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Filtered Search Results
Chemscene CHEMSCENE
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5000580069 RESIQUIMOD 250MG
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Medchemexpress LLC DBCO-amine (GMP) | 1255942-06-3 | 276.33 | 100 MG
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DBCO-amine (GMP) is a GMP grade DBCO-amine. It is a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. It is used in the synthesis of antibody-drug conjugates (ADCs).
- Contains a DBCO group
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
- Used in the synthesis of antibody-drug conjugates (ADCs)
- For research use only
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TARGETMOL CHEMICALS INC Levosimendan 200MG
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Also available in 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without a rise in intracellular calcium. Levosimendan exerts its effect by increasing calcium sensitivity of myocytes by binding to cardiac troponin C in a calcium-dependent manner. Purity 99.7%
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Apexbio Technology LLC β-Naphthoflavone 6051-87-2 200mg
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-Naphthoflavone (CAS 6051-87-2) also known as 5 6-benzoflavone is a small molecule that acts as a potent agonist of the aryl hydrocarbon receptor (AhR) Activation of AhR by -naphthoflavone upregulates the expression of metabolizing enzymes including multiple cytochrome P450 isoforms (CYPs) and uridine 5 -diphospho-glucuronosyltransferases (UGTs) This compound is widely utilized in biomedical research to investigate xenobiotic metabolism enzyme induction and the regulation of detoxification pathways Additionally it has been studied for its potential role in chemoprevention due to its modulatory effects on metabolic enzymes
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428994 Q AGAROSE 6FF 25ML
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Apexbio Technology LLC 17-Hydroxyprogesterone 68-96-2 200mg
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17-Hydroxyprogesterone (68-96-2) is a small-molecule agonist targeting the progesterone receptor (PR) with partial agonist activity at glucocorticoid receptors (GR) and antagonist effects at mineralocorticoid receptors (MR) It modulates steroid hormone signaling pathways thereby influencing vascular tone and inflammation 17-Hydroxyprogesterone exerts its biological activity primarily through activation and modulation of steroid hormone receptors In animal models administration of 17-Hydroxyprogesterone demonstrates the ability to modulate vascular inflammation and uterine vascular tone Based on these pharmacological properties 17-Hydroxyprogesterone holds research potential in the screening of congenital adrenal hyperplasia and related metabolic syndromes as well as associations with respiratory distress syndrome and premature birth outcomes
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eMolecules R-TETRAHYDROFURAN-3-AMINE 1G
5000162391 R-TETRAHYDROFURAN-3-AMINE 1G
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Medchemexpress LLC Sugammadex sodium | 343306-79-6 | 98.0% | C72H104Na8O48S8 | 200 MG
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Sugammadex sodium is a synthetic γ-cyclodextrin derivative that acts as a reversal agent for neuromuscular block. It also shows a nephroprotective effect in ischemia-reperfusion injury.
- Acts as a reversal agent for neuromuscular block.
- Exhibits nephroprotective effects in ischemia-reperfusion injury.
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 25 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM (selectivity index >60-fold over PTP1B). It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity. It can be used to further investigate PTPN2 in diseases such as leukemia and melanoma.
- Induces PTPN2 degradation
- Reduces PTPN2 protein levels
- Enhances phosphorylation of STAT1 in Jurkat cells
- Promotes T cell proliferation under CD3/CD28 stimulation
- Amplifies B16F10 cell growth inhibition in the presence of IFN-γ
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656180 SULFO-CYANINE5.5 ALK 10MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000657040 DIRECT YELLOW 86 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656975 DIRECT YELLOW 86 50MG
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![Apexbio Technology LLC parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096693.png-250.jpg)
Apexbio Technology LLC parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] 25mg
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Parathyroid hormone (7-34) is a polypeptide antagonist targeting parathyroid hormone receptors (PTH1R and PTH2R) It is derived from Homo sapiens and Macaca fascicularis and is designed to modulate PTH receptor activity thereby influencing calcium and phosphate homeostasis Parathyroid hormone (7-34) exerts its biological activity primarily through competitive interaction with PTH receptors affecting absorption processes in bone kidney and intestinal tissues Based on these pharmacological properties parathyroid hormone (7-34) holds research potential in studies of mineral metabolism bone remodeling and calcium-phosphate balance disorders
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TARGETMOL CHEMICALS INC Dactolisib 200MG
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Also available in 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110alpha, 5 nM for p110gamma, 7 nM for p110delta, 75 nM for p110beta, and 20.7 nM for mTOR. Purity 99.71%
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383681 AMINO-PEG13-AMINE 250MG
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