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(Rac)-BL-918 is the racemic form of BL-918, a small-molecule activator of UNC-51-like kinase 1 (ULK1) that promotes cytoprotective autophagy. It is intended for preclinical and in vitro research applications where modulation of autophagy or ULK1 activity is required; handle and store according to laboratory safety practices.
Racemic small-molecule activator of ULK1.
Induces cytoprotective autophagy in cellular models.
High purity: 98.9%.
Molecular weight 533.44 g/mol; formula C23H15F8N3OS.
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(Rac)-BL-918 is the racemic form of BL-918, a small-molecule activator of UNC-51-like kinase 1 (ULK1) that induces cytoprotective autophagy. It is provided as a powder for research use and is intended for studies of autophagy pathways and neurodegenerative disease models such as Parkinson's disease. Molecular formula C23H15F8N3OS; molecular weight 533.44; CAS 2435589-07-2.
Activates ULK1 to induce cytoprotective autophagy.
Racemic mixture suitable for research applications.
Offered as a powder for convenient handling and storage.
High reported purity (98.9%).
Recommended storage: powder at -20°C (long term) or 4°C (short term); in solvent at -80°C.
Available in small research scales (for example, 1 mg, 5 mg, 10 mg).
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Rac-BL-918 is the racemic form of BL-918, a small-molecule activator of UNC-51-like kinase 1 (ULK1) that induces cytoprotective autophagy. It is supplied for research use in solid and solution formats and is used in cellular assays investigating autophagy and neurodegenerative disease mechanisms. The product is provided with high reported purity suitable for biochemical and cell-based studies.
Racemic small-molecule activator of UNC-51-like kinase 1 (ULK1).
Induces cytoprotective autophagy in cellular models.
Available as solid powder and as DMSO solutions for assay preparation.
High reported purity suitable for research (≈98.9%).
Used in studies of autophagy and neurodegenerative disease mechanisms.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(Rac)-BL-918 is the racemic form of BL-918, a small-molecule activator of UNC-51-like kinase 1 (ULK1) that induces cytoprotective autophagy. Provided for research use, it is available as a solid or as a ready-to-use 10 mM solution in DMSO (1 mL) for cellular and preclinical studies probing autophagy and neurodegeneration pathways.
Molecular weight 533.44 g/mol
Chemical formula C23H15F8N3OS
CAS number 2435589-07-2
Purity 98.9%
Available as 10 mM solution in DMSO (1 mL) and in solid quantities
Activates ULK1 and induces autophagy in cellular assays
Intended for in vitro and preclinical research use
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SU 4312 (CAS 5812-07-7) is a racemic mixture comprising both (Z)- and (E)-isomers each exhibiting distinct receptor tyrosine kinase inhibitory profiles The (Z)-isomer selectively inhibits platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor 2 (VEGFR2/FLK-1) while the (E)-isomer targets PDGFR VEGFR2 epidermal growth factor receptor (EGFR) human epidermal growth factor receptor 2 (HER-2) and insulin-like growth factor 1 receptor (IGF-1R) SU 4312 is widely employed in studies investigating tumor angiogenesis cellular signal transduction pathways and the development of targeted therapies in cancer research
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KCC-07 is a potent and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. It prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1), inducing anti-proliferative BAI1/p53/p21 signaling. It exhibits anticancer activity.
Clearly inhibited medulloblastomas (MB) cell growth in vitro.
Largely abrogated MBD2 binding to the ADGRB1 promoter in BAI1-silent MB cells.
Treatment inhibited tumor growth and significantly extended the survival of MB xenografts in athymic nude mice.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
KCC-07 is a brain-penetrant small molecule inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that prevents MBD2 binding to methylated DNA and activates BAI1-p53-p21 signaling to produce antiproliferative effects. It is supplied as a solid and as a 10 mM solution in DMSO, with reported high purity and recommended storage conditions for research use.