Tetrapyrroles and derivatives
Cayman Chemical N-methyl ProtoporphyrIn IX 5mg
A transition state analog that potently inhibits protoporphyrin IX ferrochelatase (Ki = 10 nM), blocking the terminal step of the heme biosynthetic pathway
Enzo Life Sciences Zinc(II) Protoporphyrin IX (25mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.
Abcam SB-3CT, MMP-2 and MMP-9 inhibitor, 5MG
MW 306.4 Da, Purity >98%. Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor (Ki values are 13.9 and 600 nM for MMP-2 and MMP-9 respectively). Does not alter the activity of MMP-1, MMP-3 or MMP-7 (Ki values are 206 (MMP-1), 15 (MMP-3) and 96 (MMP-7) μM). Neuroprotective and blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PDTC (Ammonium pyrrolidinedithiocarbamate), NF-kappaB inhibitor antio x idant, 100MG
MW 164.3 Da. Selective NF-κB inhibitor. Inhibits translation of nitric oxide synthase mRNA to prevent induction. Metal ion chelator and antioxidant. Active in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Z-Prolyl-prolinal (Z-Pro-Pro-CHO), Prolyl endopeptidase inhibitor, 5MG
MW 330.4 Da, Purity >97%. Z-Prolyl-prolinal (Z-Pro-Pro-CHO), Prolyl endopeptidase inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist, 25MG
MW 283.41 Da, Purity >99%. Selective protease-activated receptor 2 (PAR2) antagonist (IC₅₀ = 1.2 mM). Anti-inflamatory agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BIM 23056, Somatostatin receptor 5 (sst5) antagonist, 1MG
MW 1232.5 Da. BIM 23056, Somatostatin receptor 5 (sst5) antagonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam A 943931 dihydrochloride, H4 receptor antagonist, 50MG
MW 368.3 Da, Purity >99%. Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Thiouridine, RNA synthesis inhibitor, 100MG
MW 260.27 Da, Purity >99%. Ribonucleoside (Uridine ab143255) analog. Antisense agent. RNA synthesis inhibitor. Modifies oligos slated for RNA. Induces p53 and inhibits proliferation. Metabolically labels RNA for stability studies.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clozapine N-o x ide, Metabolite of Clozapine, 100MG
MW 342.8 Da, Purity >99%. Metabolite of atypical antipsychotic Clozapine (ab120019). Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Thiouridine, RNA synthesis inhibitor, 5MG
MW 260.27 Da, Purity >99%. Ribonucleoside (Uridine ab143255) analog. Antisense agent. RNA synthesis inhibitor. Modifies oligos slated for RNA. Induces p53 and inhibits proliferation. Metabolically labels RNA for stability studies.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Zinc(II)-protoporphyrin IX | 15442-64-5 | 98.9% | 626.02 | C34H32N4O4Zn | 5 MG
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is a porphyrin-based small molecule used in biomedical research as a competitive heme oxygenase-1 (HO-1) inhibitor and as a biochemical marker of iron deficiency. It is supplied as a solid for laboratory studies and should be stored sealed and protected from moisture at low temperatures for stability.
- Competitive heme oxygenase-1 (HO-1) inhibitor
- Used as a screening marker of iron deficiency in biological samples
- High purity suitable for research assays (98.9%)
- Available in milligram-scale packages for laboratory use
- Requires sealed, moisture-free storage at low temperature
Medchemexpress LLC HY-101193 10mg Medchemexpress, Zinc Protoporphyrin CAS:15442-64-5 Purity:>98%
Medchemexpress, HY-101193 10mg Zinc Protoporphyrin CAS:15442-64-5 Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is a competitive heme oxygenase-1 (HO-1) inhibitor, markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2. Zinc Protoporphyrin is a normal metabolite formed in trace amounts during heme biosynthesis and used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
