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Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.
A bacterial siderophore that chelates iron; used experimentally to inhibit iron-dependent prolyl hydroxylases (EC50 = 17.8 µM), thus preventing the degradation of isoforms of HIF during normoxia
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A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
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A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
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A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
A quinoline alkaloid; is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules; has been used as a precursor in the synthesis of compounds with antibacterial activity; has been used as a fluorescent detection reagent for iron(III) in bovine liver samples
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Deferoxamine mesylate is an iron-chelating research standard used as a hypoxia mimetic and to chelate ferric ions in biochemical and cell biology studies. Provided as a solid for laboratory use; intended for research purposes only.
Iron chelator and hypoxia mimetic for biochemical and cell biology studies.
CAS number 138-14-7.
Molecular weight 656.79 g/mol.
Purity approximately 99.5% (per certificate of analysis).
Supplied as a solid powder suitable for preparing stock solutions.
Intended for research use only; not for human or veterinary use.
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Dp44mT (CAS 152095-12-0) is a small molecule iron chelator that selectively inhibits topoisomerase II a critical enzyme involved in chromosome segregation DNA replication and transcription In human breast cancer MDA-MB-231 cells Dp44mT exhibits a GI50 of approximately 100 nmol/L Experiments indicate that its cytotoxic effects are reduced in cells with diminished topoisomerase II expression underscoring target specificity Dp44mT treatment leads to the formation of covalent DNA-topoisomerase II complexes without affecting topoisomerase I or II These properties support its utility in studies on DNA damage enzymatic selectivity and mechanisms underlying cancer cell cytotoxicity
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