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Filtered Search Results
Apexbio Technology LLC Oxymatrine 16837-52-8 200mg
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Oxymatrine (CAS 16837-52-8) is a quinolizidine alkaloid extracted from Sophora flavescens It has been shown to modulate multiple cellular pathways associated with fibrosis and neurodegeneration including inhibition of TGF- 1-mediated signaling and reduction of pro-inflammatory cytokine expression Oxymatrine exhibits antifibrotic and neuroprotective properties in various experimental models It is also extensively studied for its antiviral activity against hepatitis B virus and has been applied in traditional Chinese medicine for hepatitis management This compound is valuable for investigating mechanisms of fibrosis neuroprotection and viral pathogenesis
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Medchemexpress LLC Foliglurax monohydrochloride | 2133294-96-7 | MFCD31807615 | 98.6% | 457.97 | 100 MG
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Foliglurax monohydrochloride is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM), with an EC50 of 79 nM. It exhibits an antiparkinsonian effect.
- Highly selective and potent
- Brain-penetrant
- Metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM)
- EC50 of 79 nM
- Exhibits an antiparkinsonian effect
- Chemical formula: C23H24ClN3O3S
- Appearance: Solid
- Color: Light yellow to yellow
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Medchemexpress LLC Piperacillin sodium | 59703-84-3 | 98.22% | 200 MG
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Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic that exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. It is most commonly used in combination with the β-lactamase inhibitor Tazobactam.
- Exhibits potent bactericidal activity
- Effective against Gram-negative bacteria
- Effective against select Gram-positive strains
- Targets penicillin-binding proteins
- Commonly used with β-lactamase inhibitor
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Medchemexpress LLC Chlorcyclizine hydrochloride | 14362-31-3 | 99.8% | 337.29 | 200 MG
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Chlorcyclizine hydrochloride is a histamine H1 antagonist. This product is a solid with a white to off-white appearance.
- Has a purity of 99.77%.
- Soluble in DMSO at 77.5 mg/mL.
- Targets the histamine H1 receptor.
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Medchemexpress LLC MSA-2 | 129425-81-6 | 99.8% | 294.32 | 200 MG
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MSA-2 is a potent and orally available non-nucleotide STING agonist that binds to STING as a noncovalent dimer with nanomolar affinity. It stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models.
- Potent and orally available non-nucleotide STING agonist
- Binds to STING as a noncovalent dimer with nanomolar affinity
- Stimulates interferon-β secretion in tumors
- Induces tumor regression with durable antitumor immunity
- Synergizes with anti-PD-1 in syngeneic mouse tumor models
- Achieves comparable exposure in tumor and plasma
- Exhibits dose-dependent antitumor activity
- Induces elevations of IFN-β, IL-6, and TNF-α in tumors
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eMolecules 320349-89-1 | 2-HYDROXYQUINOLINE-7-CARBOXYLIC ACID | MFCD11557271 | 1g
ChemScene | (S)-2-((tert-Butoxycarbonyl)amino)-6-hydroxyhexanoic acid | 250mg | 632310608 | CS-0179118 | 77611-37-1 | MFCD01862292 | 247.291 | C11H21NO5
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Medchemexpress LLC Regorafenib (monohydrate) | 1019206-88-2 | MFCD17170366 | 99.9% | 500.8 g/mol | C21H17ClF4N4O4 | 500 MG
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Regorafenib monohydrate is a research-grade small-molecule multikinase inhibitor used in preclinical and biochemical research. The monohydrate form provides consistent physicochemical properties and is supplied with a certificate of analysis for identity and purity verification.
- Used as a multikinase inhibitor in biochemical and cellular assays.
- High purity suitable for analytical and pharmacology studies.
- Molecular formula C21H17ClF4N4O4; molecular weight 500.8 g/mol.
- Monohydrate form for consistent handling and characterization.
- Provided with COA and SDS for quality and safety documentation.
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Medchemexpress LLC Chlormethiazole hydrochloride | 6001-74-7 | MFCD00673948 | 99.9% | C6H9Cl2NS | 200 MG
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Chlormethiazole hydrochloride is a potent and orally active GABAA agonist, known for its ability to inhibit cytochrome P450 isoforms CYP2A6 and CYP2E1 in human liver microsomes. This compound acts as an anticonvulsant agent, showing potential for the treatment of convulsive status epilepticus. It is provided as a light yellow to yellow solid.
