Tetrahydroisoquinolines
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Filtered Search Results
Selleck Chemical LLC Solifenacin (YM905) S5238-25mg
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Solifenacin (YM905) is a competitive muscarinic receptor antagonist The binding of acetylcholine to these receptors particularly the M3 receptor subtype plays a critical role in the contraction of smooth muscle
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Chembridge Corporation ALKYL AMINE 4101917-05, 5GR
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6-methoxy-1,2,3,4-tetrahydroisoquinoline; CAS: 42923-77-3
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eMolecules 1199782-93-8 | ChemScene | 7-Bromo-1234-tetrahydronaphthalen-1-amine hydrochloride | 100mg | 569145785 | CS-0101640 | MFCD08544186 | 262.58 | C10H13BrClN
Ambeed | 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone | 250mg | 624119886 | A100260 | 126581-65-5 | MFCD03094564 | 233.036 | C8H6BrFO2
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eMolecules 41734-98-9 | 6-FLUORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE | AstaTech | MFCD00459397 | 203.216 | C12H10FNO | 95.000 | Fc1ccc2[nH]c3c(CCCC3=O)c2c1 | 0.25g | 721759634
6-FLUORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE | AstaTech | 41734-98-9 | MFCD00459397 | 203.216 | C12H10FNO | 95.000 | Fc1ccc2[nH]c3c(CCCC3=O)c2c1 | 0.25g | 721759634
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Medchemexpress LLC Olodanrigan | 1316755-16-4 | 98.9% | 100 MG
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Olodanrigan (EMA401) is a highly selective, orally active, and peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. This compound is currently under development as a therapeutic agent for neuropathic pain. Its analgesic action is attributed to the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, which effectively inhibits both DRG neuron hyperexcitability and the sprouting of DRG neurons.
- Highly selective AT2 receptor antagonist
- Orally active and peripherally restricted
- A therapeutic agent candidate for neuropathic pain
- Inhibits p38 and p42/p44 MAPK activation
- Prevents DRG neuron hyperexcitability and sprouting
- Purity of 98.9%
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 2 years or -20°C for 1 year
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Ambeed (S,S)-(-)-HYDROBENZOIN-1G
(S,S)-(-)-Hydrobenzoin, 1G, CAS# 2325-10-2, MFCD00064255, MOLWT: 214.26
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Medchemexpress LLC HY-10805A 5mg Medchemexpress, Almorexant (hydrochloride) CAS:913358-93-7 Purity:>98%
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Medchemexpress, HY-10805A 5mg Almorexant (HCl) CAS:913358-93-7 Almorexant hydrochloride (ACT 078573 hydrochloride) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Cephaeline dihydrochloride | 5853-29-2 | MFCD01732155 | 99.0% | 539.53 | C28H40Cl2N2O4 | 10 MG
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Cephaeline dihydrochloride is the dihydrochloride salt of cephaeline, a small-molecule research reagent that acts as a selective inhibitor of cytochrome P450 2D6. It is supplied as a solid, white to off-white powder with high purity and solubility properties suitable for in vitro and selected in vivo formulations.
- Selective CYP2D6 inhibitor with reported IC50 of 121 μM.
- High purity suitable for research use (≈99%).
- Molecular formula C28H40Cl2N2O4; molecular weight 539.53.
- Solid, white to off-white appearance.
- Soluble in DMSO and water; demonstrated in defined in vivo formulations.
- Recommended storage sealed, away from moisture and light; long-term storage in solvent at -80°C.
- Common applications include enzyme inhibition assays and pharmacology studies.
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eMolecules 63095-11-4 | Ambeed | 224-Trimethyl-1234-tetrahydroquinolin-7-ol | 1g | 665578581 | A1488963 | MFCD24549530 | 191.274 | C12H17NO
Ambeed | 224-Trimethyl-1234-tetrahydroquinolin-7-ol | 1g | 665578581 | A1488963 | 63095-11-4 | MFCD24549530 | 191.274 | C12H17NO
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eMolecules 625375-83-9 | Medchem Express | Tariquidar (methanesulfonate hydrate) | 10mg | 446258845 | HY-10550A | MFCD25372040 | 892.99 | C40H52N4O15S2
Medchem Express | Tariquidar (methanesulfonate hydrate) | 10mg | 446258845 | HY-10550A | 625375-83-9 | MFCD25372040 | 892.990 | C40H52N4O15S2
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eMolecules 29477-83-6 | Medchem Express | Narciclasine | 1mg | 446267508 | HY-16563 | MFCD01729949 | 307.258 | C14H13NO7
Medchem Express | 1-(Anilinocarbonyl)proline | 5mg | 559839690 | HY-134145 | 73096-22-7 | MFCD10011836 | 234.255 | C12H14N2O3
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Medchemexpress LLC HY-19121A 5mg Medchemexpress, TCV-309 (chloride) CAS:121494-09-5 Purity:>98%
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Medchemexpress, HY-19121A 5mg TCV-309 (chloride) CAS:121494-09-5 TCV-309 chloride is a potent and specific platelet activating factor (PAF) antagonist. TCV-309 chloride specifically inhibits PAF-induced aggregation of rabbit and human platelets, and [3H]PAF binding to rabbit platelet microsomes with IC50 values of 33 nM, 58 nM and 27 nM, respectively. TCV-309 chloride has beneficial effects in anaphylactic shock. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10550A 10mg Medchemexpress, Tariquidar (methanesulfonate, hydrate) CAS:625375-83-9 Purity:>98%
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Medchemexpress, HY-10550A 10mg Tariquidar (methanesulfonate, hydrate) CAS:625375-83-9 Tariquidar methanesulfonate, hydrate (XR9576 methanesulfonate, hydrate) is a potent and specific inhibitor of P-glycoprotein (P-gp) with a Kd of 5.1 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 832113-97-0 | 1-(2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophen-2-methylpropan-1-one | Oakwood Chemical | MFCD05864297 | 223.330 | C12H17NOS | 90.000 | CC(C)C(=O)c1c(N)sc2CCCCc12 | 1g | 537679627
1-(2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophen-2-methylpropan-1-one | Oakwood Chemical | 832113-97-0 | MFCD05864297 | 223.330 | C12H17NOS | 90.000 | CC(C)C(=O)c1c(N)sc2CCCCc12 | 1g | 537679627
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Medchemexpress LLC 1(2H)-isoquinolinone, 5-hydroxy | 5154-02-9 | MFCD00006900 | 99.1% | 161.16 g/mol | C9H7NO2 | 10 MG
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1,5-Isoquinolinediol is a small-molecule PARP inhibitor used in research to modulate DNA repair and oxidative-stress pathways. It exhibits potent PARP inhibition and has been reported to reduce diabetes-induced NADPH oxidase-derived oxidative stress in retinal models. The compound is provided as a solid with high purity and is typically prepared in DMSO for in vitro and in vivo studies.
- Potent PARP inhibition (IC50 0.18-0.37 μM).
- Attenuates NADPH oxidase-derived oxidative stress in retinal models.
- High purity suitable for biochemical and cell-based assays.
- Soluble in DMSO (≈37 mg/mL) for convenient stock preparation.
- Stable as a powder when stored cold for extended periods.
- Applicable for studies of DNA repair, oxidative stress, and cell death pathways.
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