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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences NMQ/N methyl quinidine M50MG
NMQ/N methyl quinidine M50MG
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Medchemexpress LLC Cinchonine | 118-10-5 | MFCD00064372 | 99.7% | 294.39 | C19H22N2O | 25g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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eMolecules 3413-58-9 | Medchem Express | Ethylhydrocupreine (hydrochloride) | 25mg | 673358916 | HY-136429A | 376.93 | C21H29ClN2O2
Ambeed | 8-Bromo-6-chloro-3-methylimidazo[12-a]pyrazine | 50mg | 521478261 | A760598 | 84066-11-5 | MFCD22576309 | 246.490 | C7H5BrClN3
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Apexbio Technology LLC Cinchonidine 485-71-2 500mg
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Cinchonidine (CAS 485-71-2) is a small-molecule inhibitor targeting the serotonin transporter (SERT) It is designed to inhibit SERT function thereby modulating serotonin uptake activity Cinchonidine exerts its biological activity primarily through SERT inhibition In in vitro studies Cinchonidine demonstrates inhibitory activity with IC50 values of 330 M for dSERT and 4 2 36 196 and 15 M for hSERT and its mutants I172M S438T and Y95F respectively Based on these pharmacological properties Cinchonidine holds research potential in serotonin transporter regulation and malaria research
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Abcam Quinine hemisulfate monohydrate, Potassium channel blocker, 25G
MW 391.47 g/mol. Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive and hypoglycemic agent. Inhibits mitochondrial ATP-regulated potassium channel. Also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
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Cayman Chemical 8 12isoiPF2aVId11
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An internal standard for the quantification of 8,12-iso-iPF2α-VI by GC- or LC-MS.
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Medchemexpress LLC 8-Aminoquinoline | 578-66-5 | MFCD00006809 | 144.17 | 5 G
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8-Aminoquinoline is a biochemical reagent. It can be utilized as a biological material or an organic compound for various life science-related research applications.
- Biochemical reagent
- Suitable for life science related research
- Can be used as a biological material
- Can be used as an organic compound
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | 295.18 | 5 MG
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L-Cystathionine dihydrochloride is a nonprotein thioether and a key amino acid involved in the metabolic state of sulfur-containing amino acids. It has been shown to protect against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). This suggests an important role for L-Cystathionine in cardiovascular protection.
- Key amino acid associated with the metabolic state of sulfur-containing amino acids
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs)
- Plays an important role in cardiovascular protection
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | MFCD00036665 | 99.9% | 295.18 | 25 MG
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L-Cystathionine dihydrochloride is an analytical standard intended for research and analytical applications. This nonprotein thioether is a key amino acid associated with the metabolic state of sulfur-containing amino acids. It protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs) and plays an important role in cardiovascular protection.
- Analytical standard grade for research and analytical applications.
- Nonprotein thioether and key amino acid.
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs).
- Plays an important role in cardiovascular protection.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Cayman Chemical 8 12isoiPF2aVI1 5lactone
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A racemic mixture of the lactone form of the free acid, 8,12-iso- iPF2α-VI; the free acid is the most abundant F2-iP2 regioisomer measured in the urine of rats treated to induce lipid peroxidation; used as a biomarker for oxidative stress
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Medchemexpress LLC Amifostine thiol dihydrochloride | 14653-77-1 | MFCD00460339 | >98.0% | 207.16 g·mol⁻¹ | C5H16Cl2N2S | 1 ML
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Amifostine thiol dihydrochloride (WR-1065 dihydrochloride) is the active thiol metabolite of amifostine used as a research reagent for radioprotection and cytoprotection. It is reported to protect normal tissues from the toxic effects of certain chemotherapeutic and radiotherapeutic agents and to activate p53 via a JNK-dependent signaling pathway, making it useful in studies of apoptosis, DNA damage response, and MDM2-p53 signaling.
- Cytoprotective and radioprotective research reagent suitable for cellular assays.
- Reported to activate p53 through a JNK-dependent signaling pathway.
- Provided as a ready-to-use 10 mM solution (1 mL) for experimental convenience.
- Also available in solid formats for formulation or analytical applications.
- Useful for apoptosis, DNA damage response, and MDM2-p53 pathway studies.
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Ambeed 2Chloro9Hpurine
2-Chloro-9H-purine, 1681-15-8, 97%
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eMolecules 99584-10-8 | 6-Amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one | ChemScene | MFCD07801206 | 164.164 | C8H8N2O2 | 95.000 | Cn1c2ccc(N)cc2oc1=O | 250mg | 680025320
6-Amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one | ChemScene | 99584-10-8 | MFCD07801206 | 164.164 | C8H8N2O2 | 95.000 | Cn1c2ccc(N)cc2oc1=O | 250mg | 680025320
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Selleck Chemical LLC Anti-CTLA-8-A2861-1MG-25
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Anti-CTLA-8 is a human monoclonal antibody against IL-17A (interleukin-17A) that can potently neutralize the effects of recombinant and native human IL-17A MW 143 72
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Medchemexpress LLC Azido-PEG12-amine | 2803478-25-1 | 98.0% | 614.73 g/mol | C26H54N4O12 | 50 MG
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Azido-PEG12-amine is a PEG12 linker with an azide group at one terminus and a primary amine at the other, designed for bioconjugation and click chemistry applications.
- Azide functionality enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Primary amine enables conjugation to activated carboxylates such as NHS esters.
- Molecular weight approximately 614.73 g/mol; formula C26H54N4O12.
- High purity by NMR (typically 98.0%).
- Water-soluble PEG12 linker suitable for linker synthesis, PROTACs, and ADCs.
- Store sealed at 4°C, protect from moisture and light.
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