Tetrapyrroles and derivatives
Abcam (R,S)-CPP, NMDA antagonist, 10MG
MW 252.2 Da. Potent, competitive NMDA antagonist. See separate isomer (ab120159). Also available in simple stock solutions (ab146720) - add 1 ml of water to get an exact, ready-to-use concentration.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Tin protoporphyrin IX dichloride(Synonyms: Tin Protoporphyrin Dichloride, SnPP, SnPP IX, Tin(IV) Protoporphyrin Dichloride), 50mg, CAS: 14325-05-4.
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Abcam Rhodadyn™ B10, Negative control for Rhodadyn™ C10, 5MG
MW 322.44 g/mol, Purity >98%. Negative control for Rhodadyn™ C10 (ab120795). Demonstrates no significant inhibition of dynamin I or dynamin II in vitro GTPase activity at concentrations up to 300 μM and has no effect on clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture. Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012).
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical ZInc ProtoporphyrIn-9 25mg
A competitive inhibitor of heme oxygenase that also inhibits soluble guanylyl cyclase and inactivates the NOS isoforms nNOS, iNOS, and eNOS (IC50s = 0.8, 4, and 5 μM, respectively); used to assess iron status and to diagnose iron disorders and has shown therapeutic potential in hyperbilirubinemia
Chemscene ChemScene | 1H-Indene-1,2(3H)-dione | 5G | CS-W014296 | 0.97 | 16214-27-0| MFCD00463378 | 146.15
ChemScene | 1H-Indene-1,2(3H)-dione | 5G | CS-W014296 | 0.97 | 16214-27-0| MFCD00463378 | 146.15
Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from equine heart, 9007-43-6, MFCD00130890, 50 mg
≥95% (SDS-PAGE), Synonym: Cytochrome c from horse heart. The specific sites and extent of oxidation in horse cytochrome c treated with H2O2 and UV were characterized. It was suggested that the state of these sites could be used as a biomarker for the oxidative environment in a cell.
Cayman Chemical N-methyl ProtoporphyrIn IX 5mg
A transition state analog that potently inhibits protoporphyrin IX ferrochelatase (Ki = 10 nM), blocking the terminal step of the heme biosynthetic pathway
Research Products International Corp Cyanocobalamin (Vitamin B12), 100 Milligrams
Common vitamin of the Vitamin B12 family.
Abcam SB 242084 hydrochloride, 5-HT2C antagonist, 50MG
MW 431.3 Da, Purity >98%. Potent, selective 5-HT2C antagonist (pKi values are 9 (5-HT2C), 7 (5-HT2B), 6.8 (5-HT2A), 6.4 (5-HT1A), 6.4 (5-HT1B), 6.4 (5-HT1D), 6 (5-HT1E), <6.1 (5-HT1F), <5.5 (5-HT4), 6 (5-HT6), 6.1 (5-HT7), 6.2 (D2), 6.2 (D3) and <5 (α1)). Blood-brain barrier permeable. Anxiolytic activity *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Dihydrokainic acid, EAAT2 (GLT-1) inhibitor, 1MG
MW 215.25 Da. Selective, non-transportable inhibitor of glutamate transporter EAAT2 (GLT-1) (Ki = 23 μM). 130-fold selective over EAAT1 and EAAT3 (Ki > 3 mM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam 5-Aza-2'-deo x ycytidine (Decitabine), DNMT1 inhibitor, 10MG
MW 228.21 Da, Purity >99%. Potent DNA methyltransferase 1 (DNMT1) inhibitor (IC₅₀ = 0.2 μM). Incorporated into DNA, inhibits DNMT1 activity to induce DNA hypomethylation. Interferes with protein synthesis. Shows antimetabolic and anticancer activities in vitro. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam x estospongin C, IP3 receptor antagonist, 10UG
MW 446.72 g/mol, Purity >90%. Potent, selective, reversible IP₃ receptor antagonist (IC₅₀ = 350 nM). Inhibits IP₃-mediated Ca²+ release from ER and SR. 30-Fold selectivity over ryanodine receptor. Inhibits voltage-dependent Ca²+ and K+ channels at higher concentrations. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam UDP-glucose, Highly P2Y14 agonist, 100MG
MW 610.27 Da. Highly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).
The product is subject to the following: Abcam Restricted Use Statement