Quinolines and derivatives
8-Hydroxy-7-iodo-5-quinolinesulfonic Acid, For Spectrophotometric Det. of Fe(III), 98.5%, MilliporeSigma™ Supelco™
CAS: 547-91-1 Molecular Formula: C10H7INNaO7S Molecular Weight (g/mol): 435.12 MDL Number: MFCD00006793 InChI Key: FNXKBSAUKFCXIK-UHFFFAOYSA-M Synonym: Ferron; Iodoxyquinolinesulfonic acid IUPAC Name: sodium 8-hydroxy-7-iodoquinoline-5-sulfonic acid hydrogen carbonate SMILES: [Na+].OC([O-])=O.OC1=C2N=CC=CC2=C(C=C1I)S(O)(=O)=O
Cayman Chemical DeferoxamInmesylate 1g
A bacterial siderophore that chelates iron; used experimentally to inhibit iron-dependent prolyl hydroxylases (EC50 = 17.8 µM), thus preventing the degradation of isoforms of HIF during normoxia
Medchemexpress LLC Deferoxamine (mesylate) | 138-14-7 | 99.8% | 20 MG
Deferoxamine mesylate is an iron chelator that binds to Fe(III) and other metal cations. It is widely used to reduce iron accumulation and deposition in tissues. This compound upregulates HIF-1α levels with good antioxidant activity, shows anti-proliferative activity, and can induce apoptosis and autophagy in cancer cells. It is applicable in studies of diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research.
- Binds to Fe(III) and other metal cations
- Reduces iron accumulation and deposition in tissues
- Upregulates HIF-1α levels
- Exhibits good antioxidant activity
- Shows anti-proliferative activity
- Induces apoptosis and autophagy in cancer cells
- Applicable in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research
Medchemexpress LLC Deferoxamine (mesylate) (Standard) | 138-14-7 | 99.8% | 25 MG
Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator that binds to Fe(III) and many other metal cations. It is widely used to reduce iron accumulation and deposition in tissues. It upregulates HIF-1α levels with good antioxidant activity and also shows anti-proliferative activity, inducing apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases, as well as anti-cancer and anti-COVID-19 research.
- Binds to Fe(III) and many other metal cations.
- Reduces iron accumulation and deposition in tissues.
- Upregulates HIF-1α levels.
- Exhibits good antioxidant activity.
- Shows anti-proliferative activity.
- Induces apoptosis and autophagy in cancer cells.
- Used in studies of diabetes and neurodegenerative diseases.
- Used in anti-cancer and anti-COVID-19 research.
Medchemexpress LLC Deferoxamine mesylate (standard) | 138-14-7 | 99.47% | 50 MG
Deferoxamine mesylate (Standard) is an analytical standard intended for research and analytical applications. It functions as an iron chelator, binding to Fe(III) and other metal cations, thereby reducing iron accumulation and deposition in tissues. This compound also upregulates HIF-1α levels and exhibits good antioxidant activity, along with anti-proliferative activity that can induce apoptosis and autophagy in cancer cells.
- Used in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research
- Serves as a reference standard for assays
- Frequently utilized in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC Deferoxamine mesylate (Standard) | 138-14-7 | 99.47% | 100 MG
Deferoxamine mesylate (Standard) is the analytical standard for Deferoxamine mesylate, intended for research and analytical applications. It is an iron chelator, binding to Fe(III) and other metal cations, and is widely used to reduce iron accumulation and deposition in tissues. It also upregulates HIF-1α levels with good antioxidant activity, shows anti-proliferative activity, and can induce apoptosis and autophagy in cancer cells. This compound can be used in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research.
- The compound is an analytical standard, serving as a reference standard for assays.
- Commonly employed in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
Cayman Chemical 4-HydroxyquInolIn 1g
A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
Cayman Chemical 4-HydroxyquInolIn 5g
A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
Cayman Chemical 4-HydroxyquInolIn 25g
A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
Cayman Chemical 4-HydroxyquInolIn 10g
A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
Medchemexpress LLC Deferoxamine mesylate | 138-14-7 | MFCD00058605 | 99.5% | 656.79 | C26H52N6O11S | 10 MG
Deferoxamine mesylate is an iron-chelating research standard used as a hypoxia mimetic and to chelate ferric ions in biochemical and cell biology studies. Provided as a solid for laboratory use; intended for research purposes only.
- Iron chelator and hypoxia mimetic for biochemical and cell biology studies.
- CAS number 138-14-7.
- Molecular weight 656.79 g/mol.
- Purity approximately 99.5% (per certificate of analysis).
- Supplied as a solid powder suitable for preparing stock solutions.
- Intended for research use only; not for human or veterinary use.
Apexbio Technology LLC Dp44mT 152095-12-0 200mg
Dp44mT (CAS 152095-12-0) is a small molecule iron chelator that selectively inhibits topoisomerase II a critical enzyme involved in chromosome segregation DNA replication and transcription In human breast cancer MDA-MB-231 cells Dp44mT exhibits a GI50 of approximately 100 nmol/L Experiments indicate that its cytotoxic effects are reduced in cells with diminished topoisomerase II expression underscoring target specificity Dp44mT treatment leads to the formation of covalent DNA-topoisomerase II complexes without affecting topoisomerase I or II These properties support its utility in studies on DNA damage enzymatic selectivity and mechanisms underlying cancer cell cytotoxicity