R)-pyrrolidine-2-carboxylic acid ((+)-(R)-Proline) | 344-25-2 | MFCD00064317 | 98.0% | C5H9NO2 | 100 G
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(R)-pyrrolidine-2-carboxylic acid is a proline isomer that exhibits high renal and hepatotoxicity in rats. It can be used to study amino acid metabolism and toxicity mechanisms.
- Molecular weight: 115.13
- Appearance: Solid, white to off-white
- Soluble in H2O (25 mg/mL) and DMSO (2.78 mg/mL)
- Induces perihilar fibrosis and hepatocellular necrosis in SD rats at 50 mg/kg
- For research use only
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Medchemexpress LLC N-Boc-MeVal | 1268729-59-4 | 245.32 | 100 MG
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N-Boc-MeVal is an ADC linker featuring a BOC protecting group. It is intended for research use only and is categorized under Antibody-drug Conjugate/ADC Related pathways.
- ADC linker with BOC protecting group
- Intended for research use only
- Categorized under Antibody-drug Conjugate/ADC Related pathways
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Medchemexpress LLC Azido-PEG2-azide | 59559-06-7 | 98.1% | 200.20 | 100 MG
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Azido-PEG2-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Peg-based protac linker.
- Used in the synthesis of protacs.
- Click chemistry reagent containing an azide group.
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
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Ambeed AMBEED
5000868038 9-BOC-29-DIAZASPIRO5.5UNDE 1GR
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Medchemexpress LLC 6-TAMRA maleimide | 1508249-06-6 | 93.5% | 552.58 | 5 MG
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6-TAMRA maleimide is a fluorescent dye composed of the fluorescent group of an avidin derivative and a maleimide group.
- For research use only.
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Enzo Life Sciences ET A receptor antagonist [BQ-123]. sodium salt (1mg). CAS: 136553-81-6
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Highly potent and selective ETA antagonist. Formula: C31H42N6O7 . Na. MW: 633.7. Purity: ≥96%. Solubility: Soluble in water. Long Term Storage: -20°C. Use/Stability: Stable for at least 3 years after receipt when stored at -20°C. Stock solutions are stable for up to 3 months when stored at -20°C.
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Medchemexpress LLC (1R,3S)-RSL3 | 1219810-13-5 | 99.8% | 440.88 | C23H21ClN2O5 | 25 MG
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(1R,3S)-RSL3 is the less-active enantiomer of RSL3 used as a research reagent to study ferroptosis and GPX4-related mechanisms. In cellular assays it induces cell death in HT22 wild-type cells with an EC50 of 5.2 μM and is commonly used as a comparator to the more active enantiomer.
- Chiral enantiomer used as a control in ferroptosis studies.
- Induces cell death in HT22 cells (EC50 5.2 μM).
- Molecular formula C23H21ClN2O5; molecular weight 440.88.
- High purity (99.78%).
- Supplied in small-mass quantities suitable for cellular assays.
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eMolecules 3470-98-2 | 1-Butylpyrrolidin-2-one | Combi-Blocks | MFCD00020876 | 141.214 | C8H15NO | 97.000 | CCCCN1CCCC1=O | 100g | 267163273
1-Butylpyrrolidin-2-one | Combi-Blocks | 3470-98-2 | MFCD00020876 | 141.214 | C8H15NO | 97.000 | CCCCN1CCCC1=O | 100g | 267163273
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eMolecules 77-86-1 | 2-Amino-2-(hydroxymethyl)-1,3-propanediol | Chem-Impex | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 100g | 272384829
2-Amino-2-(hydroxymethyl)-1,3-propanediol | Chem-Impex | 77-86-1 | MFCD00004679 | 121.136 | C4H11NO3 | 99.000 | NC(CO)(CO)CO | 100g | 272384829
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