- Potent and orally active GABAA agonist
- Inhibits cytochrome P450 isoforms CYP2A6 and CYP2E1
- Anticonvulsant agent
- Soluble in DMSO and H2O
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![Medchemexpress LLC Benzeneacetonitrile, 4-[(4-methoxyphenyl)methoxy]- | 175135-47-4 | 98.1% | 253.30 | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000388214-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzeneacetonitrile, 4-[(4-methoxyphenyl)methoxy]- | 175135-47-4 | 98.1% | 253.30 | 200 MG
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O4I1 is a potent Oct3/4 inducer that enhances Oct3/4 gene expression, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation. It activates Oct3/4 at both transcriptional and translational levels in various human cell lines and is sufficient to enhance Oct3/4 overexpression by 2-fold and 3-fold after 48 and 72 hours of treatment, respectively.
- Potent Oct3/4 inducer.
- Enhances Oct3/4 gene expression.
- Increases Oct3/4 protein levels.
- Promotes Oct3/4 mediated transcriptional activation.
- Activates Oct3/4 at transcriptional and translational levels in diverse human cell lines.
- Can enhance Oct3/4 overexpression 2-fold and 3-fold after 48 and 72 hours of treatment in untransfected HEK293 cells.
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Medchemexpress LLC Oxymatrine | 16837-52-8 | 99.9% | 264.37 | 200 MG
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Oxymatrine | 16837-52-8 | 99.9% | 264.37 | 200 MG
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Medchemexpress LLC Regorafenib monohydrate | 1019206-88-2 | MFCD17170366 | 99.9% | 500.8 g/mol | C21H17ClF4N4O4 | 50 MG
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Regorafenib monohydrate is the monohydrate form of regorafenib, a multi-targeted receptor tyrosine kinase inhibitor used as a research reagent and analytical standard. It exhibits potent inhibition of VEGFR, PDGFR, KIT, RET, and RAF kinases and is used in preclinical assays to study antitumor and antiangiogenic activity.
- High purity (≈99.9%) suitable for analytical work.
- Monohydrate form with molecular weight 500.8 g/mol.
- Useful as an analytical standard and research reagent in kinase assays.
- Available in small, quantified laboratory packages for preclinical studies.
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Apexbio Technology LLC Tandutinib (MLN518) HCl 387867-13-2 (free base) 200mg
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Tandutinib MLN518 HCl is a small-molecule inhibitor targeting receptor tyrosine kinases including FLT3 PDGFR and c-Kit It is designed to inhibit these kinases by competitively interfering with their ATP-binding sites thereby suppressing downstream signaling pathways such as Akt/mTOR MAP kinase and PI3 kinase Tandutinib MLN518 HCl exerts its biological activity primarily through kinase inhibition In FLT3-ITD-positive acute myeloid leukemia (AML) cell models and colon cancer research models Tandutinib MLN518 HCl demonstrates inhibition of cell proliferation receptor autophosphorylation tumor cell growth colony formation and angiogenesis-related gene expression Based on these pharmacological properties Tandutinib MLN518 HCl holds research potential in investigating signaling mechanisms and therapeutic avenues in leukemia and solid tumors
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Medchemexpress LLC ROSIGLITAZONE HYDRO | 200MG
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ROSIGLITAZONE HYDRO | 200MG
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Medchemexpress LLC Lusutrombopag | 1110766-97-6 | 98.88% | 591.55 | 200 MG
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Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for the treatment of chronic liver disease. It acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels. This product is for research use only.
- Orally bioavailable TPO receptor agonist
- Treats chronic liver disease
- Selectively acts on human TPO receptor
- Promotes proliferation and differentiation of bone marrow cells
- Increases platelet levels
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Medchemexpress LLC N'-cyclohexyl-N-(phenylmethyl)-N-(4-piperidinylmethyl)-urea | 1629138-41-5 | 99.6% | 329.48 g/mol | C20H31N3O | 200 MG
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SRI-011381 is an orally active transforming growth factor-β (TGF-β)/Smad signaling agonist reported to exhibit neuroprotective effects. Intended for research use only, the compound is provided with a defined chemical formula, CAS identifier, and analytical data to support laboratory studies.
- Orally active TGF-β signaling agonist suitable for in vitro and in vivo studies.
- Reported neuroprotective effects in preclinical models.
- High purity analytical grade for consistent experimental results.
- Available as solid and as solution in DMSO for flexible use.
- Characterized by a defined molecular weight for dosing calculations.
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