Quinolines and derivatives
Medchemexpress LLC 7-bromoquinoline-4-carboxylic acid | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 g·mol⁻1 | C10H6BrNO2 | 100 MG
7-Bromoquinoline-4-carboxylic acid is a bromo-substituted quinoline carboxylic acid used as an intermediate and reagent in medicinal chemistry and organic synthesis. Manufacturer batch documentation provides molecular, analytical, and storage information to support research use and quality control.
- Contains a bromine-substituted quinoline core suitable for derivatization.
- Useful intermediate for medicinal chemistry and organic synthesis.
- Molecular formula C10H6BrNO2 and molecular weight 252.06 g·mol⁻1.
- Solid powder appearance; batch color may be gray to brown.
- Analytical data available, including HPLC purity and NMR confirmation.
- Recommended storage: powder at -20 °C for long term, 4 °C for shorter term; solutions at -80 °C for extended storage.
Medchemexpress LLC Azido-PEG23-amine | 2172677-19-7 | 99.93% | C48H98N4O23 | 50 MG
Azido-PEG23-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing an azide group that enables various cycloaddition reactions.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Medchemexpress LLC Trifluoperazine dihydrochloride | 440-17-5 | 99.9% | 50 MG
Trifluoperazine dihydrochloride is an antipsychotic agent that functions by blocking central dopamine receptors. It also acts as a potent α1-adrenergic receptor antagonist and a NUPR1 inhibitor, demonstrating anticancer activity. Furthermore, it is a calmodulin inhibitor and inhibits P-glycoprotein. This compound is utilized in research for schizophrenia and acts as a reversible inhibitor of influenza virus morphogenesis by interfering with cellular CaM and/or CaM-dependent functions.
- Blocks central dopamine receptors
- Potent α1-adrenergic receptor antagonist
- Potent NUPR1 inhibitor with anticancer activity
- Calmodulin inhibitor
- Inhibits P-glycoprotein
- Utilized in research for schizophrenia
- Acts as a reversible inhibitor of influenza virus morphogenesis
Medchemexpress LLC Peg-bis-amine (MW 2000) | 24991-53-5 | 99.4% | (C2H4O)nC4H12N2O | 250 MG
PEG-bis-amine (Poly(ethylene glycol)-bis-amine) (MW 2000) is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Can be used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- Ligands are for an E3 ubiquitin ligase and a target protein
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC 1,11-diamino-3,6,9-trioxaundecane | 929-75-9 | MFCD00628164 | 99.8% | 192.26 | C8H20N2O3 | 5 G
Amino-PEG3-C2-Amine is a short PEG-based linker containing three ethylene glycol units and a terminal primary amine. It is used as a building block for the synthesis of PROTACs and other bioconjugates, providing a hydrophilic, flexible spacer and a reactive amine handle for coupling chemistry. Supplied at high purity, the compound is intended for medicinal chemistry and linker construction workflows.
- Provides a short, flexible PEG3 spacer that improves solubility.
- Presents a terminal primary amine for efficient coupling to carboxyls or activated esters.
- High purity suitable for synthetic and medicinal chemistry applications.
- Available in multiple pack sizes for small-scale and preparative work.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC 5(6)-Carboxy-2',7'-dichlorofluorescein | 111843-78-8 | 99.0% | 100 MG
5(6)-Carboxy-2',7'-dichlorofluorescein is an ideal substrate for MRP2 vesicular transport assay, possessing excellent detection and transport properties.
- Ideal substrate for MRP2 vesicular transport assay
- Excellent detection and transport properties
Medchemexpress LLC Quin C1 | 786706-21-6 | 98.5% | 445.51 | 500 UG
Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). It significantly reduces neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue.
- Highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX)
- Significantly reduces neutrophil and lymphocyte counts in BALF
- Diminishes expression of TNF-α, IL-1β, KC, and TGF-β1
- Decreases collagen deposition in lung tissue
- Potential for research into lung injury
![eMolecules 957486-82-7 | Azido-PEG6-amine | ChemScene | MFCD03453240 | 350.416 | C14H30N4O6 | 97.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 250mg | 672544878](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000126202.jpg-250.jpg)
eMolecules 957486-82-7 | Azido-PEG6-amine | ChemScene | MFCD03453240 | 350.416 | C14H30N4O6 | 97.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 250mg | 672544878
Azido-PEG6-amine | ChemScene | 957486-82-7 | MFCD03453240 | 350.416 | C14H30N4O6 | 97.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 250mg | 672544878
Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 25 G
2-Aminoquinoline, also known as 2-Quinolinamine, is a promising compound primarily recognized as a bioavailable nNOS inhibitor. Despite exhibiting low human nNOS inhibition and selectivity against human eNOS, along with significant binding to other CNS targets, it demonstrates antiviral activity against the vaccinia virus. This compound holds potential for research in antineurodegenerative agents.
- Acts as a bioavailable nNOS inhibitor
- Shows antiviral activity against the vaccinia virus
- Potential for research into antineurodegenerative agents
- Appears as a solid
- For research use only
Medchemexpress LLC Anhydrous sodium dihydrogen phosphate, for molecular biology | 7558-80-7 | 99.9% | 10 G
Anhydrous sodium dihydrogen phosphate, for molecular biology, is an inorganic salt compound that can be used as a buffer and nutritional supplement. It is suitable for use in molecular biology experiments.
- Commonly used in industry and laboratories as a buffer, nutritional supplement, and cleaning agent.
- Plays a role in metal processing, pharmaceutical, and chemical industries.
- Can be utilized in water treatment and environmental protection as a purifying or precipitating agent for solutions.
eMolecules 4965-36-0 | 7-Bromoquinoline | Ambeed | MFCD03695823 | 208.058 | C9H6BrN | 98.000 | Brc1ccc2cccnc2c1 | 25g | 490534632
7-Bromoquinoline | Ambeed | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 98.000 | Brc1ccc2cccnc2c1 | 25g | 490534632
Medchemexpress LLC m-PEG8-amine | 869718-81-0 | MFCD13184961 | ≥98.0% | 383.48 g·mol⁻¹ | C17H37NO8 | 100 MG
m-PEG8-amine is an 8-unit monomethoxy polyethylene glycol (PEG) bearing a terminal primary amine used as a cleavable spacer/linker in antibody-drug conjugates and for general bioconjugation. It is supplied as a powder and is typically handled and stored according to the supplier's safety documentation.
- Chemical name: m-PEG8-amine
- Cas number: 869718-81-0
- Purity: ≥98.0%
- Molecular formula: C17H37NO8
- Molecular weight: 383.48 g·mol⁻¹
- Typical solubility: soluble in DMSO
- Available pack sizes: 50 MG, 100 MG, 500 MG, 1 G, 5 G, 10 G, 50 G
Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | 97.0% | C22H46N4O10 | 100 MG
Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups, and also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group for CuAAc and SPAAC reactions
- Enables reactions with alkyne, DBCO, or BCN groups
- Leverages the ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Benzyl-PEG5-amine | 86770-77-6 | 98.0% | C17H29NO5 | 250 MG
Benzyl-PEG5-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein intended for degradation. They leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Used in PROTAC synthesis
- PEG-based linker
- Facilitates selective protein degradation