Quinolines and derivatives
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Filtered Search Results
eMolecules 4965-36-0 | 7-Bromoquinoline | Apollo Scientific | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 25g | 562439580
7-Bromoquinoline | Apollo Scientific | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 95.000 | Brc1ccc2cccnc2c1 | 25g | 562439580
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5000745599 M-PEG10-AMINE 250MG
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Medchemexpress LLC LM11A-31 100mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 100 MG
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LM11A-31 a non-peptide p75NTR (neurotrophin receptor p75) modulator is an orally active and potent proNGF (nerve growth factor) antagonist LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer s disease mouse models with mid- to late-stage disease progression[1][2]
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Medchemexpress LLC Amino-PEG3-C2-amine | 929-75-9 | MFCD00628164 | 99.1% | 192.26 g/mol | C8H20N2O3 | 1 G
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Amino-PEG3-C2-amine is a short polyethylene glycol (PEG) spacer bearing a terminal primary amine, intended for use as a PROTAC linker and general bioconjugation. It provides three ethylene glycol units to improve solubility and flexibility, while the amino group enables straightforward coupling chemistry for building complex conjugates.
- Short PEG spacer (three ethylene glycol units) for flexibility and solubility.
- Terminal primary amine suitable for coupling to carboxylic acids and activated esters.
- Liquid form simplifies handling and accurate dosing.
- High purity supports reliable synthetic outcomes.
- Useful in PROTAC linker synthesis and general bioconjugation applications.
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Apexbio Technology LLC Perillartine 30950-27-7 200mg
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Perillartine (CAS 30950-27-7) is a small molecule that modulates sweet taste perception by selectively interacting with the taste receptor type 1 member 2 (Tas1r2) subunit Studies indicate that Perillartine functions as a sweetener by activating Tas1r2 in a species-dependent manner thereby influencing taste signaling pathways This compound is primarily utilized in the development of food additives and in investigations of taste receptor function and chemosensory signaling mechanisms
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TARGETMOL CHEMICALS INC GEVOTROLINE 5MG
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502693857 GEVOTROLINE 5MG
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![eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Ambeed | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 100g | 491642014](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471436.jpg-250.jpg)
eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Ambeed | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 100g | 491642014
4-Chloro-3-nitroquinoline | Ambeed | 39061-97-7 | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 100g | 491642014
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TARGETMOL CHEMICALS INC SEPANTRONIUM BROMIDE 25MG
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502694034 SEPANTRONIUM BROMIDE 25MG
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5000745361 CHDI-00484077 200MG
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![Medchemexpress LLC Ethanesulfonic acid, 2-[(aminoiminomethyl)amino]- | 543-18-0 | 99.9% | 167.19 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436072-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanesulfonic acid, 2-[(aminoiminomethyl)amino]- | 543-18-0 | 99.9% | 167.19 | 100 MG
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Guanidinoethyl sulfonate (Standard) is an analytical standard and an orally available, blood-brain permeable competitive inhibitor of taurine transporters. It acts as a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM) and shows weak agonist/antagonist effects on GABAA receptors. It inhibits taurine transmembrane transport, blocks glycine-mediated chloride influx, and may regulate brain pH for neuroprotective effects, useful in studies of ischemic brain injury. It is applied in qualitative, quantitative, and methodological research experiments including HPLC, GC, and MS.
- Analytical standard for research
- Orally available and blood-brain permeable
- Inhibits taurine transporters
- Antagonizes glycine receptors
- Modulates GABAA receptors
- Blocks glycine-mediated chloride influx
- May offer neuroprotective effects
- Used in HPLC, GC, and MS applications
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eMolecules 5622-36-6 | Methyl 2-(quinolin-6-yl)acetate | ChemScene | MFCD04038669 | 201.225 | C12H11NO2 | 98.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 569143723
Methyl 2-(quinolin-6-yl)acetate | ChemScene | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 98.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 569143723
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Medchemexpress LLC Ipatasertib | 1001264-89-6 | 458.00 | 200 MG
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Ipatasertib (GDC-0068) is an orally active, highly selective, and ATP-competitive pan-Akt inhibitor. It activates FoxO3a and NF-κB through Akt inhibition, leading to p53-independent activation of PUMA, and induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models.
- Orally active and highly selective pan-Akt inhibitor
- ATP-competitive inhibition of Akt1, Akt2, and Akt3
- Synchronously activates FoxO3a and NF-κB
- Leads to p53-independent activation of PUMA
- Induces apoptosis in cancer cells
- Inhibits tumor growth in xenograft mouse models
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Medchemexpress LLC MYF-03-176 | 2857937-59-6 | 99.72% | 410.37 | 25 MG
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MYF-03-176 is an orally active inhibitor of TEAD, suppressing TEAD transcriptional activity with an IC50 of 11 nM. It inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells and demonstrates strong antitumor efficacy in an MPM mouse xenograft model. The IC50 values for TEAD1, TEAD3, and TEAD4 are 47, 32, and 71 nM, respectively.
- Orally active inhibitor of TEAD
- Suppresses TEAD transcriptional activity with an IC50 of 11 nM
- Inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells
- Demonstrates strong antitumor efficacy in MPM mouse xenograft model
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5000656975 DIRECT YELLOW 86 50MG
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Apexbio Technology LLC SKA 31 40172-65-4 100mg
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SKA 31 (CAS 40172-65-4) is a small-molecule activator of calcium-activated potassium channels selectively targeting KCa3 1 KCa2 2 KCa2 1 and KCa2 3 subtypes It exhibits EC50 values of 260 nM for KCa3 1 1 9 M for KCa2 2 and 2 9 M for both KCa2 1 and KCa2 3 By facilitating the activation of these channels SKA 31 enhances endothelium-derived hyperpolarizing factor (EDHF) responses This compound is employed to investigate endothelial function and signal transduction with notable utility in studies exploring blood pressure regulation and related vascular mechanisms
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