Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,351 – 1,365 of 4,235 results

1,351

eMolecules 1016780-82-7 | 3-Quinolinecarboxylic acid, 6-bromo-4-chloro-8-methyl-, ethyl ester | MFCD09933645 | 1g

Medchem Express | GAT211 | 5mg | 736631350 | HY-113689 | 102704-40-5 | MFCD02165420 | 342.398 | C22H18N2O2

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1,352

TARGETMOL CHEMICALS INC O-DESMETHYL QUINIDINE 100MG

Also available in 500 mg and bulk. Please contact Fisher for quotes. O-Desmethyl Quinidine is a novel quinidine analog with significant antiarrhythmic activity and low acute toxicity that may be useful in the treatment of cardiac arrhythmias. purity: 100%

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1,353

Apexbio Technology LLC LDE225 (NVP-LDE225,Erismodegib) 956697-53-3 200mg

LDE225 (NVP-LDE225 Erismodegib CAS 956697-53-3) is a small molecule antagonist of the Smoothened (Smo) receptor a central component in the Hedgehog (Hh) signaling pathway implicated in oncogenic processes Identified through cell-based high-throughput screening of combinatorial libraries LDE225 demonstrates potent inhibition of Smo with IC50 values of 1 3 nM in murine models and 2 5 nM in human systems Preclinical studies showed marked suppression of tumor growth in medulloblastoma xenograft mouse models following oral administration with evidence of blood-brain barrier permeability LDE225 is widely used for investigating Hh pathway modulation and its role in cancer research

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1,354

Apexbio Technology LLC RU.521 2262452-06-0 10mg

RU 521 (CAS 2262452-06-0) is a selective inhibitor of cyclic GMP-AMP synthase (cGAS) an enzyme responsible for synthesizing cGAMP upon recognition of cytosolic double-stranded DNA By interfering with cGAS-mediated cGAMP production RU 521 suppresses activation of the type I interferon signaling pathway Experimental studies demonstrate that RU 521 reduces cGAS-dependent signal transduction and interferon responses in reporter assays containing double-stranded DNA In macrophages derived from Aicardi-Gouti res syndrome mouse models RU 521 lowers basal interferon expression This compound is a valuable tool for investigating cGAS-dependent innate immune pathways

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1,355

Sigma Aldrich Fine Chemicals Biosciences Ciprofloxacin hydrochloride for peak identification European Pharmacopoeia (EP) Reference Standard | 86393-32-0 | MFCD00242856 |

Ciprofloxacin hydrochloride for peak identification European Pharmacopoeia (EP) Reference Standard | Mol Wt: 385.82 | 86393-32-0 | MFCD00242856 |

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1,356

Chem-Impex International, Inc. 7-(4-Bromo-butoxy)-3,4-dihydro-1H-quinolin-2-one | 129722-34-5 | MFCD06658540 | 5G

7-(4-Bromo-butoxy)-3,4-dihydro-1H-quinolin-2-one, 129722-34-5, MFCD06658540, 5G

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1,357

Medchemexpress LLC Sulfo-Cy3 azide | 1801695-56-6 | MFCD30527437 | 99.6% | 806.97 | C35H46N6O10S3 | 10 MG

Sulfo-Cy3 Azide is a water-soluble Cy3 fluorescent dye bearing an azide functional group for bioorthogonal click chemistry. It is designed for labeling sensitive biomolecules, such as proteins, via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC). The dye exhibits excitation/emission around 550/570 nm and is supplied in research pack sizes.

Water-soluble cyanine dye suitable for aqueous labeling reactions.
Azide functional group enables CuAAC and SPAAC click chemistry.
Excitation/emission approximately 550/570 nm for bright fluorescence.
Soluble in DMSO at 50 mg/mL (requires sonication; use fresh DMSO).
High purity suitable for research applications.

