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Filtered Search Results
Medchemexpress LLC Firmonertinib mesylate | 2130958-55-1 | 99.9% | 664.70 | 25 MG
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Firmonertinib mesylate is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. It inhibits EGFR active mutations and the T790M acquired resistant mutation. This compound has potential for research into cancer diseases, particularly advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.
- Orally active
- Mutant-selective
- Blood-brain barrier penetrant EGFR inhibitor
- Inhibits EGFR active mutations
- Inhibits T790M acquired resistant mutation
- Potential for research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation
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Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 10MG
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Dosimertinib-d5 mesylate is the deuterated mesylate salt of dosimertinib, a third-generation epidermal growth factor receptor (EGFR) inhibitor. Provided as a research-grade reference standard for preclinical and analytical applications; not for human or veterinary use.
- Deuterated internal standard for analytical assays and mass spectrometry.
- High purity: 99.4%.
- Molecular formula: C29H32D5N7O5S.
- Available in small pack sizes (1-100 mg) suitable for method development.
- Mesylate salt form for improved handling and stability.
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Medchemexpress LLC Almonertinib mesylate | 2134096-06-1 | 99.7% | 621.75 | 25 MG
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Almonertinib mesylate (HS-10296 mesylate) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows great inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). It is used for the research of non-small cell lung cancer, and can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R, and L861Q.
- Orally available
- Irreversible
- Third-generation EGFR tyrosine kinase inhibitor
- High selectivity for EGFR-sensitizing and T790M resistance mutations
- Great inhibitory activity against T790M, T790M/L858R and T790M/Del19
- Used for research of non-small cell lung cancer
- Inhibits EGFR sensitive mutations (G719X, del19, L858R, L861Q)
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568789 FLUOROTHYL-200MG
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000569506 APRONAL-200MG
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000570173 OXYCLOZANIDE-200MG
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000570556 T-1105-200MG
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Medchemexpress LLC Phentolamine mesylate | 65-28-1 | 99.9% | 500 MG
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Phentolamine mesylate is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptors. It expands blood vessels to reduce peripheral vascular resistance and can be used for the research of pheochromocytoma-related hypertension, heart failure, and erectile dysfunction.
- Reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptors
- Expands blood vessels to reduce peripheral vascular resistance
- Used for research in pheochromocytoma-related hypertension, heart failure, and erectile dysfunction
- High purity of 99.9%
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Medchemexpress LLC Danofloxacin mesylate | 119478-55-6 | MFCD00673687 | 99.9% | 100 MG
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Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. It exhibits broad-spectrum bactericidal activity primarily by inhibiting bacterial DNA gyrase and also functions as a substrate for ATP-dependent efflux transporters such as P-gp and MRP2.
- Used as a veterinary drug
- Broad-spectrum bactericidal activity
- Inhibits bacterial DNA gyrase
- Substrate for ATP-dependent efflux transporters (P-gp and MRP2)
- Targets P-glycoprotein and bacterial components
- Involves membrane transporter/ion channel and anti-infection mechanisms
- Effective against bovine bacterial respiratory pathogens
- Demonstrates asymmetric transport across Caco-2 cells
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Medchemexpress LLC Dihydroergocristine mesylate | 24730-10-7 | MFCD00153792 | ≥98.0% | 707.84 | C36H45N5O8S | 10 MG
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Dihydroergocristine mesylate is a research reagent reported to act as a γ-secretase inhibitor; it reduces production of amyloid-β peptides and binds directly to γ-secretase and nicastrin. It is supplied as the mesylate salt for use in neuroscience and Alzheimer's disease research.
- Acts as a γ-secretase inhibitor.
- Reduces production of amyloid-β peptides.
- Binds directly to γ-secretase and nicastrin.
- Supplied as the mesylate salt.
- Available in small research quantities suitable for analytical or in-vitro studies.
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Sigma Aldrich Fine Chemicals Biosciences Methysergide maleate salt solid | 129-49-7 | MFCD00083185 | 2MG
Methysergide maleate salt solid | Mol Wt: 469.53 | 129-49-7 | MFCD00083185 | 2MG
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Medchemexpress LLC 7-Nitroindazole | 2942-42-9 | 99.1% | C7H5N3O2 | 200 MG
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7-Nitroindazole | 2942-42-9 | 99.1% | C7H5N3O2 | 200 MG
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eMolecules 69812-30-2 | 2-ACETAMIDOTHIAZOLE-5-SULFONYL CHLORIDE | AstaTech | MFCD05022486 | 240.680 | C5H5ClN2O3S2 | 95.000 | CC(=O)Nc1ncc(s1)S(Cl)(=O)=O | 0.25g | 233631705
2-ACETAMIDOTHIAZOLE-5-SULFONYL CHLORIDE | AstaTech | 69812-30-2 | MFCD05022486 | 240.680 | C5H5ClN2O3S2 | 95.000 | CC(=O)Nc1ncc(s1)S(Cl)(=O)=O | 0.25g | 233631705
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eMolecules 288154-18-7 | tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Ambeed | MFCD04114477 | 243.307 | C11H21N3O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 1g | 552739296
tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Ambeed | 288154-18-7 | MFCD04114477 | 243.307 | C11H21N3O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 1g | 552739296
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eMolecules 72716-87-1 | 2-Methoxy-pyridine-4-carbaldehyde | Ochem Incorporation | MFCD06410680 | 137.138 | C7H7NO2 | 98.000 | COc1cc(C=O)ccn1 | 1g | 773157178
2-Methoxy-pyridine-4-carbaldehyde | Ochem Incorporation | 72716-87-1 | MFCD06410680 | 137.138 | C7H7NO2 | 98.000 | COc1cc(C=O)ccn1 | 1g | 773157178
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