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1,358

Medchemexpress LLC Ag490 (Tyrphostin AG490) | 133550-30-8 | 99.9% | 200 MG

AG490 (Tyrphostin AG490) is a small-molecule tyrosine kinase inhibitor that targets JAK2, JAK3, and EGFR, blocking downstream STAT activation. It is supplied for research use and is available as a solid and as DMSO solution for in vitro biochemical and cell-based assays.

Inhibits JAK2/3 and EGFR-mediated STAT signaling.
Suitable for in vitro kinase inhibition and cell signaling studies.
High analytical purity reported at 99.86%.
Available as a solid and as a DMSO solution for assay preparation.
CAS number 133550-30-8 supports unambiguous identification.

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1,359

Medchemexpress LLC DAPT | 208255-80-5 | 100.0% | 200 MG

DAPT is a potent and orally active γ-secretase inhibitor. It inhibits the activation of Notch 1 signaling and induces cell differentiation, autophagy, and apoptosis. This compound exhibits neuroprotection activity and holds potential for the treatment of autoimmune and lymphoproliferative diseases, degenerative diseases, and various cancers.

Inhibits γ-secretase with IC50s of 115 nM for total amyloid-β (Aβ) and 200 nM for Aβ42.
Inhibits activation of Notch 1 signaling.
Induces cell differentiation, autophagy, and apoptosis.
Exhibits neuroprotection activity, particularly in cerebral ischemia models.
Potential therapeutic agent for autoimmune and lymphoproliferative diseases.
Potential therapeutic agent for degenerative diseases and cancers.
Useful in research for Alzheimer's disease, cell differentiation, autophagy, and apoptosis.

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1,360

eMolecules AZIDO-PEG2-C2-AMINE 100MG

5000191098 AZIDO-PEG2-C2-AMINE 100MG

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1,361

eMolecules 72716-87-1 | 2-methoxypyridine-4-carbaldehyde | Pharmablock | MFCD06410680 | 137.138 | C7H7NO2 | 97.000 | COc1cc(C=O)ccn1 | 25mg | 551201750

2-methoxypyridine-4-carbaldehyde | Pharmablock | 72716-87-1 | MFCD06410680 | 137.138 | C7H7NO2 | 97.000 | COc1cc(C=O)ccn1 | 25mg | 551201750

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1,362

Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 50 MG

Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine also acts as a K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM. It can be utilized for malaria, systemic lupus erythematosus, and cancer research.

Analytical standard of Mefloquine.
Intended for research and analytical applications.
Orally active and potent quinoline antimalarial agent.
Anti-SARS-CoV-2 entry inhibitor.
K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM.
Applicable for malaria, systemic lupus erythematosus, and cancer research.
Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.

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1,363

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000693438 ETHIDIUM HOMODIMER 500UG

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1,364

Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | MFCD00069218 | 100.0% | 750.70 g/mol | C33H44BrN5O8S | 5 MG

Bromocriptine mesylate is the methanesulfonate salt of bromocriptine, a semisynthetic ergot-derived dopamine D2/D3 receptor agonist used in research. It shows high affinity for D2 receptors (pKi ≈ 8.05) and is provided as both a solid and solution format for laboratory and analytical applications.

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1,365

Selleck Chemical LLC Bemnifosbuvir Hemisulfate-25MG

Bemnifosbuvir Hemisulfate (AT-527 RG-6422 RO 7496998) is a hemi-sulfate salt of AT-511 AT-511 is a potent inhibitor of SARS-CoV-2 with an EC90 of 0 47 M

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Quinolines and derivatives

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TARGETMOL CHEMICALS INC O-DESMETHYL QUINIDINE 100MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC LDE225 (NVP-LDE225,Erismodegib) 956697-53-3 200mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC RU.521 2262452-06-0 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfo-Cy3 azide | 1801695-56-6 | MFCD30527437 | 99.6% | 806.97 | C35H46N6O10S3 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ag490 (Tyrphostin AG490) | 133550-30-8 | 99.9% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DAPT | 208255-80-5 | 100.0% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | MFCD00069218 | 100.0% | 750.70 g/mol | C33H44BrN5O8S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC Bemnifosbuvir Hemisulfate-25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More